Bone quality characteristics obtained by Fourier transform infrared and Raman spectroscopic imaging

2017 ◽  
Vol 59 (3) ◽  
pp. 142-145 ◽  
Author(s):  
Hiromi Kimura-Suda ◽  
Teppei Ito
2003 ◽  
Vol 57 (4) ◽  
pp. 357-366 ◽  
Author(s):  
Rohit Bhargava ◽  
Ira W. Levin

Fourier transform infrared (FT-IR) imaging allows simultaneous spectral characterization of large spatial areas due to its multichannel detection advantage. The acquisition of large amounts of data in the multichannel configuration results, however, in a poor temporal resolution of sequentially acquired data sets, which limits the examination of dynamic processes to processes that have characteristic time scales of the order of minutes. Here, we introduce the concept and instrumental details of a time-resolved infrared spectroscopic imaging modality that permits the examination of repetitive dynamic processes whose half-lives are of the order of milliseconds. As an illustration of this implementation of step-scan FT-IR imaging, we examine the molecular responses to external electric-field perturbations of a microscopically heterogeneous polymer–liquid crystal composite. Analysis of the spectroscopic data using conventional univariate and generalized two-dimensional (2D) correlation methods emphasizes an additional capability for accessing of simultaneous spatial and temporal chemical measurements of molecular dynamic processes.


2016 ◽  
Vol 45 (7) ◽  
pp. 1850-1864 ◽  
Author(s):  
K. L. Andrew Chan ◽  
Sergei G. Kazarian

Recent advances and emerging applications of ATR-FTIR spectroscopic imaging for analysis of biomedical samples have been reviewed.


2001 ◽  
Vol 55 (8) ◽  
pp. 1079-1084 ◽  
Author(s):  
Rohit Bhargava ◽  
Michael D. Schaeberle ◽  
Daniel C. Fernandez ◽  
Ira W. Levin

2003 ◽  
Vol 107 (41) ◽  
pp. 11290-11301 ◽  
Author(s):  
Andrei Gromov ◽  
Denis Ostrovskii ◽  
Andreas Lassesson ◽  
Martin Jönsson ◽  
Eleanor E. B. Campbell

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