Combination therapy of human adipose-derived stem cells and basic fibroblast growth factor hydrogel in muscle regeneration

Biomaterials ◽  
2013 ◽  
Vol 34 (25) ◽  
pp. 6037-6045 ◽  
Author(s):  
Ji Hye Hwang ◽  
In Gul Kim ◽  
Shuyu Piao ◽  
Ae Ryang Jung ◽  
Ji Young Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Growth Factor ◽  
Combination Therapy ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Muscle Regeneration ◽  
Adipose Derived Stem Cells ◽  
Fibroblast Growth

scholarly journals Noncultured Autologous Adipose-Derived Stem Cells Therapy for Chronic Radiation Injury

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Sadanori Akita ◽  
Kozo Akino ◽  
Akiyoshi Hirano ◽  
Akira Ohtsuru ◽  
Shunichi Yamashita
Keyword(s):  
Stem Cells ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Angiogenic Factor ◽  
Skin Defect ◽  
Adipose Derived Stem Cells ◽  
Fibroblast Growth ◽  
Chronic Radiation ◽  
Artificial Dermis

Increasing concern on chronic radiation injuries should be treated properly for life-saving improvement of wound management and quality of life. Recently, regenerative surgical modalities should be attempted with the use of noncultured autologous adipose-derived stem cells (ADSCs) with temporal artificial dermis impregnated and sprayed with local angiogenic factor such as basic fibroblast growth factor, and secondary reconstruction can be a candidate for demarcation and saving the donor morbidity. Autologous adipose-derived stem cells, together with angiogenic and mitogenic factor of basic fibroblast growth factor and an artificial dermis, were applied over the excised irradiated skin defect and tested for Patients who were uneventfully healed with minimal donor-site morbidity, which lasts more than 1.5 years.

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