Reduced dietary intake of TLR2 and TLR4 stimulants favourably modifies lipid and inflammatory markers of cardiometabolic risk in healthy men

2016 ◽  
Vol 252 ◽  
pp. e171
Author(s):  
T. Faraj ◽  
C. Erridge
Keyword(s):  
Dietary Intake ◽  
Inflammatory Markers ◽  
Cardiometabolic Risk ◽  
Healthy Men

scholarly journals Dietary intake and cardiometabolic risk factors among Venezuelan adults: a nationally representative analysis

BMC Nutrition ◽  
2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Dina Goodman ◽  
Juan P. González-Rivas ◽  
Lindsay M. Jaacks ◽  
Maritza Duran ◽  
María Inés Marulanda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Dietary Intake ◽  
Cardiometabolic Risk ◽  
Dietary Diversity ◽  
Nutrition Transition ◽  
Cardiometabolic Risk Factors ◽  
Political Crisis ◽  
Food Groups

Abstract Background Increasing trends in global obesity have been attributed to a nutrition transition where healthy foods are replaced by ultra-processed foods. It remains unknown if this nutrition transition has occurred in Venezuela, a country undergoing a socio-political crisis with widespread food shortages. Methods We described dietary intake of Venezuelans from a nationally representative study conducted between 2014 and 2017. We conducted a cross-sectional analysis of dietary, sociodemographic, and clinical data from Venezuelans ≥20 years of age (n = 3420). Dietary intake was assessed using a semi-quantitative food frequency questionnaire. Standardized clinical and anthropometric measurements estimated obesity, type 2 diabetes, and hypertension. A Dietary Diversity Score (DDS) was calculated using an amended Minimum Dietary Diversity for Women score where the range was 0 to 8 food groups, with 8 being the most diverse. Analyses accounted for complex survey design by estimating weighted frequencies of dietary intake and DDS across sociodemographic and cardiometabolic risk-based subgroups. Results The prevalence of obesity was 24.6% (95% CI: 21.6–27.7), type 2 diabetes was 13.3% (11.2–15.7), and hypertension was 30.8% (27.7–34.0). Western foods were consumed infrequently. Most frequently consumed foods included coffee, arepas (a salted corn flour cake), and cheese. Mean DDS was 2.3 food groups (Range: 0–8, Standard Error: 0.07) and this score did not vary among subgroups. Men, younger individuals, and those with higher socioeconomic status were more likely to consume red meat and soft drinks once or more weekly. Women and those with higher socioeconomic status were more likely to consume vegetables and cheese once or more daily. Participants with obesity, type 2 diabetes, and hypertension had lower daily intake of red meat and arepas compared to participants without these risk factors. Conclusions Despite high prevalence of cardiometabolic risk factors, adults in Venezuela have not gone through a nutrition transition similar to that observed elsewhere in Latin America. Dietary diversity is low and widely consumed food groups that are considered unhealthy are part of the traditional diet. Future studies are needed in Venezuela using more comprehensive measurements of dietary intake to understand the effect of the socio-political crisis on dietary patterns and cardiometabolic risk factors.

Abstract: P455 DIETARY INTAKE OF DOCOSAPENTAENOIC ACID AND THE RISK OF ACUTE CORONARY SYNDROME IN HEALTHY MEN AND WOMAN

2009 ◽  
Vol 10 (2) ◽  
pp. e766
Author(s):  
A Joensen ◽  
E Schmidt ◽  
C Dethlefsen ◽  
A Tjonneland ◽  
L Rasmussen ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Dietary Intake ◽  
Docosapentaenoic Acid ◽  
Healthy Men ◽  
Coronary Syndrome

scholarly journals Estradiol Does Not Influence Lipid Measures and Inflammatory Markers in Testosterone-Clamped Healthy Men

2018 ◽  
Vol 2 (8) ◽  
pp. 882-892
Author(s):  
Ferdinand Roelfsema ◽  
Rebecca J Yang ◽  
Johannes D Veldhuis
Keyword(s):  
Inflammatory Markers ◽  
Healthy Men

scholarly journals Association of work-related and leisure-time physical activity with workplace food purchases, dietary quality, and health of hospital employees

2019 ◽  
Author(s):  
Emily Feig ◽  
Douglas E. Levy ◽  
Jessica L. McCurley ◽  
Eric B. Rimm ◽  
Emma M. Anderson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Dietary Intake ◽  
Leisure Time ◽  
Cardiometabolic Risk ◽  
Sedentary Time ◽  
Leisure Time Physical Activity ◽  
Healthy Eating Index ◽  
Hospital Employees ◽  
Work Related ◽  
High Work

Abstract Background While leisure-time physical activity (PA) has been associated with reduced risk of cardiometabolic disease, less is known about the relationship between work-related PA and health. Work-related PA is often not a chosen behavior and may be associated with lower socioeconomic status and less control over job-related activities. This study examined whether high work-related PA and leisure-time PA reported by hospital employees were associated with healthier dietary intake and reductions in cardiometabolic risk. Methods This was a cross-sectional analysis of baseline data collected from 602 hospital employees who used workplace cafeterias and enrolled in a health promotion study between 2016-2018. Participants completed the International Physical Activity Questionnaire and two 24-hour dietary recalls used to calculate Healthy Eating Index (HEI) scores. A Healthy Purchasing Score was calculated based on healthfulness of workplace food/beverage purchases. Weight, blood pressure, HbA1c, and lipids were measured. Regression analyses examined Healthy Purchasing Score, HEI, and obesity, hypertension, hyperlipidemia, and diabetes/prediabetes by quartile of work-related PA, leisure-time PA, and sedentary time. Results The mean age of participants was 43.6 years (SD = 12.2), 79.4% were female, and 81.1% were white. In total, 30.3% had obesity, 20.6% had hypertension, 26.6% had prediabetes/diabetes, and 32.1% had hyperlipidemia. Median leisure-time PA was 12.0 (IQR: 3.3, 28.0) and median work-related PA was 14.0 (IQR: 0.0, 51.1) MET-hours/week. Higher leisure-time PA was associated with higher workplace Healthy Purchasing Score and HEI (p’s < 0.01) and lower prevalence of obesity, diabetes/prediabetes, and hyperlipidemia (p’s < 0.05). Work-related PA was not associated with Healthy Purchasing Score, HEI, or cardiometabolic risk factors. Increased sedentary time was associated with lower HEI (p = 0.02) but was not associated with the workplace Healthy Purchasing Score. Conclusions Employees with high work-related PA did not have associated reductions in cardiometabolic risk or have healthier dietary intake as did employees reporting high leisure-time PA. Workplace wellness programs should promote leisure-time PA and healthy food choices for all employees, but programs may need to be customized and made more accessible to meet the unique needs of employees who are physically active at work.

scholarly journals Association of work-related and leisure-time physical activity with workplace food purchases, dietary quality, and health of hospital employees

2019 ◽  
Author(s):  
Emily Feig ◽  
Douglas E. Levy ◽  
Jessica L. McCurley ◽  
Eric B. Rimm ◽  
Emma M. Anderson ◽  
...  
Keyword(s):  
Physical Activity ◽  
Dietary Intake ◽  
Leisure Time ◽  
Cardiometabolic Risk ◽  
Sedentary Time ◽  
Leisure Time Physical Activity ◽  
Healthy Eating Index ◽  
Hospital Employees ◽  
Work Related ◽  
High Work

Abstract Background. While leisure-time physical activity (PA) has been associated with reduced risk of cardiometabolic disease, less is known about the relationship between work-related PA and health. Work-related PA is often not a chosen behavior and may be associated with lower socioeconomic status and less control over job-related activities. This study examined whether high work-related PA and leisure-time PA reported by hospital employees were associated with healthier dietary intake and reductions in cardiometabolic risk. Methods. This was a cross-sectional analysis of baseline data collected from 602 hospital employees who used workplace cafeterias and enrolled in a health promotion study between 2016-2018. Participants completed the International Physical Activity Questionnaire and two 24-hour dietary recalls used to calculate Healthy Eating Index (HEI) scores. A Healthy Purchasing Score was calculated based on healthfulness of workplace food/beverage purchases. Weight, blood pressure, HbA1c, and lipids were measured. Regression analyses examined Healthy Purchasing Score, HEI, and obesity, hypertension, hyperlipidemia, and diabetes/prediabetes by quartile of work-related PA, leisure-time PA, and sedentary time. Results. The mean age of participants was 43.6 years (SD = 12.2), 79.4% were female, and 81.1% were white. In total, 30.3% had obesity, 20.6% had hypertension, 26.6% had prediabetes/diabetes, and 32.1% had hyperlipidemia. Median leisure-time PA was 12.0 (IQR: 3.3, 28.0) and median work-related PA was 14.0 (IQR: 0.0, 51.1) MET-hours/week. Higher leisure-time PA was associated with higher workplace Healthy Purchasing Score and HEI (p’s < 0.01) and lower prevalence of obesity, diabetes/prediabetes, and hyperlipidemia (p’s < 0.05). Work-related PA was not associated with Healthy Purchasing Score, HEI, or cardiometabolic risk factors. Increased sedentary time was associated with lower HEI (p = 0.02) but was not associated with the workplace Healthy Purchasing Score. Conclusions. Employees with high work-related PA did not have associated reductions in cardiometabolic risk or have healthier dietary intake as did employees reporting high leisure-time PA. Workplace wellness programs should promote leisure-time PA and healthy food choices for all employees, but programs may need to be customized and made more accessible to meet the unique needs of employees who are physically active at work.

scholarly journals Associations of dietary intake with cardiometabolic risk in a multi-ethnic cohort: a longitudinal analysis of the Determinants of Adolescence, now young Adults, Social well-being and Health (DASH) study

2019 ◽  
Vol 121 (09) ◽  
pp. 1069-1079
Author(s):  
Louise M. Goff ◽  
Peiyuan Huang ◽  
Maria J. Silva ◽  
Claire Bordoli ◽  
Elli Z. Enayat ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Ethnic Groups ◽  
Young Adulthood ◽  
Cardiometabolic Risk ◽  
Well Being ◽  
Dietary Behaviour ◽  
Black African ◽  
Dietary Behaviours ◽  
Black Caribbean ◽  
Skipping Breakfast

AbstractUnfavourable dietary habits, such as skipping breakfast, are common among ethnic minority children and may contribute to inequalities in cardiometabolic disease. We conducted a longitudinal follow-up of a subsample of the UK multi-ethnic Determinants of Adolescent Social well-being and Health cohort, which represents the main UK ethnic groups and is now aged 21–23 years. We aimed to describe longitudinal patterns of dietary intake and investigate their impact on cardiometabolic risk in young adulthood. Participants completed a dietary behaviour questionnaire and a 24 h dietary intake recall; anthropometry, blood pressure, total cholesterol and HDL-cholesterol and HbA1c were measured. The cohort consisted of 107 White British, 102 Black Caribbean, 132 Black African, 98 Indian, 111 Bangladeshi/Pakistani and 115 other/mixed ethnicity. Unhealthful dietary behaviours such as skipping breakfast and low intake of fruits and vegetables were common (56, 57 and 63 %, respectively). Rates of skipping breakfast and low fruit and vegetable consumption were highest among Black African and Black Caribbean participants. BMI and cholesterol levels at 21–23 years were higher among those who regularly skipped breakfast at 11–13 years (BMI 1·41 (95 % CI 0·57, 2·26), P=0·001; cholesterol 0·15 (95 % CI –0·01, 0·31), P=0·063) and at 21–23 years (BMI 1·05 (95 % CI 0·22, 1·89), P=0·014; cholesterol 0·22 (95 % CI 0·06, 0·37), P=0·007). Childhood breakfast skipping is more common in certain ethnic groups and is associated with cardiometabolic risk factors in young adulthood. Our findings highlight the importance of targeting interventions to improve dietary behaviours such as breakfast consumption at specific population groups.

Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors

2019 ◽  
Vol 49 (10) ◽  
pp. 1749-1757 ◽  
Author(s):  
Ragni H. Mørch ◽  
Ingrid Dieset ◽  
Ann Færden ◽  
Elina J. Reponen ◽  
Sigrun Hope ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mental Disorders ◽  
T Cell Activation ◽  
Psychotropic Medication ◽  
Inflammatory Markers ◽  
Cardiometabolic Risk ◽  
Disease Risk ◽  
Interleukin 2 ◽  
Cardiometabolic Risk Factors ◽  
Severe Mental Disorders

AbstractBackgroundInflammation and immune activation have been implicated in the pathogenesis of severe mental disorders and cardiovascular disease (CVD). Despite high level of comorbidity, many studies of the immune system in severe mental disorders have not systematically taken cardiometabolic risk factors into account.MethodsWe investigated if inflammatory markers were increased in schizophrenia (SCZ) and affective (AFF) disorders independently of comorbid CVD risk factors. Cardiometabolic risk factors (blood lipids, body mass index and glucose) and CVD-related inflammatory markers CXCL16, soluble interleukin-2 receptor (sIL-2R), soluble CD14 (sCD14), macrophage inhibitory factor and activated leukocyte cell adhesion molecule (ALCAM) were measured inn= 992 patients (SCZ, AFF), andn= 647 healthy controls. We analyzed the inflammatory markers before and after controlling for comorbid cardiometabolic risk factors, and tested for association with psychotropic medication and symptom levels.ResultsCXCL16 (p= 0.03) and sIL-2R (p= 7.8 × 10−5) were higher, while sCD14 (p= 0.05) were lower in patients compared to controls after controlling for confounders, with significant differences in SCZ for CXCL16 (p= 0.04) and sIL-2R (p= 1.1 × 10−5). After adjustment for cardiometabolic risk factors higher levels of sIL-2R (p= 0.001) and lower sCD14 (p= 0.002) remained, also in SCZ (sIL-2R,p= 3.0 × 10−4and sCD14,p= 0.01). The adjustment revealed lower ALCAM levels (p= 0.03) in patients. We found no significant associations with psychotropic medication or symptom levels.ConclusionThe results indicate that inflammation, in particular enhanced T cell activation and impaired monocyte activation, are associated with severe mental disorders independent of comorbid cardiometabolic risk factors. This suggests a role of novel pathophysiological mechanisms in severe mental disorders, particularly SCZ.

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