Murine tumor and normal tissue blood flow measured by laser doppler flowmetry: Effect of nicotinamide, flunarizine and hydralazine

1989 ◽  
Vol 17 ◽  
pp. 199 ◽  
Author(s):  
Eamonn P. Dunphy ◽  
Matthew A. Spear ◽  
Mary A. Frankhauser ◽  
J. Martin Brown
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Normal Tissue ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Murine Tumor

scholarly journals Evaluation of the marginal gingival health using laser doppler flowmetry

2006 ◽  
Vol 17 (3) ◽  
pp. 219-222 ◽  
Author(s):  
Hakan Develioglu ◽  
Bülent Kesim ◽  
Aykut Tuncel
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Plaque Index ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Gingival Health ◽  
Significant Difference ◽  
Clinical Indices ◽  
And Control

The purposes of this study were to compare the gingival blood flow (GBF) in test sites (teeth retaining fixed partial dentures) and control sites (contralateral natural teeth) and investigate whether there is any relationship between clinical indices and GBF values. Twelve healthy subjects (6 females and 6 males) aged 20 to 54 years were enrolled this study. The GBF was measured from the middle point of the marginal gingiva in the test and control sites using laser Doppler flowmetry (LDF). Additionally, plaque index, gingival index and probing depth measurements were recorded. Statistically significant difference (p<0.05) was found between the test and control sites for marginal GBF. In contrast, no significant difference (p>0.05) was found between test and control sites with respect to the clinical indices, except for plaque index. The findings of this study suggest that there is a significant relation between resin-bonded fixed partial dentures with margins located subgingivally and marginal GBF. Clinical indices are helpful to collect information about the clinical health status of gingival tissues, but GBF is a good tool to measure gingival tissue blood flow and assess periodontal health. In conclusion, laser Doppler flowmetry can be used together with clinical indices to evaluate the marginal gingival health.

The use of laser Doppler flowmetry to evaluate oral soft tissue blood flow in humans: A review

2018 ◽  
Vol 86 ◽  
pp. 58-71 ◽  
Author(s):  
Ayepa Alain Kouadio ◽  
Fabienne Jordana ◽  
N’goran Justin Koffi ◽  
Pierre Le Bars ◽  
Assem Soueidan
Keyword(s):  
Blood Flow ◽  
Soft Tissue ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry ◽  
Oral Soft Tissue

Relative Importance of Flow versus  Pressure in Splanchnic Perfusion during Cardiopulmonary Bypass in Rabbits

2000 ◽  
Vol 92 (2) ◽  
pp. 457-457 ◽  
Author(s):  
Olivier Bastien ◽  
Vincent Piriou ◽  
Abdellah Aouifi ◽  
Claire Flamens ◽  
Rhys Evans ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cardiopulmonary Bypass ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Analysis Of Covariance ◽  
Tissue Blood Flow ◽  
Splanchnic Perfusion ◽  
Doppler Flowmetry ◽  
Significant Difference ◽  
Splanchnic Ischemia

Background Decreased gastrointestinal perfusion has been reported during cardiopulmonary bypass (CPB). Conflicting results have been published concerning thresholds of pressure and flow to avoid splanchnic ischemia during CPB. This study compared splanchnic perfusion during independent and randomized variations of CPB pump flow or arterial pressure. Methods Ten rabbits were studied during mild hypothermic (36 degrees C) nonpulsatile CPB using neonatal oxygenators. Simultaneous measurements of tissue blood flow in four different splanchnic areas (gastric, jejunum, ileum, and liver) were performed by laser Doppler flowmetry (LDF) before CPB (T0) and during a 4-step factorial experimental block design. Pressure and flow were alternatively high or low in random order. Results Laser Doppler flowmetry was significantly lower than pre-CPB value but was better preserved (analysis of covariance) in all organs, except liver, when CPB flow was high, whatever the pressure. Splanchnic LDF values in the low- versus high-flow groups expressed as perfusion unit were (mean +/- SD): stomach, 94+/-66 versus 137+/-75; jejunum, 118+/-78 versus 172+/-75; ileum, 95+/-72 versus 146+/-83; and liver, 79+/-72 versus 108+/-118. No significant difference of LDF was observed between the high- and low-pressure groups, whatever the flow, except for liver: stomach, 115+/-64 versus 117+/-83; jejunum, 141+/-80 versus 148+/-83; ileum, 127+/-87 versus 114+/-76; liver, 114+/-88 versus 73+/-70. Conclusion Prevention of splanchnic ischemia during CPB should focus on preservation of high CPB blood flow rather than on high pressure.

scholarly journals Clinical significance of tissue blood flow during esophagectomy by laser Doppler flowmetry

2001 ◽  
Vol 122 (6) ◽  
pp. 1101-1106 ◽  
Author(s):  
Yoshifumi Ikeda ◽  
Masanori Niimi ◽  
Shigenao Kan ◽  
Tomoo Shatari ◽  
Hiroshi Takami ◽  
...  
Keyword(s):  
Blood Flow ◽  
Clinical Significance ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Doppler Flowmetry

Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow

1986 ◽  
Vol 61 (2) ◽  
pp. 666-672 ◽  
Author(s):  
G. J. Smits ◽  
R. J. Roman ◽  
J. H. Lombard
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Electromagnetic Flowmeter ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Organ Blood Flow ◽  
Doppler Flowmetry ◽  
Laser Doppler Flow ◽  
Doppler Flow

In this study the technique of laser-Doppler flowmetry was evaluated for the measurement of tissue blood flow by comparing laser-Doppler flow (LDF) signal in the renal cortex, gracilis muscle, and cremaster muscle of anesthetized rats to whole-organ blood flow measured with an electromagnetic flowmeter or radioactive microspheres. In vitro, LDF signal was closely correlated (r = 0.99) to changes in erythrocyte velocity generated with a rotating wheel. Although individual LDF readings varied in situ, mean LDF signal calculated from multiple readings on the tissue surface were significantly correlated (r = 0.74–0.95) with tissue blood flows measured at various perfusion pressures. However, significant differences in the slope of the LDF signal vs. blood flow relationship were observed in different tissues and with different methods of measurement in the same tissue. This study indicates that mean laser-Doppler flow signal provides a good estimate of tissue blood flow, provided a sufficient number of points is scanned. However, there appears to be no universal calibration factor for the method.

A fast time-domain algorithm for the assessment of tissue blood flow in laser-Doppler flowmetry

2010 ◽  
Vol 55 (13) ◽  
pp. N383-N394 ◽  
Author(s):  
Tiziano Binzoni ◽  
Chandra Sekhar Seelamantula ◽  
Dimitri Van De Ville
Keyword(s):  
Blood Flow ◽  
Laser Doppler Flowmetry ◽  
Time Domain ◽  
Laser Doppler ◽  
Tissue Blood Flow ◽  
Fast Time ◽  
Doppler Flowmetry

Laser-Doppler flowmetry reveals rapid perfusion changes in adipose tissue of lean and obese females

2006 ◽  
Vol 291 (5) ◽  
pp. E1025-E1030 ◽  
Author(s):  
P. Wellhöner ◽  
D. Rolle ◽  
P. Lönnroth ◽  
L. Strindberg ◽  
M. Elam ◽  
...  
Keyword(s):  
Blood Flow ◽  
Adipose Tissue ◽  
Laser Doppler Flowmetry ◽  
Laser Doppler ◽  
Whole Body ◽  
Tissue Blood Flow ◽  
Flow Measurements ◽  
Doppler Flowmetry ◽  
Reflex Responses ◽  
Obese Subjects

The present study aimed to evaluate adipose tissue blood flow (ATBF) by means of laser-Doppler flowmetry (LDF) in humans. Lower body negative pressure (LBNP) and straining known to affect epidermal blood flow through the autonomic nervous system were performed in 11 lean and 11 obese female volunteers. ATBF changes were compared between both groups and also discriminated from skin blood flow (SBF) responses of the immediate vicinity. Additionally, LDF measurements were compared with flow measurements using 133xenon washout in 10 lean subjects during whole body cooling. LDF estimations of SBF and ATBF showed a positive correlation to 133Xe during cooling. SBF and ATBF were reduced to the same extent in both lean and obese subjects during LBNP. Straining induced divergent changes in SBF and ATBF: initially SBF decreased while ATBF increased, but toward the end of straining SBF increased above baseline and ATBF returned down to baseline level. Those changes were similar in both weight groups. Interestingly, only in obese subjects, both LBNP and straining were followed by ATBF augmentation, while SBF levels remained stable. In conclusion, LDF compares with 133Xe washout in monitoring ATBF during tonic perfusion changes. Its strength, however, lies in the detection of rapid flow alterations within the subcutaneous tissue, allowing the evaluation of reflex responses of the subcutaneous microcirculation. Interestingly, those rapid changes in SBF and ATBF can be both concordant and discordant. With regard to ATBF, vasoconstrictor components of the reflex responses were similar in lean and obese subjects, whereas vasodilatory responses were more pronounced in obese volunteers.

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