Kinetics of cellular and cytokine responses in a chimeric mouse model for the study of staphylococcal enterotoxin B pathogenesis

2000 ◽  
Vol 71 (1) ◽  
pp. 19-26 ◽  
Author(s):  
Liang Yuan ◽  
George H Lowell ◽  
David L Hoover ◽  
C.A Colleton ◽  
Craig A Hammack ◽  
...  
Keyword(s):  
Mouse Model ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Chimeric Mouse ◽  
Cytokine Responses ◽  
Chimeric Mouse Model ◽  
Enterotoxin B ◽  
Kinetics Of

scholarly journals Inhibition of squamous cancer growth in a mouse model by Staphylococcal enterotoxin B-triggered Th9 cell expansion

2015 ◽  
Vol 14 (4) ◽  
pp. 371-379 ◽  
Author(s):  
Bei-Ping Miao ◽  
Rui-Shi Zhang ◽  
Huan-Ji Sun ◽  
Yan-Ping Yu ◽  
Tao Chen ◽  
...  
Keyword(s):  
Mouse Model ◽  
Cell Expansion ◽  
Staphylococcal Enterotoxin ◽  
Cancer Growth ◽  
Staphylococcal Enterotoxin B ◽  
Squamous Cancer ◽  
Enterotoxin B ◽  
Th9 Cell

Thermal Inactivation and Subsequent Reactivation of Staphylococcal Enterotoxin B in Selected Liquid Foods

1976 ◽  
Vol 39 (8) ◽  
pp. 516-520 ◽  
Author(s):  
CHARLOTTE A. REICHERT ◽  
DANIEL Y. C. FUNG
Keyword(s):  
Food Systems ◽  
Thermal Inactivation ◽  
Heating Time ◽  
Staphylococcal Enterotoxin ◽  
Diffusion Method ◽  
Staphylococcal Enterotoxin B ◽  
Enterotoxin B ◽  
Phosphate Buffered Saline ◽  
Kinetics Of ◽  
Gel Diffusion

Thermal inactivation and reactivation kinetics of staphylococcal enterotoxin B (SEB) were studied in buffer and certain liquid food systems using three serological techniques (single-gel diffusion method, radioimmunoassay, and microslide). Heating temperatures were 80–100 C and times were 0–5 min. Initial toxin concentrations employed were 0.008–5 μg/ml. Inactivation of SEB was faster in the earlier stages of heating and was much slower during continued heating. With the exception of phosphate buffered saline, reactivation of heated SEB was observed even when with small initial quantities of SEB. Reactivation (% activity) was greater when the heating time was shorter at any temperature.

scholarly journals Dexamethasone Attenuates Staphylococcal Enterotoxin B-Induced Hypothermic Response and Protects Mice from Superantigen-Induced Toxic Shock

2006 ◽  
Vol 50 (1) ◽  
pp. 391-395 ◽  
Author(s):  
Teresa Krakauer ◽  
Marilyn Buckley
Keyword(s):  
Mouse Model ◽  
Virulence Factors ◽  
Food Poisoning ◽  
Staphylococcal Enterotoxin ◽  
Induced Hypothermia ◽  
Staphylococcal Enterotoxin B ◽  
Toxic Shock ◽  
Inflammatory Agent ◽  
Hypothermic Response ◽  
Enterotoxin B

ABSTRACT The superantigenic staphylococcal enterotoxins are important virulence factors and contribute to various diseases, including food poisoning and toxic shock. Dexamethasone, an anti-inflammatory agent, attenuated staphylococcal enterotoxin B (SEB)-induced hypothermia and serum proinflammatory cytokines and improved survival from 0% to 86% in a lethal mouse model of SEB-mediated shock.

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