Primary Adenocarcinoma of the Seminal Vesicles

2002 ◽  
Vol 168 (5) ◽  
pp. 1891-1896 ◽  
Author(s):  
RALF THIEL ◽  
PETER EFFERT
Keyword(s):  
Seminal Vesicles ◽  
Primary Adenocarcinoma

Primary adenocarcinoma of the seminal vesicles - a phantom tumour

2011 ◽  
Vol 83 (6) ◽  
pp. 356-360 ◽  
Author(s):  
K. Stamatiou ◽  
P. Sfikakis ◽  
S. Kontostolis ◽  
H. Moschouris ◽  
A. Z. Sermpetzoglou
Keyword(s):  
Seminal Vesicles ◽  
Primary Adenocarcinoma

scholarly journals An unusual cause of hematospermia: Primary adenocarcinoma of the seminal vesicle

2012 ◽  
Vol 6 (6) ◽  
pp. 259 ◽  
Author(s):  
Alper Eken ◽  
Volkan Izol ◽  
I. Atilla Aridogan ◽  
Seyda Erdogan ◽  
Arbil Acikalin ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Current Literature ◽  
Seminal Vesicles ◽  
Primary Adenocarcinoma

Adenocarcinoma of the seminal vesicles is one of the rare causes of hematospermia. Primary seminal vesicle adenocarcinoma is extremely rare and difficult to diagnose due to frequent invasion of adenocarcinomas of the surrounding organs, especially the prostate. In the present study, a case of a primary seminal vesicle adenocarcinoma will be discussed in the light of the current literature.

scholarly journals Primary adenocarcinoma of the seminal vesicles – Case report

2016 ◽  
Vol 27 (2) ◽  
pp. S57-S58
Author(s):  
Po-Chao Tsai ◽  
Yi-Hisen Chen ◽  
Chung-Jing Wang ◽  
Chien-Hsing Chang
Keyword(s):  
Case Report ◽  
Seminal Vesicles ◽  
Primary Adenocarcinoma

Primary Adenocarcinoma of the Seminal Vesicles: A Very Rare Neoplasia Occurring in a 56-Year-Old Patient

2017 ◽  
Vol 15 (1) ◽  
pp. e127-e129 ◽  
Author(s):  
Ioannis Katafigiotis ◽  
Panagiotis Mitsos ◽  
Georgios Kousournas ◽  
Stavros Sfoungaristos ◽  
Konstantinos Stravodimos ◽  
...  
Keyword(s):  
Seminal Vesicles ◽  
Primary Adenocarcinoma

scholarly journals Primary adenocarcinoma of the seminal vesicles. A review of the literature

2016 ◽  
Vol 88 (1) ◽  
pp. 47 ◽  
Author(s):  
Ioannis Katafigiotis ◽  
Stavros Sfoungaristos ◽  
Mordechai Duvdevani ◽  
Panagiotis Mitsos ◽  
Eleni Roumelioti ◽  
...  
Keyword(s):  
Specific Antigen ◽  
Digital Rectal Examination ◽  
Seminal Vesicles ◽  
Primary Adenocarcinoma ◽  
Ca 125 ◽  
Pet Ct ◽  
Magnetic Resonance Imaging Mri ◽  
Fdg Pet Ct ◽  
Specific Symptoms

Primary adenocarcinoma of the seminal vesicles (SV) are extremely rare and approximately only 60 cases have been reported in the literature. Due to the lack of specific symptoms the patients often present in an advanced stage of their disease. The only clinical examination that can indicate the presence of a neoplasm in the SVs is the digital rectal examination (DRE). Serum prostatic specific antigen (PSA) and prostate specific acid phosphatase (PAP) are usually normal in patients with primary adenocarcinoma of the SV and only CA-125 can be proved a useful blood biomarker contributing to the diagnosis and the follow up of the SV adenocarcinoma. Computed tomography (CT) and magnetic resonance imaging (MRI) and FDG-PET/CT have been used for the diagnosis and the staging of the SV adenocarcinoma. Various combinations of radical surgery, radiotherapy androgen deprivation therapy and chemotherapy have been proposed for the management of the disease but the prognosis is poor and the mean survival is two years after the diagnosis.

Primary adenocarcinoma of the seminal vesicles: a phantom tumor

2012 ◽  
Vol 38 (1) ◽  
pp. 48-51
Author(s):  
Stavros I. Tyritzis ◽  
Konstantinos Stamatiou ◽  
Adamantia Zizi-Sermpetzoglou ◽  
Andreas Skolarikos
Keyword(s):  
Seminal Vesicles ◽  
Primary Adenocarcinoma

Electron Microscopic Study of the Epithelium of the Seminal Vesicle of Aging Rats

1974 ◽  
Vol 32 ◽  
pp. 138-139
Author(s):  
V. F. Allison ◽  
G. C. Fink ◽  
G. W. Cearley
Keyword(s):  
Cell Growth ◽  
Epithelial Cell ◽  
Epithelial Cells ◽  
Seminal Vesicle ◽  
Seminal Vesicles ◽  
Epithelial Layer ◽  
Epithelial Hyperplasia ◽  
Electron Microscopic ◽  
Aging Rats ◽  
Pseudostratified Epithelium

It is well known that epithelial hyperplasia (benign hypertrophy) is common in the aging prostate of dogs and man. In contrast, little evidence is available for abnormal epithelial cell growth in seminal vesicles of aging animals. Recently, enlarged seminal vesicles were reported in senescent mice, however, that enlargement resulted from increased storage of secretion in the lumen and occurred concomitant to epithelial hypoplasia in that species.The present study is concerned with electron microscopic observations of changes occurring in the pseudostratified epithelium of the seminal vescles of aging rats. Special attention is given to certain non-epithelial cells which have entered the epithelial layer.

METABOLISM AND MODE OF ACTION OF ANDROGENS IN TARGET TISSUES OF MALE RATS

1972 ◽  
Vol 69 (1) ◽  
pp. 165-173 ◽  
Author(s):  
H. Schmidt ◽  
I. Noack ◽  
K. D. Voigt
Keyword(s):  
Cell Proliferation ◽  
Cell Metabolism ◽  
Seminal Vesicles ◽  
Male Rats ◽  
Ventral Prostate ◽  
Nucleic Acid Content ◽  
The Difference ◽  
Independent Effects ◽  
Sites Of Action ◽  
Peripheral Metabolism

ABSTRACT The effect of testosterone and 5α-dihydrotestosterone on protein and nucleic acid content as well as on the activities of some enzymes has been studied in the ventral prostate and the seminal vesicles of immature castrated rats. Both androgens were given intraperitoneally in doses of 1 mg daily for one or three days the rats were sacrificed one day after the last injection. In the prostate it was found that 5α-dihydrotestosterone had a greater effect on DNA increase, i. e. cell proliferation than testosterone, whereas cell metabolism was stimulated by the two androgens to nearly the same extent. In the seminal vesicles a single dose led to the same results as had been obtained in the prostate, i. e. a greater cell proliferative action of 5α-dihydrotestosterone and an equal stimulation of cell metabolism by testosterone and 5α-dihydrotestosterone was also observed. When three doses of the two androgens were given, cell proliferation as well as cell metabolism in the seminal vesicles were significantly more increased after 5α-dihydrotestosterone than after testosterone. The difference of action after systemic administration of the two androgens is explained by their different accumulation and by their different peripheral metabolism in the target tissues. From the partly independent effects of various androgens on cell proliferation and cell metabolism the conclusion may be drawn that there exist at least two intracellular sites of action.

REGULATION OF THE ACTIVITIES OF THE ENZYMES INVOLVED IN THE METABOLISM OF STEROID HORMONES IN RAT LIVER: THE EFFECT OF 19-NORTESTOSTERONE AND THE INFLUENCE OF CYPROTERONE ACETATE ON THE ACTION OF TESTOSTERONE AND 5α-DIHYDROTESTOSTERONE

1974 ◽  
Vol 77 (2) ◽  
pp. 287-297 ◽  
Author(s):  
Rüdiger Ghraf ◽  
Edmund Rodney Lax ◽  
Hanns-Georg Hoff ◽  
Herbert Schriefers
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Rat Liver ◽  
Enzyme Activities ◽  
Cyproterone Acetate ◽  
Hydroxysteroid Dehydrogenase ◽  
Seminal Vesicles ◽  
Normal Male ◽  
Steroid Hydroxylases ◽  
Drug Leads

ABSTRACT The androgens testosterone and 5α-dihydrotestosterone, the anabolic drug 19-nortestosterone and the anti-androgen cyproterone acetate were investigated with regard to their modifying action on the sexual differentiation of the activities of rat liver enzymes involved in steroid hormone metabolism. The activities of the enzymes (Δ4-5α-hydrogenase, 20-ketoreductase, 3α-and 3β-hydroxysteroid dehydrogenase, NAD- and NADP-dependent Δ4-3β-hydroxysteroid dehydrogenase, total steroid hydroxylases, 7α- and 16α-hydroxylase) were determined in cell-free liver fractions of male animals castrated on day 25 of life and killed on day 90; and of castrated animals which, from day 75 to 89 received daily sc injections (0.3 mg/100 g body weight) of the anabolic drug or the androgen only or in combination with cyproterone acetate (3 mg/100 g body weight). With the exception of 7α-hydroxylase castration leads to a feminization of the enzyme activity pattern. However, the degree of feminization varies from enzyme to enzyme. The administration of testosterone or of 5α-dihydrotestosterone reverses the effect of castration. With 5α-dihydrotestosterone activity values were reached which in some cases were significantly higher than those obtained with testosterone. Although both androgens restored the enzyme activities to the normal male values, neither androgen was able to compensate for the weight loss of the seminal vesicles in the dose administered. The administration of 19-nortestosterone in the same dose as testosterone is only 30 % as effective in restoring the weight loss of the seminal vesicles, but leads to identical activities of Δ4-5α-hydrogenase and of hydroxysteroid dehydrogenases as are found for testosterone. 19-Nortestosterone is without influence on the activities of total steroid hydroxylases and of 16α-hydroxylase. 16α-Hydroxylase is the only enzyme in which the activity enhancing effects of testosterone or of 5α-dihydrotestosterone can be completely blocked by the simultaneous administration of the anti-androgen cyproterone acetate. In all other enzyme activities the anti-androgen does not interfere with the effect of the androgens although it blocks their action on the weight restitution of the seminal vesicles by 60–70 %. 7α-Hydroxylase does not exhibit any androgen dependency. Neither castration nor the subsequent administration of the two androgens, or of the anabolic drug leads to any alterations in activity. However, it is interesting to note that the administration of cyproterone acetate does cause an increase in activity.

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