The effect of inertial loading on wrist postural tremor in essential tremor

2009 ◽  
Vol 120 (5) ◽  
pp. 1020-1029 ◽  
Author(s):  
M.E. Héroux ◽  
G. Pari ◽  
K.E. Norman
Keyword(s):  
Essential Tremor ◽  
Postural Tremor ◽  
Inertial Loading

Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor

Neurology ◽  
2019 ◽  
Vol 93 (24) ◽  
pp. e2284-e2293 ◽  
Author(s):  
Casey H. Halpern ◽  
Veronica Santini ◽  
Nir Lipsman ◽  
Andres M. Lozano ◽  
Michael L. Schwartz ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Adverse Events ◽  
Essential Tremor ◽  
Focused Ultrasound ◽  
Rating Scale ◽  
Prospective Trial ◽  
Postural Tremor ◽  
Hand Tremor

ObjectiveTo test the hypothesis that transcranial magnetic resonance–guided focused ultrasound (tcMRgFUS) thalamotomy is effective, durable, and safe for patients with medication-refractory essential tremor (ET), we assessed clinical outcomes at 3-year follow-up of a controlled multicenter prospective trial.MethodsOutcomes were based on the Clinical Rating Scale for Tremor, including hand combined tremor–motor (scale of 0–32), functional disability (scale of 0–32), and postural tremor (scale of 0–4) scores, and total scores from the Quality of Life in Essential Tremor Questionnaire (scale of 0–100). Scores at 36 months were compared with baseline and at 6 months after treatment to assess for efficacy and durability. Adverse events were also reported.ResultsMeasured scores remained improved from baseline to 36 months (all p < 0.0001). Range of improvement from baseline was 38%–50% in hand tremor, 43%–56% in disability, 50%–75% in postural tremor, and 27%–42% in quality of life. When compared to scores at 6 months, median scores increased for hand tremor (95% confidence interval [CI] 0–2, p = 0.0098) and disability (95% CI 1–4, p = 0.0001). During the third follow-up year, all previously noted adverse events remained mild or moderate, none worsened, 2 resolved, and no new adverse events occurred.ConclusionsResults at 3 years after unilateral tcMRgFUS thalamotomy for ET show continued benefit, and no progressive or delayed complications. Patients may experience mild degradation in some treatment metrics by 3 years, though improvement from baseline remains significant.Clinicaltrials.gov identifierNCT01827904.Classification of evidenceThis study provides Class IV evidence that for patients with severe ET, unilateral tcMRgFUS thalamotomy provides durable benefit after 3 years.

scholarly journals Clinical Differentiation of Essential Tremor and Parkinson's Disease

2013 ◽  
Vol 6 ◽  
pp. CCRep.S11903 ◽  
Author(s):  
Robert Fekete ◽  
Jin Li
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Essential Tremor ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Postural Tremor ◽  
Arm Swing ◽  
Rest Tremor ◽  
Dopaminergic Terminal

We present clinical features and tremor characterization in a patient with Parkinson's disease (PD) as well as in two cases of essential tremor (ET) with some parkinsonian features but no evidence of dopaminergic terminal loss on 123I-FP-CIT Single Photon Emission Computed Tomography (SPECT). Relatively slow frequency rest tremor and bilateral upper extremity bradykinesia without decrementing amplitude were observed in the ET cases, with unilaterally decreased arm swing in case 3. Alternating rest tremor and re-emergent tremor with 13 second latency was confirmed in the PD case. Re-emergent tremor had alternating characteristics, which to our knowledge has not been previously reported. The ET cases had synchronous postural tremor. Alternating re-emergent tremor in PD provides further evidence for re-emergent tremor as an analogue of rest tremor in PD. Two cases of ET with synchronous postural tremor and one to two year history of parkinsonian features had no evidence of dopaminergic terminal loss up to 40 years after the initial onset of ET. Tremor synchronicity characterization can assist in differential diagnosis between the two disorders.

scholarly journals Correlates Between Force and Postural Tremor in Older Individuals with Essential Tremor

2015 ◽  
Vol 15 (6) ◽  
pp. 688-695 ◽  
Author(s):  
Justin J. Kavanagh ◽  
Justin W.L. Keogh
Keyword(s):  
Essential Tremor ◽  
Older Individuals ◽  
Postural Tremor

Combined resting-postural tremor of lower limbs: Another essential tremor variant

Neurology ◽  
1990 ◽  
Vol 40 (6) ◽  
pp. 1006-1006 ◽  
Author(s):  
A. Rapoport ◽  
I. Sarova ◽  
H. Braun
Keyword(s):  
Essential Tremor ◽  
Lower Limbs ◽  
Postural Tremor

scholarly journals Sensory electrical stimulation for suppression of postural tremor in patients with essential tremor

2015 ◽  
Vol 26 (s1) ◽  
pp. S803-S809 ◽  
Author(s):  
Jae-Hoon Heo ◽  
Ji-Won Kim ◽  
Yuri Kwon ◽  
Sang-Ki Lee ◽  
Gwang-Moon Eom ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Essential Tremor ◽  
Postural Tremor

Resetting of essential tremor and postural tremor in Parkinson's disease with transcranial magnetic stimulation

1994 ◽  
Vol 17 (7) ◽  
pp. 800-807 ◽  
Author(s):  
A. Pascual-Leone ◽  
J. Valls-Solé ◽  
C. Toro ◽  
E. M. Wassermann ◽  
M. Hallett
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Transcranial Magnetic Stimulation ◽  
Essential Tremor ◽  
Magnetic Stimulation ◽  
Postural Tremor

scholarly journals Quantitative measures of postural tremor at the upper limb joints in patients with essential tremor

2020 ◽  
Vol 28 ◽  
pp. 499-507
Author(s):  
Do-Young Kwon ◽  
Yu-Ri Kwon ◽  
Yoon-Hyeok Choi ◽  
Gwang-Moon Eom ◽  
Junghyuk Ko ◽  
...  
Keyword(s):  
Essential Tremor ◽  
Upper Limb ◽  
Postural Tremor

scholarly journals Medical Treatment of Essential Tremor

2014 ◽  
Vol 6 ◽  
pp. JCNSD.S13570 ◽  
Author(s):  
Ali H. Rajput ◽  
Alex Rajput
Keyword(s):  
Drug Treatment ◽  
Medical Treatment ◽  
Essential Tremor ◽  
Upper Limb ◽  
Postural Tremor ◽  
Alcoholic Drink ◽  
Kinetic Tremor ◽  
Effective Drugs ◽  
Pathological Tremor ◽  
Biochemical Abnormalities

Essential tremor (ET) is the most common pathological tremor characterized by upper limb action—postural tremor (PT)/kinetic tremor (KT). There are no specific neuropathological or biochemical abnormalities in ET. The disability is consequent to amplitude of KT, which may remain mild without handicap or may become disabling. The most effective drugs for sustained tremor control are propranolol and primidone. Symptomatic drug treatment must be individualized depending on the circumstances that provoke the tremor-related disability. Broad guidelines for treatment are discussed in this review. Patients may be treated intermittently only on stressful occasions with propranolol, clonazepam, or primidone monotherapy, or an alcoholic drink. Those with persistently disabling tremor need continued treatment.

Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study

2002 ◽  
Vol 17 (2) ◽  
pp. 313-316 ◽  
Author(s):  
Kevin C. Brennan ◽  
Eva C. Jurewicz ◽  
Blair Ford ◽  
Seth L. Pullman ◽  
Elan D. Louis
Keyword(s):  
Essential Tremor ◽  
Electrophysiological Study ◽  
Postural Tremor

scholarly journals Decoding voluntary movements and postural tremor based on thalamic LFPs as a basis for closed-loop stimulation for essential tremor

2019 ◽  
Vol 12 (4) ◽  
pp. 858-867 ◽  
Author(s):  
Huiling Tan ◽  
Jean Debarros ◽  
Shenghong He ◽  
Alek Pogosyan ◽  
Tipu Z. Aziz ◽  
...  
Keyword(s):  
Essential Tremor ◽  
Closed Loop ◽  
Voluntary Movements ◽  
Postural Tremor ◽  
Closed Loop Stimulation
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