Risks of hepatocellular carcinoma and cirrhosis-associated complications in patients with rheumatoid arthritis receiving biologics: A 10-year population-based propensity-score matched cohort study

2018 ◽  
Vol 68 ◽  
pp. S445
Author(s):  
C.-S. Hsu ◽  
H.-C. Lang ◽  
H.H. Lin ◽  
Y.-C. Chao ◽  
C.-L. Chen
Keyword(s):  
Rheumatoid Arthritis ◽  
Hepatocellular Carcinoma ◽  
Cohort Study ◽  
Propensity Score ◽  
Population Based ◽  
Matched Cohort ◽  
Matched Cohort Study

scholarly journals Variant-of-concern-attributable health and health system-related outcomes: a population-level propensity-score matched cohort study

2021 ◽  
Author(s):  
Aysegul Erman ◽  
Sharmistha Mishra ◽  
Kali Barrett ◽  
Stephen Mac ◽  
David MJ Naimark ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Health Systems ◽  
Wild Type Strain ◽  
Severe Disease ◽  
Population Level ◽  
Population Based ◽  
Matched Cohort ◽  
Matched Cohort Study ◽  
Incident Laboratory

Background: As the transmission of SARS-CoV-2 variants intensifies globally, the burden of COVID-19 on the already strained health systems is becoming increasingly concerning. While there is growing literature on the effects of various variants-of-concern (VOC) on increased transmission, the extent to which VOCs may lead to more severe disease remains debated. Methods: In the current analysis, we use a population-based propensity-score matched cohort study of all incident laboratory-confirmed COVID-19 cases with VOC testing in Ontario, Canada to estimate healthcare resource use and health outcomes attributable to VOCs introduced to Ontario between January 1 and April 9, 2021, relative to the previously circulating wild-type strain. Results: We find that VOCs are associated with a higher odds of hospitalisation (odds ratio [OR], 2.25; 95% confidence interval [CI], 2.10-2.40) and ICU admission (OR, 3.31; 95%CI, 2.84-3.86); as well as with a higher odds of mortality for both the general COVID-19 population (OR 1.75; 1.47-2.09) and hospitalised cases (OR, 1.62; 95%CI, 1.23-2.15). Conclusion: Taken together, these findings suggest that health systems may face increased demand for healthcare resources as VOCs predominate worldwide in view of low global vaccination coverage.

scholarly journals Mortality Risk Associated with Haloperidol Use Compared with Other Antipsychotics: An 11-Year Population-Based Propensity-Score-Matched Cohort Study

CNS Drugs ◽  
2020 ◽  
Vol 34 (2) ◽  
pp. 197-206 ◽  
Author(s):  
Kim S. J. Lao ◽  
Angel Y. S. Wong ◽  
Ian C. K. Wong ◽  
Frank M. C. Besag ◽  
W. C. Chang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Propensity Score ◽  
Mortality Risk ◽  
Population Based ◽  
Matched Cohort ◽  
Matched Cohort Study
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