Responses to submaximal treadmill exercise and training in the horse: Changes in haematology, arterial blood gas and acid base measurements, plasma biochemical values and heart rate

1985 ◽  
Vol 5 (1) ◽  
pp. 56
1987 ◽  
Vol 252 (6) ◽  
pp. R1143-R1151
Author(s):  
H. J. Mangalam ◽  
D. R. Jones ◽  
A. M. Lacombe

The extreme elevation in plasma levels of free norepinephrine (NE) and free epinephrine (EP), which occurs during forced diving of ducks (Anas platyrhynchos), was studied before and after denervation of the adrenal glands. In intact animals both NE and EP concentration increased by up to two orders of magnitude in a 4-min dive but by a significantly lesser amount if the duck breathed O2 before the dive. Denervating the adrenal glands reduced the amounts of both catecholamines (CA) released during dives, plasma EP decreased to 10%, and NE to 50% of values obtained before denervation. Breathing O2 before a dive virtually eliminated CA release in denervates, indicating that hypoxia was the important non-neural releasing agent. Hypoxia was also the most important neural releasing agent compared with hypercapnia, acidosis, or hypoglycemia. Adrenal denervation did not cause significant changes in heart rate, blood pressure, arterial blood gas tensions, pH, or plasma glucose during dives, although denervation caused increased variation in some of these variables. In ducks CA release in dives is largely due to decreasing arterial O2 partial pressure, and full expression of the response is dependent on intact innervation of the adrenal gland.


2011 ◽  
Vol 24 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Amy L. Dzierba ◽  
Prasad Abraham

Acid−base disorders are common in the critically ill. Arterial blood gas (ABG) analysis is frequently used to identify and manage acid−base disturbances. Using a systematic problem-solving approach to acid−base disturbances will facilitate the identification and assess the progression and severity of the metabolic and respiratory abnormality. The intent of this review is to examine acid−base physiology and regulation, provide a method to evaluate a patient’s acid−base disorder, and provide therapeutic interventions.


1996 ◽  
Vol 88 (3) ◽  
pp. 347-350 ◽  
Author(s):  
G HANKINS ◽  
S CLARK ◽  
C HARVEY ◽  
E UCKAN ◽  
D COTTON ◽  
...  

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