How Soon Does the Pain in the Treatment Site Disperse after Photodynamic Therapy Treatment for Superficial Skin Disease?

2015 ◽  
Vol 46 (1) ◽  
pp. S25
Author(s):  
Taeyoung Lee ◽  
Emily Sinclair
Keyword(s):  
Photodynamic Therapy ◽  
Skin Disease ◽  
Treatment Site ◽  
Superficial Skin ◽  
Therapy Treatment

Efficacy of the Topical ALA-Photodynamic Therapy for Superficial Skin Tumors

2009 ◽  
Vol 71 (2) ◽  
pp. 201-205
Author(s):  
Minako YASUMOTO ◽  
Takako SHIMODA ◽  
Rieko TSUBOUCHI ◽  
Seiji KAWANA
Keyword(s):  
Photodynamic Therapy ◽  
Skin Tumors ◽  
Superficial Skin

scholarly journals Targeted photodynamic therapy treatment of in vitro A375 metastatic melanoma cells

Oncotarget ◽  
2019 ◽  
Vol 10 (58) ◽  
pp. 6079-6095 ◽  
Author(s):  
Channay Naidoo ◽  
Cherie Ann Kruger ◽  
Heidi Abrahamse
Keyword(s):  
Photodynamic Therapy ◽  
Metastatic Melanoma ◽  
Melanoma Cells ◽  
Targeted Photodynamic Therapy ◽  
Therapy Treatment

scholarly journals 770Clinical results of photodynamic therapy for superficial skin malignancies or actinic keratosis using topical 5-aminolaevulinic acid

1996 ◽  
Vol 40 ◽  
pp. S196
Author(s):  
P.J.N. Meijnders ◽  
W.M. Star ◽  
R.S. de Bruijn ◽  
M.J.M. van Mierto ◽  
S.J.M. Wijthoff ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Actinic Keratosis ◽  
Aminolaevulinic Acid ◽  
Superficial Skin

scholarly journals Dual use of porphyrazines as sensitizers and viscosity markers in photodynamic therapy

2015 ◽  
Vol 3 (6) ◽  
pp. 1089-1096 ◽  
Author(s):  
M. Angeles Izquierdo ◽  
Aurimas Vyšniauskas ◽  
Svetlana A. Lermontova ◽  
Ilya S. Grigoryev ◽  
Natalia Y. Shilyagina ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Dual Function ◽  
Dual Use ◽  
Viscosity Measurements ◽  
Therapy Treatment

A dual-function photoactive macrocycle enables simultaneous viscosity measurements and photodynamic therapy treatment, allowing the monitoring of PDT progress by FLIM.

scholarly journals Comparison of Antibacterial Activity and Wound Healing in a Superficial Abrasion Mouse Model of Staphylococcus aureus Skin Infection Using Photodynamic Therapy Based on Methylene Blue or Mupirocin or Both

2021 ◽  
Vol 8 ◽  
Author(s):  
Montserrat Pérez ◽  
Pilar Robres ◽  
Bernardino Moreno ◽  
Rosa Bolea ◽  
Maria T. Verde ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Antimicrobial Activity ◽  
Wound Healing ◽  
Photodynamic Therapy ◽  
Skin Infection ◽  
Infection Model ◽  
Impaired Wound Healing ◽  
Superficial Skin ◽  
Histopathological Studies ◽  
Enhance Wound Healing

Background: Antibiotic resistance and impaired wound healing are major concerns in S. aureus superficial skin infections, and new therapies are needed. Antimicrobial photodynamic therapy (aPDT) is a new therapeutic approach for infections, but it also improves healing in many wound models.Objective: To compare the antimicrobial activity and the effects on wound healing of aPDT based on Methylene Blue (MB-aPDT) with mupirocin treatment, either alone or in combination, in superficial skin wounds of S. aureus-infected mice. Additionally, to evaluate the clinical, microbiological, and cosmetic effects on wound healing.Materials and Methods: A superficial skin infection model of S. aureus was established in SKH-1 mice. Infected wounds were treated with MB-aPDT, MB-aPDT with a daily topical mupirocin or only with mupirocin. No treatment was carried out in control animals. Daily clinical and microbiological examinations were performed until complete clinical wound healing. Histopathological studies and statistical analysis were performed at the end of the study.Results: MB-aPDT treatment induced the best wound healing compared to mupirocin alone or to mupirocin plus MB-aPDT. Superficial contraction at 24 h and a greater reduction in size at 48 h, quicker detachment of the crust, less scaling, and absence of scars were observed. Histopathological studies correlated with clinical and gross findings. By contrast, mupirocin showed the highest logaritmic reduction of S. aureus.Conclusions: MB-aPDT and mupirocin treatments are effective in a murine superficial skin infection model of S. aureus. One session of MB-aPDT was the best option for clinical wound healing and cosmetic results. The addition of mupirocin to MB-aPDT treatment improved antimicrobial activity; however, it did not enhance wound healing. No synergistic antibacterial effects were detected.

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