Analysis of the risk of shunt failure or infection related to cerebrospinal fluid cell count, protein level, and glucose levels in low-birth-weight premature infants with posthemorrhagic hydrocephalus

2011 ◽  
Vol 2011 ◽  
pp. 270-271
Author(s):  
P. Klimo
Keyword(s):  
Cerebrospinal Fluid ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Cell Count ◽  
Premature Infants ◽  
Protein Level ◽  
Shunt Failure ◽  
Posthemorrhagic Hydrocephalus ◽  
Glucose Levels ◽  
Fluid Cell

Analysis of the risk of shunt failure or infection related to cerebrospinal fluid cell count, protein level, and glucose levels in low-birth-weight premature infants with posthemorrhagic hydrocephalus

2011 ◽  
Vol 7 (2) ◽  
pp. 147-151 ◽  
Author(s):  
Daniel H. Fulkerson ◽  
Shobhan Vachhrajani ◽  
Bradley N. Bohnstedt ◽  
Neal B. Patel ◽  
Akash J. Patel ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Red Blood Cells ◽  
Premature Infants ◽  
Blood Cells ◽  
White Blood Cells ◽  
Shunt Infection ◽  
Shunt Failure ◽  
Shunt Insertion ◽  
Posthemorrhagic Hydrocephalus

Object Premature, low-birth-weight infants with posthemorrhagic hydrocephalus have a high risk of shunt obstruction and infection. Established risk factors for shunt failure include grade of the hemorrhage and age at shunt insertion. There is anecdotal evidence that the amount of red blood cells or protein levels in the CSF may affect shunt performance. However, this has not been analyzed specifically for this cohort of high-risk patients. Therefore, the authors performed this study to examine whether any statistical relationship exists between the CSF constituents and the rate of shunt malfunction or infection in this population. Methods A retrospective cohort study was performed on premature infants born at Riley Hospital for Children from 2000 to 2009. Inclusion criteria were a CSF sample analyzed within 2 weeks prior to shunt insertion, low birth weight (< 1500 grams), prematurity (birth prior to 37 weeks estimated gestational age), and shunt insertion for posthemorrhagic hydrocephalus. Data points included the gestational age at birth and shunt insertion, weight at birth and shunt insertion, history of CNS infection prior to shunt insertion, shunt failure, shunt infection, and the levels of red blood cells, white blood cells, protein, and glucose in the CSF. Statistical analysis was performed to determine any association between shunt outcome and the CSF parameters. Results Fifty-eight patients met the study entry criteria. Ten patients (17.2%) had primary shunt failure within 3 months of insertion. Nine patients (15.5%) had shunt infection within 3 months. A previous CNS infection prior to shunt insertion was a statistical risk factor for shunt failure (p = 0.0290) but not for shunt infection. There was no statistical relationship between shunt malfunction or infection and the CSF levels of red blood cells, white blood cells, protein, or glucose before shunt insertion. Conclusions Low-birth-weight premature infants with posthemorrhagic hydrocephalus have a high rate of shunt failure and infection. The authors did not find any association of shunt failure or infection with CSF cell count, protein level, or glucose level. Therefore, it may not be useful to base the timing of shunt insertion on CSF parameters.

Use of external drainage for posthemorrhagic hydrocephalus in very low birth weight premature infants

1997 ◽  
Vol 13 (7) ◽  
pp. 369-374 ◽  
Author(s):  
Erwin Cornips ◽  
Frank Van Calenbergh ◽  
C. Plets ◽  
Hugo Devlieger ◽  
Paul Casaer
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Very Low Birth Weight ◽  
External Drainage ◽  
Posthemorrhagic Hydrocephalus

Transfusion-associated necrotising enterocolitis in very low birth weight premature infants

2012 ◽  
Vol 22 (5) ◽  
pp. 332-337 ◽  
Author(s):  
G. Demirel ◽  
I. H. Celik ◽  
H. T. Aksoy ◽  
O. Erdeve ◽  
S. S. Oguz ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Very Low Birth Weight ◽  
Necrotising Enterocolitis

scholarly journals Effects of Poverty on Home Environment: An Analysis of Three-Year Outcome Data for Low Birth Weight Premature Infants

1996 ◽  
Vol 21 (3) ◽  
pp. 419-431 ◽  
Author(s):  
Janine E. Watson ◽  
Russell S. Kirby ◽  
Kelly J. Kelleher ◽  
Robert H. Bradley
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Home Environment ◽  
Premature Infants ◽  
Outcome Data

Fungal Infections in Premature Infants

PEDIATRICS ◽  
1984 ◽  
Vol 74 (3) ◽  
pp. 443-443
Author(s):  
JILL E. BALEY ◽  
ROBERT M. KLIEGMAN ◽  
AVROY A. FANAROFF
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Glucose Tolerance ◽  
Glucose Intolerance ◽  
Premature Infants ◽  
Glucose Control ◽  
Fungal Infections ◽  
Low Birth Weight Infant ◽  
Multiple Factors ◽  
Glucose Intake

In Reply.— Seventy percent of the low-birth-weight (LBW) infants whose condition was clinically diagnosed as systemic fungal infections demonstrated glucose intolerance. Langdon is correct that hyperglycemia, which may be found in young diabetic women, may encourage nonsystemic or local candidiasis. He is also correct that multiple factors may affect glucose tolerance in the sick low-birth-weight infant. Whereas it is possible that alterations in care or glucose intake might result in hyperglycemia, it is unusual for a low-birth-weight infant who has previously demonstrated stable glucose control to suddenly develop hyperglycemia and/or glycosuria at 5 weeks of age.

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