Antibacterial and antioxidant activity of cinnamon essential oil-laden 45S5 bioactive glass / soy protein composite scaffolds for the treatment of bone infections and oxidative stress

2021 ◽  
pp. 112320
Author(s):  
Irem Unalan ◽  
Tim Fuggerer ◽  
Benedikt Slavik ◽  
Andrea Buettner ◽  
Aldo R. Boccaccini
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Essential Oil ◽  
Bioactive Glass ◽  
Soy Protein ◽  
Composite Scaffolds ◽  
Bone Infections ◽  
Cinnamon Essential Oil ◽  
Antibacterial And Antioxidant Activity ◽  
And Oxidative Stress

scholarly journals Chemical Composition and Antibacterial and Antioxidant Activity of a Citrus Essential Oil and Its Fractions

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2888
Author(s):  
Carmen M. S. Ambrosio ◽  
Gloria L. Diaz-Arenas ◽  
Leidy P. A. Agudelo ◽  
Elena Stashenko ◽  
Carmen J. Contreras-Castillo ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antibacterial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Biological Activities ◽  
E Coli ◽  
Beneficial Bacterium ◽  
Minor Compounds ◽  
Antibacterial And Antioxidant Activity ◽  
High Relative Amount

Essential oils (EOs) from Citrus are the main by-product of Citrus-processing industries. In addition to food/beverage and cosmetic applications, citrus EOs could also potentially be used as an alternative to antibiotics in food-producing animals. A commercial citrus EO—Brazilian Orange Terpenes (BOT)—was fractionated by vacuum fractional distillation to separate BOT into various fractions: F1, F2, F3, and F4. Next, the chemical composition and biological activities of BOT and its fractions were characterized. Results showed the three first fractions had a high relative amount of limonene (≥10.86), even higher than the whole BOT. Conversely, F4 presented a larger relative amount of BOT’s minor compounds (carvone, cis-carveol, trans-carveol, cis-p-Mentha-2,8-dien-1-ol, and trans-p-Mentha-2,8-dien-1-ol) and a very low relative amount of limonene (0.08–0.13). Antibacterial activity results showed F4 was the only fraction exhibiting this activity, which was selective and higher activity on a pathogenic bacterium (E. coli) than on a beneficial bacterium (Lactobacillus sp.). However, F4 activity was lower than BOT. Similarly, F4 displayed the highest antioxidant activity among fractions (equivalent to BOT). These results indicated that probably those minor compounds that detected in F4 would be more involved in conferring the biological activities for this fraction and consequently for the whole BOT, instead of the major compound, limonene, playing this role exclusively.

scholarly journals Comparison of the Effects of Soy Protein and Whey Protein Supplementation during Exercise: a Systematic Review

2019 ◽  
Vol 21 (4) ◽  
pp. 397
Author(s):  
Suelen Maiara Medeiros da Silva ◽  
Bárbara Cristovão Carminati ◽  
Valfredo De Almeida Santos Junior ◽  
Pablo Christiano Barboza Lollo
Keyword(s):  
Oxidative Stress ◽  
Systematic Review ◽  
Protein Synthesis ◽  
Whey Protein ◽  
Lean Mass ◽  
Soy Protein ◽  
Mass Gain ◽  
Protein Supplementation ◽  
Protein Consumption ◽  
And Oxidative Stress

AbstractThe interest of the supplementation market for the soy protein consumption  to optimize physical and metabolic performance after exercise is increasing. However, evidence suggests that the  soy protein ingestion has lower anabolic properties when compared with whey protein. The purpose of this systematic review was to compare the effects of whey protein and soy protein supplementation on the  muscle functions maintenance after exercise. This review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Articles were searched for in the Pubmed database and included studies comparing the effects of soy protein and whey protein consumption on protein synthesis, lean mass gain and oxidative stress reduction in response to endurance or resistance training. Thirteen trials were included in this review. The results showed that the whey protein consumption is superior to that of soy protein with respect to protein synthesis and lean mass gain, but soy protein showed superior results in reducing oxidative stress. Future research comparing both soy and whey protein are needed to define protein source to be used in nutritional interventions to protein synthesis, lean mass gain and oxidative stress in different populations. Keywords: Soybean Proteins. Milk Proteins. Protein Biosynthesis. Hypertrophy. ResumoO interesse do mercado de suplementação pelo consumo de proteína de soja para otimizar o desempenho físico e metabólico após o exercício está aumentando. No entanto, evidências sugerem que a ingestão da proteína de soja tem propriedades anabólicas mais baixas quando comparada à proteína do soro do leite. O objetivo desta revisão sistemática foi comparar os efeitos da suplementação com whey protein e proteína de soja na manutenção das funções musculares após o exercício. Esta revisão foi realizada usando os Itens de Relatório Preferidos para Revisões Sistemáticas e Meta-Análises (PRISMA). Os artigos foram pesquisados na base de dados Pubmed e incluíram estudos comparando os efeitos da proteína de soja e do consumo de proteínas do soro na síntese protéica, ganho de massa magra e redução do estresse oxidativo em resposta ao treinamento de resistência ou resistência. Treze ensaios foram incluídos nesta revisão. Os resultados mostraram que o consumo de proteína de soro é superior ao da proteína de soja em relação à síntese protéica e ao ganho de massa magra, mas a proteína de soja apresentou resultados superiores na redução do estresse oxidativo. Pesquisas futuras comparando a soja e a proteína do soro do leite são necessárias para definir a fonte protéica a ser usada em intervenções nutricionais para a síntese protéica, ganho de massa magra e estresse oxidativo em diferentes populações. Palavras-chave: Proteínas de Soja. Proteínas do Leite. Biossíntese de Proteínas. Hipertrofia.

scholarly journals Chenopodium murale essential oil alleviates the genotoxicity and oxidative stress of silver nanoparticles in the rat kidney

2019 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Mossad Abdel-Wahhab ◽  
Helmy Ahmed ◽  
Aziza El-Nekeety ◽  
Sekena Abdel-Aziem ◽  
Hafiza Shara ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Silver Nanoparticles ◽  
Essential Oil ◽  
Rat Kidney ◽  
Chenopodium Murale ◽  
And Oxidative Stress

scholarly journals Biological Properties of a Citral-Enriched Fraction of Citrus limon Essential Oil

Foods ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1290
Author(s):  
Marzia Pucci ◽  
Stefania Raimondo ◽  
Chiara Zichittella ◽  
Vincenza Tinnirello ◽  
Valeria Corleone ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Essential Oil ◽  
Biological Activities ◽  
Protective Action ◽  
Biological Properties ◽  
Citrus Limon ◽  
Tnf Α ◽  
Pre Treatment ◽  
Flavoring Agent ◽  
And Oxidative Stress

Lemon essential oil (LEO) is a well-known flavoring agent with versatile biological activities. In the present study, we have isolated and characterized four citral-enriched fractions of winter LEO. We reported that in murine and human macrophages the pre-treatment with a mix of these fractions (Cfr-LEO) reduces the expression of the pro-inflammatory cytokines TNF-α, IL-1β, and IL-6 induced by LPS. In addition, Cfr-LEO counteracts LPS-induced oxidative stress, as shown by the increase in the GSH/GSSG ratio in comparison to cells treated with LPS alone. Overall, the results reported here encourage the application of EO fractions, enriched in citral, in the nutraceutical industry, not only for its organoleptic properties but also for its protective action against inflammation and oxidative stress.

scholarly journals Antidiabetes and Antioxidant agents from Clausena excavata root as medicinal plant of Myanmar

2019 ◽  
Vol 17 (1) ◽  
pp. 1339-1344 ◽  
Author(s):  
T. M. Thant ◽  
N. S. Aminah ◽  
A. N. Kristanti ◽  
R. Ramadhan ◽  
H. T. Aung ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Medicinal Plant ◽  
Type Ii Diabetes Mellitus ◽  
Positive Control ◽  
Hypoglycemic Agents ◽  
Dual Function ◽  
Oral Hypoglycemic Agents ◽  
Antioxidant Agents ◽  
And Oxidative Stress

AbstractAll around the world, patients with diabetes and the prevalence of its disease are currently growing. Due to these side effects of oral hypoglycemic agents and oxidative stress in complicating diabetes, there is growing interest in drugs, which possess dual function as both type II diabetes mellitus treatment and oxidative stress treatment. The objective of this research is to search effective antidiabetes and antioxidant bioactive compounds from the Myanmar medicinal plant Clausena excavata. The root part of C. excavata was successfully extracted with 95% ethanol and followed by column chromatographic separation technique. The structure of isolated pure compounds was elucidated by using methods of spectroscopic such as UV-Vis, IR, NMR and HRFABMS spectrometry. The α-glucosidase inhibition assay was performed against baker’s yeast and rat intestine (sucrose and maltase) α-glucosidases. The activity of isolated compounds’ antioxidant was measured by using DPPH assay. Among the tested enzymes, the two isolated compounds, which were dentatin (1) and heptaphylline (2), exhibited highest inhibitory on maltase enzymes with IC50 values 6.75 and 11.46 μM; as positive control, acarbose (IC50, 2.35 μM) was utilized. Moreover, scavenging activity was found to be present upon seeing the result of antioxidant activity investigation of (1) and (2) (IC50 values 2.66 and 1.55 mM), where ascorbic acid (IC50 0.012 mM) was used as standard. Both compounds showed their antidiabetic and antioxidant activity with different fashion, especially exhibited strongest activity against on maltase α-glucosidase.

Antioxidant activity and oxidative stress protection of duck proteins hydrolysates in SK-N-SH cells

2013 ◽  
Vol 4 (3) ◽  
pp. 476 ◽  
Author(s):  
Yuxing Guo ◽  
Daodong Pan ◽  
Zhen Wu ◽  
Chuanchuan Zhao ◽  
Jinxuan Cao
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Stress Protection ◽  
And Oxidative Stress ◽  
Oxidative Stress Protection
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