Concentrations in plasma, urinary excretion and bactericidal activity of levofloxacin (500mg) versus ciprofloxacin (500mg) in healthy volunteers receiving a single oral dose

2006 ◽  
Vol 28 (6) ◽  
pp. 551-559 ◽  
Author(s):  
Florian M.E. Wagenlehner ◽  
Martina Kinzig-Schippers ◽  
Fritz Sörgel ◽  
W. Weidner ◽  
Kurt G. Naber
Keyword(s):  
Oral Dose ◽  
Urinary Excretion ◽  
Healthy Volunteers ◽  
Single Oral Dose ◽  
Bactericidal Activity

scholarly journals Urinary Bactericidal Activity of Extended-Release Ciprofloxacin (1,000 Milligrams) versus Levofloxacin (500 Milligrams) in Healthy Volunteers Receiving a Single Oral Dose

2006 ◽  
Vol 50 (11) ◽  
pp. 3947-3949 ◽  
Author(s):  
Florian M. E. Wagenlehner ◽  
Martina Kinzig-Schippers ◽  
Uwe Tischmeyer ◽  
Christine Wagenlehner ◽  
Fritz Sörgel ◽  
...  
Keyword(s):  
Oral Dose ◽  
Healthy Volunteers ◽  
Single Oral Dose ◽  
Bactericidal Activity ◽  
Proteus Mirabilis ◽  
Extended Release

ABSTRACT Twelve volunteers received a single oral dose of 1,000 mg extended-release (XR) ciprofloxacin versus 500 mg levofloxacin to assess urinary bactericidal titers (UBTs) against common uropathogens. Areas under UBT-time curves were significantly larger for Proteus mirabilis with XR ciprofloxacin and for staphylococci with levofloxacin.

Urinary Pharmacokinetics and Bactericidal Activity of Finafloxacin (200 and 800 mg) in Healthy Volunteers Receiving a Single Oral Dose

Chemotherapy ◽  
2011 ◽  
Vol 57 (2) ◽  
pp. 97-107 ◽  
Author(s):  
Florian M.E. Wagenlehner ◽  
Christine M. Wagenlehner ◽  
Birgit Blenk ◽  
Holger Blenk ◽  
Sabine Schubert ◽  
...  
Keyword(s):  
Oral Dose ◽  
Healthy Volunteers ◽  
Single Oral Dose ◽  
Bactericidal Activity
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