Urinary Pharmacokinetics and Bactericidal Activity of Finafloxacin (200 and 800 mg) in Healthy Volunteers Receiving a Single Oral Dose

Chemotherapy ◽  
2011 ◽  
Vol 57 (2) ◽  
pp. 97-107 ◽  
Author(s):  
Florian M.E. Wagenlehner ◽  
Christine M. Wagenlehner ◽  
Birgit Blenk ◽  
Holger Blenk ◽  
Sabine Schubert ◽  
...  
Keyword(s):  
Oral Dose ◽  
Healthy Volunteers ◽  
Single Oral Dose ◽  
Bactericidal Activity

scholarly journals Urinary Bactericidal Activity of Extended-Release Ciprofloxacin (1,000 Milligrams) versus Levofloxacin (500 Milligrams) in Healthy Volunteers Receiving a Single Oral Dose

2006 ◽  
Vol 50 (11) ◽  
pp. 3947-3949 ◽  
Author(s):  
Florian M. E. Wagenlehner ◽  
Martina Kinzig-Schippers ◽  
Uwe Tischmeyer ◽  
Christine Wagenlehner ◽  
Fritz Sörgel ◽  
...  
Keyword(s):  
Oral Dose ◽  
Healthy Volunteers ◽  
Single Oral Dose ◽  
Bactericidal Activity ◽  
Proteus Mirabilis ◽  
Extended Release

ABSTRACT Twelve volunteers received a single oral dose of 1,000 mg extended-release (XR) ciprofloxacin versus 500 mg levofloxacin to assess urinary bactericidal titers (UBTs) against common uropathogens. Areas under UBT-time curves were significantly larger for Proteus mirabilis with XR ciprofloxacin and for staphylococci with levofloxacin.

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