Acute toxicity of image-guided hypofractionated radiotherapy for prostate cancer: Nonrandomized comparison with conventional fractionation

2011 ◽  
Vol 29 (5) ◽  
pp. 523-532 ◽  
Author(s):  
Barbara Alicja Jereczek-Fossa ◽  
Dario Zerini ◽  
Cristiana Fodor ◽  
Luigi Santoro ◽  
Raffaella Cambria ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Hypofractionated Radiotherapy ◽  
Conventional Fractionation ◽  
Image Guided

Inverse Relationship Between Biochemical Outcome and Acute Toxicity After Image-Guided Radiotherapy for Prostate Cancer

2012 ◽  
Vol 83 (2) ◽  
pp. 608-616 ◽  
Author(s):  
Danny Vesprini ◽  
Charles Catton ◽  
Lindsay Jacks ◽  
Gina Lockwood ◽  
Tara Rosewall ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Inverse Relationship ◽  
Image Guided Radiotherapy ◽  
Image Guided

S87 Image guided radiotherapy (IGRT) in stage III prostate cancer: analysis of acute toxicity

2009 ◽  
Vol 8 (8) ◽  
pp. 636-637
Author(s):  
E. Mazzeo ◽  
G. Mantini ◽  
V. Frascino ◽  
G.C. Mattiucci ◽  
N. Dinapoli ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Stage Iii ◽  
Image Guided Radiotherapy ◽  
Image Guided

scholarly journals OC-0417: Acute toxicity with helical image guided IMRT for prostate cancer: hypofractionated versus conventional regimes

2015 ◽  
Vol 115 ◽  
pp. S202
Author(s):  
A.M. Bates ◽  
J.E. Scaife ◽  
M. Romanchikova ◽  
O. Young ◽  
A. Styling ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Image Guided

Acute toxicity and its dosimetric correlates for high-risk prostate cancer treated with moderately hypofractionated radiotherapy

2017 ◽  
Vol 42 (1) ◽  
pp. 18-23 ◽  
Author(s):  
Moses Arunsingh ◽  
Indranil Mallick ◽  
Sriram Prasath ◽  
B. Arun ◽  
Sandip Sarkar ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Acute Toxicity ◽  
Hypofractionated Radiotherapy ◽  
High Risk Prostate Cancer ◽  
Risk Prostate Cancer

Acute toxicity in hypofractionated radiotherapy for prostate cancer

2013 ◽  
Vol 18 ◽  
pp. S311-S312
Author(s):  
C. de Haro Bueno ◽  
J. Reinoso Cobo ◽  
M. Martos Alcalde ◽  
J. García Madueño ◽  
J. Richarte Reina ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Hypofractionated Radiotherapy

Acute toxicity of image-guided hypofractionated proton therapy for localized prostate cancer

2017 ◽  
Vol 23 (2) ◽  
pp. 353-360 ◽  
Author(s):  
Koichiro Nakajima ◽  
Hiromitsu Iwata ◽  
Hiroyuki Ogino ◽  
Yukiko Hattori ◽  
Shingo Hashimoto ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Acute Toxicity ◽  
Proton Therapy ◽  
Localized Prostate Cancer ◽  
Image Guided

scholarly journals Review of Hypofractionated Radiotherapy for Prostate Cancer

ISRN Oncology ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Despina Spyropoulou ◽  
Dimitrios Kardamakis
Keyword(s):  
Prostate Cancer ◽  
Large Fraction ◽  
Prostate Gland ◽  
Intensity Modulated Radiation Therapy ◽  
Conformal Radiotherapy ◽  
Convincing Evidence ◽  
External Beam Radiation ◽  
Hypofractionated Radiotherapy ◽  
Beam Radiation ◽  
Conventional Fractionation

Hypofractionated radiotherapy for prostate cancer has become of increasing interest with the recognition of a potential improvement in therapeutic outcome with treatments delivered in large-sized daily fractions. In addition, hypofractionation offers a reduction in fraction number and produces attractive cost and increased convenience for patients. There is convincing evidence, by several clinical trials, that biochemical control is significantly improved with higher administered radiation doses to the prostate gland. Furthermore, the improved radiation delivery techniques such as 3D conformal radiotherapy (3DCRT) or, better, intensity modulated radiation therapy (IMRT) allow high administered doses to the prostate while sparing the normal surrounding tissues. Several studies of the radiobiology of prostate cancer suggest that it may be more susceptible to large fraction sizes compared with conventional fractionation of external beam radiation.

scholarly journals Image-Guided Hypofractionated Radiotherapy in Low-Risk Prostate Cancer Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Maurizio Valeriani ◽  
Alessia Carnevale ◽  
Linda Agolli ◽  
Paolo Bonome ◽  
Adelaide Montalto ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Late Toxicity ◽  
Low Risk ◽  
Hypofractionated Radiotherapy ◽  
Low Grade ◽  
Image Guided ◽  
Gu Toxicity ◽  
Risk Prostate Cancer ◽  
Low Risk Prostate Cancer

Aim. To evaluate efficacy and toxicity of image-guided hypofractionated radiotherapy (HFRT) in the treatment of low-risk prostate cancer. Outcomes and toxicities of this series of patients were compared to another group of 32 low-risk patients treated with conventional fractionation (CFRT).Methods. Fifty-nine patients with low-risk prostate cancer were analysed. Total dose for the prostate and proximal seminal vesicles was 60 Gy delivered in 20 fractions.Results. The median follow-up was 30 months. The actuarial 4-year overall survival, biochemical free survival, and disease specific survival were 100%, 97.4%, and 97.4%, respectively. Acute grade 1-2 gastrointestinal (GI) and genitourinary (GU) toxicity rates were 11.9% and 40.7%, respectively. Grade 1 GI and GU late toxicity rates were 8.5% and 13.6%, respectively. No grade ≥2 late toxicities were recorded. Acute grade 2-3 GU toxicity resulted significantly lower (P=0.04) in HFRT group compared to the CFRT group. The cumulative 4-year incidence of grade 1-2 GU toxicity was significantly higher (P<0.001) for HFRT patients.Conclusions. Our study demonstrated that hypofractionated regimen provided excellent biochemical control in favorable risk prostate cancer patients. The incidence of GI and GU toxicity was low. However, HFRT presented higher cumulative incidence of low-grade late GU toxicity than CFRT.

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