Family history of peptic ulcer and a positive 13C urea breath test are predictive of gastroduodenal ulcer disease in uninvestigated dyspeptic patients

1998 ◽  
Vol 114 ◽  
pp. A59
Author(s):  
A. Armuzzi ◽  
M. Anti ◽  
C. Catananti ◽  
M.E. Lippi ◽  
M. Covino ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Yangchun Zhu ◽  
Xiaoying Zhou ◽  
Junbei Wu ◽  
Jing Su ◽  
Guoxin Zhang

Aim. The aim of this study was to investigate the prevalence and risk factors ofH. pyloriinfection in areas with high prevalence of gastric cancer in Jiangsu Province, China.Methods. A prospective epidemiologic survey ofH. pyloriinfection was accomplished in a natural population of 5417 individuals in Yangzhong city. Questionnaires and 13C-urea breath test forH. pyloriinfection were performed.Results. Among 5417 subjects who completed questionnaires and 13C-urea breath test, 3435 (63.41%) wereH. pyloripositive. The prevalence reached a peak at the age of 30–39 years (90.82%). There was significant difference between sexes and women had a higher infection rate than men. The prevalence ofH. pyloriinfection was also associated with eating kipper food and fried food. No association betweenH. pyloriprevalence and smoking or drinking was found. Compared to healthy individuals, people with dyspeptic diseases (peptic ulcer, gastroenteritis) presented a high prevalence ofH. pyloriinfection. Using multivariate logistic regression analysis, age and history of peptic ulcer and gastroenteritis were the independent predictors forH. pyloriinfection.Conclusions. Yangzhong city had a high prevalence ofH. pyloriinfection and was related to several risk factors. The underlying mechanisms are needed to be further investigated.


2011 ◽  
Vol 57 (1) ◽  
pp. 8 ◽  
Author(s):  
Ju Hyun Oak ◽  
Woo Chul Chung ◽  
Sung Hoon Jung ◽  
Kang Hyun Choi ◽  
Eun Jung Kim ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 121-124
Author(s):  
Mian Mashhud Ahmed ◽  
Atia Saeed ◽  
Abu Shams Md Hasan Ali Masum ◽  
Md Mohiuddin ◽  
Anisur Rahman

Background: Helicobacter pylori (HP) infection is an important cause of peptic ulcer disease (PUD) in the world. This study was aimed to know the trend of H.P. infection among the symptomatic subjects Method: This was a retrospective observational study conducted from January 2015 to July 2018 in three different hospitals in Dhaka city. Patient who presented with dyspepsia underwent 13C urea breath test. Positive cases were analyzed. Results: A total 1343 patients were taken for UBT where 308 (23%) patients were found positive. The mean age group was 41.21+13.6. Male were more infected (61%) than female (39%). Conclusion: Improving sanitary and hygienic condition of this region along with significantly increasing HP eradication therapy and PPI use by the symptomatic individuals might have contributed to the decreasing trend of infection Anwer Khan Modern Medical College Journal Vol. 10, No. 2: July 2019, P 121-124


1998 ◽  
Vol 44 (2) ◽  
pp. 293-298 ◽  
Author(s):  
Wayne H Schrier ◽  
Ronald J Schoengold ◽  
Josefina T Baker ◽  
Joyce L Norell ◽  
Corey L Jaseph ◽  
...  

Abstract We describe a solid-phase immunochromatographic serologic test, FlexSure® HP, to detect IgG antibodies against Helicobacter pylori. H. pylori colonize the stomach and proximal duodenum, cause ulcer disease and mucosa-associated lymphoid tissue lymphoma, and have a role in the development of other disorders, including gastric adenocarcinoma. FlexSure HP consists of a test strip, conjugate pad, and absorbent pad, in a novel reverse-flow chromatography format. In these studies, FlexSure HP was demonstrated to be specific for IgG antibodies against H. pylori. The reactive cutoff of the test was consistent with [13C]urea breath test and commercially available ELISAs. FlexSure HP had 94% sensitivity, 88% specificity, and 91% accuracy relative to [13C]urea breath test; and 95% sensitivity, 94% specificity, and 95% overall agreement relative to high-molecular-mass cell-associated protein enzyme immunoassay (HM-CAP EIA). FlexSure HP is a simple-to-perform, visually read test requiring no specialized training, equipment, or instrumentation, and yields rapid, accurate, qualitative results.


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