Robotic surgery has the potential to revolutionize the field of surgery and improve patient safety. However, despite the advantages robotic surgery can offer, there are multiple human factors-related issues that may prevent these systems from realizing their full benefit. This study identified some of the salient human factors issues and considerations that need to be addressed for integration of new technologies such as robotic systems into the Operating Room of the future. We conducted in-depth interviews with operating team members and other stakeholders who have experience with robotic surgery to identify workflow, teamwork, training, and other clinical acceptance issues. Addressing these and other human factors issues will help the integration of surgical robotic systems into use for the ultimate goal of improving patient safety and healthcare quality.