scholarly journals P2-563: BRAIN WEIGHT AT AUTOPSY AMONG DEMENTED INDIVIDUALS IS PRIMARILY A MEASURE OF RESERVE, NOT ATROPHY: THE NUN STUDY

2019 ◽  
Vol 15 ◽  
pp. P838-P838
Author(s):  
James A. Mortimer ◽  
Amy R. Borenstein
Keyword(s):  
1998 ◽  
Vol 38 (4) ◽  
pp. 367-373
Author(s):  
Tohru SONODA ◽  
Keiichiro KONO ◽  
Naoya ITOKAZU ◽  
Tohru SUGIMOTO

2002 ◽  
Vol 90 (1) ◽  
pp. 236-238 ◽  
Author(s):  
Jože Balažic ◽  
Andrej Marušič

In 2000 we tested previously reported findings by Salib and Tadros that brain weight of fatal self-harm victims is higher than of those who died of natural causes. Our results were based on data from 15 suicides and 15 deaths of other causes. Data included matching variables of age, sex, time between death and postmortem examination, and temperature of the surrounding environment. The exploratory variables were brain weight and method of death. No significant difference was found between the brain weights of suicides and others. On the other hand, some differences were obtained for different suicide methods, which also differed in the temperature of the environment, this being lower for the group of suicides that occurred outdoors (around or below 0°C). Once we excluded all the outdoor cases and controls, a significantly higher brain weight was obtained for suicide cases. These and previous results are intriguing and require explanation. Respirator brain syndrome as described by Moseley, Molinari, and Walker in 1976 may provide only a partial explanation. Another possible suggestion is that higher brain weight in suicide victims may be related to previously demonstrated increased amygdala blood flow and subsequent amygdala enlargement due to the increased processing of emotional information.


1980 ◽  
Vol 238 (1) ◽  
pp. R76-R81 ◽  
Author(s):  
H. F. Cserr ◽  
M. Bundgaard ◽  
J. K. Ashby ◽  
M. Murray

The size of choroid plexuses and cerebral ventricles relative to brain varies widely among vertebrates. The functional significance of this variability has attracted little attention since Herrick's original proposal that large choroid plexuses might enhance oxygen delivery to the brain and therefore be of adaptive value in the transition of vertebrates from water to air breathing. We compared choroid plexus and brain weight or ventricular and brain volume in 40 species from nine vertebrate groups. Both choroid plexus weight and ventricular volume were unrelated to brain size. Plexus weight ranged from 0 to 5.2% of brain weight and ventricular volume from 0.9 to 132% of brain volume. Amid this diversity the dipnoans, chondrosteans, holosteans, amphibians, and crossopterygian examined in this study are exceptional in uniformly having large plexuses. The adaptive significance of large choroid plexuses may lie in the presence of specific homeostatic mechanisms and their role in the response to the increases in PCO2 that accompany the transition to air breathing.


1966 ◽  
Vol 19 (3) ◽  
pp. 675-681 ◽  
Author(s):  
Cynthia Wimer ◽  
Lee Prater

Learning ability, exploratory behavior, and emotionality were measured in mice genetically selected for high and low total brain weight. The high selection lines scored significantly higher than the low lines in locomotor activity in the open field and discrimination learning performance in a water maze, and these findings were supported by correlations between brain weight and behavioral scores within unselected control lines. There is some evidence that these behavioral differences are associated with general changes in brain size produced by genetic selection.


2017 ◽  
Vol 61 (4) ◽  
pp. 5-11 ◽  
Author(s):  
C. S. Ibe ◽  
S. O. Salami ◽  
N. Wanmi

Abstract As a sequel to the current advancement in ethology, this study was designed to provide information on the brain size of the African grasscutter at specific postnatal periods and to extrapolate these findings to the behaviour of the rodent in its natural habitat. Brain samples were extracted from African grasscutter neonates on postnatal day 6, juveniles on postnatal day 72 and adults on postnatal day 450 by basic neuro-anatomical techniques. The weight, volume and dimensions of the brain samples were determined in absolute and relative terms. Their encephalisation quotient was also computed. There was a very strong positive correlation between nose-rump length and brain length in the neonates. The relative brain weight of neonates, juveniles and adults were 3.84 ± 0.12 %, 2.49 ± 0.07 % and 0.44 ± 0.03 %, respectively. The differences were significant (P < 0.05). The encephalisation quotient of juveniles was 1.62 ± 0.03 while that of the adult was 0.49 ± 0.02. The difference was significant (P < 0.05). The results were extrapolated to the animal’s cognitive ability, and compared with other rodents. It was concluded that the juvenile African grasscutter may have higher cognitive ability than the adult rodent, thus, juveniles should be preferred in physiological studies of memory and cognition.


1980 ◽  
Vol 1 (5) ◽  
pp. 445-449 ◽  
Author(s):  
Hillary B. Katz ◽  
Christine A. Davies ◽  
John Dobbing

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