Gamma Co-60 ray irradiation synthesis of dextran stabilized selenium nanoparticles and their antioxidant activity

2018 ◽  
Vol 205 ◽  
pp. 29-34 ◽  
Author(s):  
Nguyen Quoc Hien ◽  
Phan Dinh Tuan ◽  
Dang Van Phu ◽  
Le Anh Quoc ◽  
Nguyen Thi Kim Lan ◽  
...  
Author(s):  
Jay Vyas ◽  
Shafkat Rana

Objective: The objective of this present study were to the biogenic synthesis of selenium nanoparticles using Aloe vera extract and check it’s antioxidant potential by ABTS, DPPH and FRAP assays.Methods: In this study we investigated the clove of Aloe vera, which is used for the synthesis of selenium nanoparticles were characterized by using UV-Visible (UV-VIS) spectrophotometer, Transmission electron microscopy (TEM), Fourier transform spectroscopy (FTIR) and Energy dispersive X-Ray spectroscopy (EDAX) and ABTS, DPPH and FRAP assays for checked it’s antioxidant potential.Results: The present study was carried out to synthesis of Selenium nanoparticles using extract of Aloe vera. UV-Vis Spectra at 350 nm with Aloe vera extract and observed as hollow and spherical particles in size ranging 7-48 nm which is found more stable more than two months. EDAX analysis was carried out to check the presoak of Selenium in nanoparticles. Results of EDAX, confirmed its present. TEM and SEAD represented addition evidence of formation of nanoparticles whereas SEAD indicates the particles were crystalline in nature. FT-IR analysis was carried out to identify the possible bio molecules and Aloe vera extract-metal ions interaction responsible for formation and stabilization of selenium nanoparticles. FRAP, ABTS and DPPH assay results sequester that Selenium nanoparticles prepared using Aloe vera extract possess more activity than extract alone.Conclusion: The bio molecules of Aloe veraextract acted as stabilizing as well as capping agent leading to the formation of Selenium nanoparticles. Selenite has been proven to have antioxidant activity and is being used as chemoprevention agent in cancer diagnosis but same time it is toxic also. Elemental Selenium i.e. Selenium nanoparticles are less toxic form of selenium. 


2020 ◽  
Vol 102 (10) ◽  
pp. 556-567
Author(s):  
Awanish Kumar ◽  
Bablu Prasad ◽  
Jayanand Manjhi ◽  
Kumar Suranjit Prasad

2020 ◽  
Vol 11 (4) ◽  
pp. 6221-6226
Author(s):  
Twinkle Francis ◽  
Preejitha V B ◽  
Rajeshkumar S

The nanoparticles are known to reduce toxicity, enhance bioactivity and improve targeting cells. The metal and metal oxide nanoparticles such as gold, silver, zinc oxide, zirconium oxide, copper oxide, copper sulfide, selenium, hydroxyl apatite, and titanium oxide were used in several biomedical applications especially diagnosis of cancer, etc. The selenium nanoparticles (SeNPs) are explored due toits unique characteristics and various known therapeutic benefits such as anti bacterial, anti fungal and anti cancer activities. The selenium nanoparticles actively involved in the free radical scavenging activity and anti inflammatory activity. The antioxidant activities and reducing risk of cancer.In this present study, Cynodondactylon or Bermuda grass mediated synthesis of selenium nanoparticles and it was characterized using UV- vis spectrophotometer. And its antioxidant effect was analysed using DPPH assay. The plant extract of Cynodondactylon was prepared using distilled water and mixed with the sodium selenite solution. The solution was kept in a magnetic stirrer at 100 RPM for constant stirring while being observed for any colour change. The results showed that there was a significant antioxidant activity and peak confirm the selenium nanoparticles formation. Finally we conclude that the selenium nanoparticles can be used in various drug designing aspects in future.


2020 ◽  
Vol 11 (4) ◽  
pp. 3020-3031 ◽  
Author(s):  
Lei Qiao ◽  
Xina Dou ◽  
Shuqi Yan ◽  
Baohua Zhang ◽  
Chunlan Xu

Biogenic SeNPs synthesized by Lactobacillus casei ATCC 393 reversed diquat-induced oxidative damage to the epithelium by activating the Nrf2 signaling pathway.


2012 ◽  
Vol 14 (11) ◽  
Author(s):  
S. K. Torres ◽  
V. L. Campos ◽  
C. G. León ◽  
S. M. Rodríguez-Llamazares ◽  
S. M. Rojas ◽  
...  

Author(s):  
P. S. Thana Lakshme ◽  
Preetha S ◽  
M. Jeevitha ◽  
S. Rajeshkumar

Background: Among the nanoparticles, selenium nanoparticles (SeNP) are one of the most extensively studied as Selenium has zero oxidation state, non toxic and biologically inert material. This is the reason why Selenium is considered as a major nanoparticulate. In this study SeNPs were extracted from the fruit of Capparis decidua which is a xerophytic small herb. Aim: The aim of the present study is to evaluate the cytotoxic effect and antioxidant capacity of selenium nanoparticles. Materials and Methods: In this study SeNPs were extracted from the fruit of Capparis decidua which is a xerophytic small herb. The cytotoxic effect of SeNPs was evaluated using Brine Shrimp assay and the antioxidant activity was determined using DPPH assay considering ascorbic acid as the standard. Results: From the study of this assay the shrimps introduced  into the well were almost alive in different concentrations and this indicates that there is no cytotoxicity in selenium nanoparticles. The percentage inhibition of Selenium nanoparticles in 10 µl was 15.4 0.1, 20 µl was 38.36 0.15, 30 µl was 45.3 0.1, 40 µl was 59.6 0.15 and 50 µl was 65.6  0.1. It can be inferred that percentage inhibition increases with increase in concentration but it was less when compared to the percentage inhibition of the standard. Conclusion: The selenium nanoparticles extracted from Capparis decidua do not have any cytotoxic effect on shrimps. The SeNPs possessed significant antioxidant activity in increasing concentrations compared to the standard used. Thus SeNPs are biologically useful and can be used as eco-friendly, cost effective and efficient biomedical agents and therapeutics.


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