DETECTION OF INTERMITTENT ACUTE PORPHYRIA TRAIT IN CHILDREN

The Lancet ◽  
1976 ◽  
Vol 308 (7978) ◽  
pp. 201-202 ◽  
Author(s):  
Yves Nordmann ◽  
Bernard Grandchamp ◽  
Mireille Grelier ◽  
N'Guyen Phung ◽  
Hubert De Verneuil
Author(s):  
Cándido Alcázar López ◽  
Gonzalo P. Rodríguez Laiz ◽  
Rosario Sánchez Martínez ◽  
Sonia Pascual Bartolome ◽  
José Manuel Ramia

1985 ◽  
Vol 31 (10) ◽  
pp. 1673-1676 ◽  
Author(s):  
H P Monteiro ◽  
D S Abdalla ◽  
A S Arcuri ◽  
E J Bechara

Abstract We evaluated superoxide dismutase (EC 1.15.1.1) and glutathione peroxidase (EC 1.11.1.9) activities in the erythrocytes of lead-exposed and nonexposed workers from distinct industries localized in the State of São Paulo, Brazil. Concentrations of either lead or protoporphyrin IX, or both, in blood were used to indicate the extent of exposure. In all cases, values for superoxide dismutase were significantly higher in the exposed workers. The dose-response relationship between this enzyme and lead concentrations was roughly linear for the workers with greater than 40 micrograms of lead per 100 g of blood. Except for the sample from one of the industries, the corresponding glutathione peroxidase activities were also significantly higher in lead-exposed workers. These data, together with those previously found for patients with intermittent acute porphyria, suggest that in both groups the accumulation of heme precursors is connected to the exacerbated production of activated oxygen species.


1957 ◽  
Vol 256 (7) ◽  
pp. 309-311 ◽  
Author(s):  
Robert N. Monaco ◽  
Robert D. Leeper ◽  
Jacob J. Robbins ◽  
George L. Calvy

1972 ◽  
Vol 51 (10) ◽  
pp. 2530-2536 ◽  
Author(s):  
L. James Strand ◽  
Urs A. Meyer ◽  
Bertram F. Felsher ◽  
Allan G. Redeker ◽  
Harvey S. Marver

1977 ◽  
Vol 54 (5) ◽  
pp. 473-474 ◽  
Author(s):  
J. Teuber ◽  
F. Druschky ◽  
W. Franzke ◽  
H.W. Baenkler

The Lancet ◽  
1976 ◽  
Vol 307 (7954) ◽  
pp. 303
Author(s):  
PeterV. Tishler ◽  
DanielJ. Knighton ◽  
HenryM. Schumaker

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