scholarly journals Dexamethasone Attenuates Staphylococcal Enterotoxin B-Induced Hypothermic Response and Protects Mice from Superantigen-Induced Toxic Shock

2006 ◽  
Vol 50 (1) ◽  
pp. 391-395 ◽  
Author(s):  
Teresa Krakauer ◽  
Marilyn Buckley
Keyword(s):  
Mouse Model ◽  
Virulence Factors ◽  
Food Poisoning ◽  
Staphylococcal Enterotoxin ◽  
Induced Hypothermia ◽  
Staphylococcal Enterotoxin B ◽  
Toxic Shock ◽  
Inflammatory Agent ◽  
Hypothermic Response ◽  
Enterotoxin B

ABSTRACT The superantigenic staphylococcal enterotoxins are important virulence factors and contribute to various diseases, including food poisoning and toxic shock. Dexamethasone, an anti-inflammatory agent, attenuated staphylococcal enterotoxin B (SEB)-induced hypothermia and serum proinflammatory cytokines and improved survival from 0% to 86% in a lethal mouse model of SEB-mediated shock.

scholarly journals Inhibition of squamous cancer growth in a mouse model by Staphylococcal enterotoxin B-triggered Th9 cell expansion

2015 ◽  
Vol 14 (4) ◽  
pp. 371-379 ◽  
Author(s):  
Bei-Ping Miao ◽  
Rui-Shi Zhang ◽  
Huan-Ji Sun ◽  
Yan-Ping Yu ◽  
Tao Chen ◽  
...  
Keyword(s):  
Mouse Model ◽  
Cell Expansion ◽  
Staphylococcal Enterotoxin ◽  
Cancer Growth ◽  
Staphylococcal Enterotoxin B ◽  
Squamous Cancer ◽  
Enterotoxin B ◽  
Th9 Cell

scholarly journals Detection of Staphylococcal Enterotoxin B in Milk and Milk Products Using Immunodiagnostic Lateral Flow Devices

2010 ◽  
Vol 93 (2) ◽  
pp. 569-575 ◽  
Author(s):  
Thomas Boyle ◽  
Joyce M Njoroge ◽  
Robert L Jones ◽  
Maryann Principato
Keyword(s):  
Capillary Flow ◽  
Food Poisoning ◽  
Ice Cream ◽  
Extraction Methods ◽  
Etiologic Agent ◽  
Staphylococcal Enterotoxin ◽  
Lateral Flow ◽  
Staphylococcal Enterotoxin B ◽  
Hook Effect ◽  
Enterotoxin B

Abstract Staphylococcal enterotoxin B (SEB) is an extracellular pyrotoxin produced by Staphylococcus aureus, a known etiologic agent of food poisoning in humans. Lateral flow immunochromatographic devices (LFDs) designed for the environmental detection of SEB were adapted for use in this study to detect SEB in milk containing 2 fat, chocolate-flavored milk, and milk-derived products such as yogurt, infant formula, and ice cream. The advantage of using LFDs in these particular food products was its ease and speed of use with no additional extraction methods needed. No false positives were observed with any of the products used in this study. Dilution of the samples overcame the Hook effect and permitted capillary flow into the membrane. Thus, semisolid products such as ice cream and some yogurts, and products containing thickeners needed to be diluted using a phosphate-buffered saline-based buffer, pH 7.2. SEB was easily detected at concentrations of 5 g/mL and 500 ng/mL when the LFDs were used. SEB was also reliably detected at concentrations below 5 and 0.25 ng/mL, which may induce serious disease.

Murine Lethal Toxic Shock Caused by Intranasal Administration of Staphylococcal Enterotoxin B

2003 ◽  
Vol 31 (4) ◽  
pp. 373-378 ◽  
Author(s):  
Vladimir Savransky ◽  
Victor Rostapshov ◽  
Dmitriy Pinelis ◽  
Yury Polotsky ◽  
Sergey Korolev ◽  
...  
Keyword(s):  
Intranasal Administration ◽  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Toxic Shock ◽  
Enterotoxin B

scholarly journals Murine Models of Staphylococcal Enterotoxin B-Induced Toxic Shock

2010 ◽  
Vol 175 (11) ◽  
pp. 917-922 ◽  
Author(s):  
Teresa Krakauer ◽  
Marilyn Buckley ◽  
Diana Fisher
Keyword(s):  
Staphylococcal Enterotoxin ◽  
Staphylococcal Enterotoxin B ◽  
Murine Models ◽  
Toxic Shock ◽  
Enterotoxin B
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