Invariant temperature and field strain functions for Nb3Sn composite superconductors

Cryogenics ◽  
2006 ◽  
Vol 46 (12) ◽  
pp. 846-863 ◽  
Author(s):  
W. Denis Markiewicz
Author(s):  
Y.P. Manshin ◽  
◽  
E.Yu. Manshina ◽  

The article considers an algorithm for analyzing the results of field strain-measurement studies of machine structures, which allows obtaining data for the modernization of elements in the form of coefficients of parameter changes. As the object of application of the method, the design element of the header was selected, which had failures due to insufficient endurance under cyclic bending stresses.


Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 784
Author(s):  
Sylvia Reemers ◽  
Sander van Bommel ◽  
Qi Cao ◽  
David Sutton ◽  
Saskia van de Zande

Equine influenza virus (EIV) is a major cause of respiratory disease in horses. Vaccination is an effective tool for infection control. Although various EIV vaccines are widely available, major outbreaks occurred in Europe in 2018 involving a new EIV H3N8 FC1 strain. In France, it was reported that both unvaccinated and vaccinated horses were affected despite >80% vaccination coverage and most horses being vaccinated with a vaccine expressing FC1 antigen. This study assessed whether vaccine type, next to antigenic difference between vaccine and field strain, plays a role. Horses were vaccinated with an ISCOMatrix-adjuvanted, whole inactivated virus vaccine (Equilis Prequenza) and experimentally infected with the new FC1 outbreak strain. Serology (HI), clinical signs, and virus shedding were evaluated in vaccinated compared to unvaccinated horses. Results showed a significant reduction in clinical signs and a lack of virus shedding in vaccinated horses compared to unvaccinated controls. From these results, it can be concluded that Equilis Prequenza provides a high level of protection to challenge with the new FC1 outbreak strain. This suggests that, apart from antigenic differences between vaccine and field strain, other aspects of the vaccine may also play an important role in determining field efficacy.


Measurement ◽  
2021 ◽  
Vol 177 ◽  
pp. 109279
Author(s):  
Huachen Jiang ◽  
Chunfeng Wan ◽  
Kang Yang ◽  
Youliang Ding ◽  
Songtao Xue

2014 ◽  
Vol 17 (1) ◽  
pp. 3-8 ◽  
Author(s):  
J.S. Niczyporuk ◽  
G. Woźniakowski ◽  
H. Czekaj ◽  
E. Samorek-Salamonowicz

AbstractThe aim of the study was to determine the influence of adenovirus infection on the replication of Marek’s disease virus vaccine strain Rispens/CVI988 during in vitro co-infection studies. Adenovirus field strain JN-5/10j was isolated from sick chickens. The study was conducted in chicken embryo fibroblast cultures (CEF). Monolayers of CEFs were infected with Rispens strain and field adenovirus strain JN-5/10j with different doses (101.0-103.0TCID50) in the following manner: a) simultaneously, b) first, infection with Rispens strain and after 24 h infection with adenovirus strain JN-5/10j and c) infection with adenovirus strain JN-5/10j 24 h before infection with Rispens strain. After 18, 24, 48, 72, and 96 h of incubation, the copy number of the pp38 gene of Rispens strain was determined using Real-time PCR. The results indicated that the Adenovirus infection before the infection with Rispens strain reduced the replication of the pp38 gene after 48 h by 2 log10.


Author(s):  
Stefan Hartmann ◽  
Rose Rogin Gilbert

AbstractIn this article, we follow a thorough matrix presentation of material parameter identification using a least-square approach, where the model is given by non-linear finite elements, and the experimental data is provided by both force data as well as full-field strain measurement data based on digital image correlation. First, the rigorous concept of semi-discretization for the direct problem is chosen, where—in the first step—the spatial discretization yields a large system of differential-algebraic equation (DAE-system). This is solved using a time-adaptive, high-order, singly diagonally-implicit Runge–Kutta method. Second, to study the fully analytical versus fully numerical determination of the sensitivities, required in a gradient-based optimization scheme, the force determination using the Lagrange-multiplier method and the strain computation must be provided explicitly. The consideration of the strains is necessary to circumvent the influence of rigid body motions occurring in the experimental data. This is done by applying an external strain determination tool which is based on the nodal displacements of the finite element program. Third, we apply the concept of local identifiability on the entire parameter identification procedure and show its influence on the choice of the parameters of the rate-type constitutive model. As a test example, a finite strain viscoelasticity model and biaxial tensile tests applied to a rubber-like material are chosen.


2018 ◽  
Vol 28 (2) ◽  
pp. 1-5 ◽  
Author(s):  
Teruo Matsushita ◽  
Edmund S. Otabe ◽  
Dongho Kim ◽  
Taejong Hwang ◽  
Huixian Gao ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document