Biological properties of “naked” metal nanoparticles☆

2008 ◽  
Vol 60 (11) ◽  
pp. 1289-1306 ◽  
Author(s):  
R BHATTACHARYA ◽  
P MUKHERJEE
2021 ◽  
pp. 0958305X2198988
Author(s):  
Nur Syakirah Rabiha Rosman ◽  
Noor Aniza Harun ◽  
Izwandy Idris ◽  
Wan Iryani Wan Ismail

The emergence of technology to produce nanoparticles (1 nm – 100 nm in size) has drawn significant researchers’ interests. Nanoparticles can boost the antimicrobial, catalytic, optical, and electrical conductivity properties, which cannot be achieved by their corresponding bulk. Among other noble metal nanoparticles, silver nanoparticles (AgNPs) have attained a special emphasis in the industry due to their superior physical, chemical, and biological properties, closely linked to their shapes, sizes, and morphologies. Proper knowledge of these NPs is essential to maximise the potential of biosynthesised AgNPs in various applications while mitigating risks to humans and the environment. This paper aims to critically review the global consumption of AgNPs and compare the AgNPs synthesis between conventional methods (physical and chemical) and current trend method (biological). Related work, advantages, and drawbacks are also highlighted. Pertinently, this review extensively discusses the current application of AgNPs in various fields. Lastly, the challenges and prospects of biosynthesised AgNPs, including application safety, oxidation, and stability, commercialisation, and sustainability of resources towards a green environment, were discussed.


Author(s):  
Malathi Balasubramaniyan ◽  
Abdul Azeez Nazeer ◽  
Vimalraj Vinayagam ◽  
Sudarshana Deepa Vijaykumar

Metals such as silver, gold, and copper were used in ancient times for their medicinal properties. When these metals are converted to nanoparticles, they show unique and advanced physicochemical and biological properties due to their enhanced surface to volume ratio. Hence, these properties are utilized by researchers to develop highly specific diagnostic tools as well as a therapeutic agent against cancer. Cancer is a complex disease-causing desolation and death. Early detection and treatment is the only way to evade mortality. This chapter focuses on metal nanoparticles used as a theranostic agent against cancer. It summarizes the synthesis methodology along with their advantages, drawbacks and characterizations. Their recent application in diagnosing and treating cancer has also been highlighted.


Author(s):  
David A. Agard ◽  
Yasushi Hiraoka ◽  
John W. Sedat

In an effort to understand the complex relationship between structure and biological function within the nucleus, we have embarked on a program to examine the three-dimensional structure and organization of Drosophila melanogaster embryonic chromosomes. Our overall goal is to determine how DNA and proteins are organized into complex and highly dynamic structures (chromosomes) and how these chromosomes are arranged in three dimensional space within the cell nucleus. Futher, we hope to be able to correlate structual data with such fundamental biological properties as stage in the mitotic cell cycle, developmental state and transcription at specific gene loci.Towards this end, we have been developing methodologies for the three-dimensional analysis of non-crystalline biological specimens using optical and electron microscopy. We feel that the combination of these two complementary techniques allows an unprecedented look at the structural organization of cellular components ranging in size from 100A to 100 microns.


2015 ◽  
Vol 57 ◽  
pp. 177-187 ◽  
Author(s):  
Jennifer N. Byrum ◽  
William Rodgers

Since the inception of the fluid mosaic model, cell membranes have come to be recognized as heterogeneous structures composed of discrete protein and lipid domains of various dimensions and biological functions. The structural and biological properties of membrane domains are represented by CDM (cholesterol-dependent membrane) domains, frequently referred to as membrane ‘rafts’. Biological functions attributed to CDMs include signal transduction. In T-cells, CDMs function in the regulation of the Src family kinase Lck (p56lck) by sequestering Lck from its activator CD45. Despite evidence of discrete CDM domains with specific functions, the mechanism by which they form and are maintained within a fluid and dynamic lipid bilayer is not completely understood. In the present chapter, we discuss recent advances showing that the actomyosin cytoskeleton has an integral role in the formation of CDM domains. Using Lck as a model, we also discuss recent findings regarding cytoskeleton-dependent CDM domain functions in protein regulation.


1975 ◽  
Vol 135 (1) ◽  
pp. 32-36 ◽  
Author(s):  
C. K. Osterland

Planta Medica ◽  
2011 ◽  
Vol 77 (12) ◽  
Author(s):  
N Miceli ◽  
MF Taviano ◽  
A Trovato ◽  
R De Pasquale ◽  
P Maimone ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
D Moreira ◽  
F Candido ◽  
M Siqueira ◽  
C Quaresma ◽  
E Guimarâes ◽  
...  

Planta Medica ◽  
2014 ◽  
Vol 80 (16) ◽  
Author(s):  
CA Aguiar ◽  
AM Ferreira ◽  
R Oliveira ◽  
F Baltazar ◽  
A Cunha

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
S Combrinck ◽  
J Linde ◽  
A Ludwiczuk ◽  
S Van Vuuren ◽  
J Van Rooy ◽  
...  

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