Journal of Medicinal Chemistry
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34499
(FIVE YEARS 2019)

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259
(FIVE YEARS 12)

Published By American Chemical Society

1520-4804, 0022-2623
Latest Documents Most Cited Documents Contributed Authors Related Sources Related Keywords

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1

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Author(s):  
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Jung-Eun Park ◽  
Young Jin Ham ◽  
Daniel C. Lim ◽  
Nicholas P. Kwiatkowski ◽  
...  

Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma

2022 ◽  
Author(s):  
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Zhibin Yang ◽  
Yanan Chen ◽  
Zhongren Xu ◽  
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Keyword(s):  
Hepatocellular Carcinoma ◽  
Cell Death ◽  
Immunogenic Cell Death

Development of Radiohalogenated Osimertinib Derivatives as Imaging Probes for Companion Diagnostics of Osimertinib

2022 ◽  
Author(s):  
Kenji Mishiro ◽  
Ryuichi Nishii ◽  
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Tomoki Sofuku ◽  
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Keyword(s):  
Companion Diagnostics ◽  
Imaging Probes

Systematic Variation of Both the Aromatic Cage and Dialkyllysine via GCE-SAR Reveal Mechanistic Insights in CBX5 Reader Protein Binding

2022 ◽  
Author(s):  
Kelsey M. Kean ◽  
Stefanie A. Baril ◽  
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Keyword(s):  
Protein Binding ◽  
Systematic Variation ◽  
Aromatic Cage

A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes

2022 ◽  
Author(s):  
Huarui Cui ◽  
Anand Divakaran ◽  
Zachariah J. Hoell ◽  
Mikael O. Ellingson ◽  
Cole R. Scholtz ◽  
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Keyword(s):  
Design Approach ◽  
Chemical Probes ◽  
High Affinity ◽  
Selective Chemical

Elastase Inhibitor Cyclotheonellazole A: Total Synthesis and In Vivo Biological Evaluation for Acute Lung Injury

2022 ◽  
Author(s):  
Yingjun Cui ◽  
Mengyi Zhang ◽  
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Tingrong Zhang ◽  
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Keyword(s):  
Acute Lung Injury ◽  
Lung Injury ◽  
Total Synthesis ◽  
Biological Evaluation ◽  
Elastase Inhibitor
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