Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naïve CD4 T cells to differentiate into Th2 cells

2007 ◽  
Vol 44 (14) ◽  
pp. 3580-3587 ◽  
Author(s):  
Tao Liu ◽  
Shao-Heng He ◽  
Peng-Yuan Zheng ◽  
Tao-Yuan Zhang ◽  
Bin-Quan Wang ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Cd4 T Cells ◽  
Staphylococcal Enterotoxin ◽  
Th2 Cells ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B ◽  
Human Dendritic Cells

Human Eosinophils Enhance Staphylococcal Enterotoxin B Stimulation of CD4+ T-cells

2006 ◽  
Vol 117 (2) ◽  
pp. S62
Author(s):  
S.K. Mathur ◽  
E.A. Durocher ◽  
L. Liu ◽  
E.A.B. Kelly ◽  
J.B. Sedgwick ◽  
...  
Keyword(s):  
T Cells ◽  
Cd4 T Cells ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B ◽  
Stimulation Of

Fas/Fas Ligand Interaction Regulates Cytotoxicity of CD4+T Cells against Staphylococcal Enterotoxin B-Pulsed Endothelial Cells

1997 ◽  
Vol 239 (3) ◽  
pp. 782-788 ◽  
Author(s):  
Satoshi Urayama ◽  
Atsushi Kawakami ◽  
Naoki Matsuoka ◽  
Masahiko Tsuboi ◽  
Tomoki Nakashima ◽  
...  
Keyword(s):  
T Cells ◽  
Endothelial Cells ◽  
Cd4 T Cells ◽  
Fas Ligand ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Ligand Interaction ◽  
Enterotoxin B

scholarly journals Age‐Related Increase in the Frequency of CD4+T Cells That Produce Interferon‐γ in Response to Staphylococcal Enterotoxin B during Childhood

2009 ◽  
Vol 200 (12) ◽  
pp. 1921-1927 ◽  
Author(s):  
Rima Hanna‐Wakim ◽  
Linda L. Yasukawa ◽  
Phillip Sung ◽  
Mimi Fang ◽  
Barbara Sullivan ◽  
...  
Keyword(s):  
T Cells ◽  
Cd4 T Cells ◽  
Interferon Γ ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Age Related ◽  
Enterotoxin B ◽  
Related Increase

scholarly journals Human Dendritic Cells Stimulated via TLR7 and/or TLR8 Induce the Sequential Production of Il-10, IFN-γ, and IL-17A by Naive CD4+ T Cells

2009 ◽  
Vol 182 (6) ◽  
pp. 3372-3379 ◽  
Author(s):  
Vincent Lombardi ◽  
Laurence Van Overtvelt ◽  
Stéphane Horiot ◽  
Philippe Moingeon
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Cd4 T Cells ◽  
Ifn Γ ◽  
Human Dendritic Cells

scholarly journals Memory T cells are anergic to the superantigen staphylococcal enterotoxin B.

1992 ◽  
Vol 176 (2) ◽  
pp. 575-579 ◽  
Author(s):  
W T Lee ◽  
E S Vitetta
Keyword(s):  
T Cells ◽  
Memory T Cells ◽  
Immune Deficiency Syndrome ◽  
Deficiency Syndrome ◽  
Staphylococcal Enterotoxin ◽  
Peripheral Tolerance ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B

We have used staphylococcal enterotoxin B (SEB) to study the role of naive and memory T cells in the induction of peripheral tolerance. After administration of SEB to mice, the numbers of naive and memory T cells increase, as does the proportion of memory T cells, which are unresponsive to further stimulation with SEB in vitro. In addition, memory T cells generated in response to conventional antigen, which proliferate and provide help to B cells in the presence of the conventional antigen, fail to respond to superantigen. Hence, memory T cells, in general, are anergized by SEB. These results suggest that SEB-induced activation and anergy reflect the combined responses of naive and memory T cells. The differential activation vs. anergy of naive and memory T cells by superantigen may be related to cytokine production and may play an important role in the etiology of autoimmune diseases or immunodeficiency diseases such as acquired immune deficiency syndrome.

Application of staphylococcal enterotoxin B on normal and atopic skin induces up-regulation of T cells by a superantigen-mediated mechanism

2000 ◽  
Vol 105 (4) ◽  
pp. 820-826 ◽  
Author(s):  
Lone Skov ◽  
Jeanett V. Olsen ◽  
Ralph Giorno ◽  
Patrick M. Schlievert ◽  
Ole Baadsgaard ◽  
...  
Keyword(s):  
T Cells ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Atopic Skin ◽  
Enterotoxin B
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