scholarly journals Cloning, baculovirus expression, and characterization of the alpha subunit of prolyl 4-hydroxylase from the nematode Caenorhabditis elegans. This alpha subunit forms an active alpha beta dimer with the human protein disulfide isomerase/beta subunit.

1994 ◽  
Vol 269 (43) ◽  
pp. 26746-26753
Author(s):  
J Veijola ◽  
P Koivunen ◽  
P Annunen ◽  
T Pihlajaniemi ◽  
K I Kivirikko
Keyword(s):  
Caenorhabditis Elegans ◽  
Protein Disulfide Isomerase ◽  
Beta Subunit ◽  
Alpha Subunit ◽  
Nematode Caenorhabditis Elegans ◽  
Disulfide Isomerase ◽  
Baculovirus Expression ◽  
Alpha Beta ◽  
Protein Disulfide

scholarly journals Nuclear magnetic resonance characterization of the N-terminal thioredoxin-like domain of protein disulfide isomerase

1995 ◽  
Vol 4 (12) ◽  
pp. 2587-2593 ◽  
Author(s):  
Johan Kemmink ◽  
Nigel J. Darby ◽  
Thomas E. Creighton ◽  
Klaas Dijkstra ◽  
Ruud M. Scheek
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Protein Disulfide Isomerase ◽  
Disulfide Isomerase ◽  
Protein Disulfide ◽  
Nuclear Magnetic

Mercury weakens membrane anchoring of Na-K-ATPase

1992 ◽  
Vol 262 (5) ◽  
pp. F837-F842 ◽  
Author(s):  
E. Imesch ◽  
M. Moosmayer ◽  
B. M. Anner
Keyword(s):  
Atpase Activity ◽  
Model Compound ◽  
Beta Subunit ◽  
Alpha Subunit ◽  
Structural Effects ◽  
Subunit Interaction ◽  
Alpha Beta ◽  
Membrane Anchoring ◽  
Atpase Inhibition

The presence of circulating inhibitors able to decrease the renal Na-K-adenosinetriphosphatase (ATPase) activity (natriuretic hormones) was postulated some 30 years ago. In the present work, the natriuretic inhibitor HgCl2 was selected as a model compound for the structural characterization of a possible natriuretic pathway for Na-K-ATPase modification. The structural effects of Na-K-ATPase inhibition by HgCl2 were assessed by trypsinolysis of the blocked enzyme in comparison with untreated preparations. The results show that inactivation of Na-K-ATPase by HgCl2 leads to the release of the alpha-subunit from the membrane preferentially in the E2 conformation but also in the E1 conformation. Apparently, HgCl2 weakens the membrane anchoring of the alpha-subunit, presumably by loosening the alpha-beta-subunit interaction. By this mechanism, the sensitivity of the Na-K-ATPase to extracellular drugs, hormones, and antibodies, as well as to intracellular proteases and other regulatory factors, could be altered.

Cloning and characterization of wheat PDI (protein disulfide isomerase) homoeologous genes and promoter sequences

Gene ◽  
2006 ◽  
Vol 366 (2) ◽  
pp. 209-218 ◽  
Author(s):  
M. Ciaffi ◽  
A.R. Paolacci ◽  
E. D'Aloisio ◽  
O.A. Tanzarella ◽  
E. Porceddu
Keyword(s):  
Protein Disulfide Isomerase ◽  
Disulfide Isomerase ◽  
Promoter Sequences ◽  
Homoeologous Genes ◽  
Protein Disulfide

scholarly journals Characterization of Aminobenzylphenols as Protein Disulfide Isomerase Inhibitors in Glioblastoma Cell Lines

2020 ◽  
Vol 63 (18) ◽  
pp. 10263-10286 ◽  
Author(s):  
Andrea Shergalis ◽  
Ding Xue ◽  
Fatma Z. Gharbia ◽  
Hannah Driks ◽  
Binita Shrestha ◽  
...  
Keyword(s):  
Cell Lines ◽  
Protein Disulfide Isomerase ◽  
Glioblastoma Cell ◽  
Disulfide Isomerase ◽  
Protein Disulfide ◽  
Glioblastoma Cell Lines

Characterization of Aspergillus fumigatus protein disulfide isomerase family gene

Gene ◽  
2001 ◽  
Vol 281 (1-2) ◽  
pp. 143-150 ◽  
Author(s):  
Shailly Nigam ◽  
P.V.G.K Sarma ◽  
P.C Ghosh ◽  
P.Usha Sarma
Keyword(s):  
Aspergillus Fumigatus ◽  
Protein Disulfide Isomerase ◽  
Disulfide Isomerase ◽  
Family Gene ◽  
Protein Disulfide ◽  
Protein Disulfide Isomerase Family
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