Abstract #623 Refractory Thyroid Storm - Role of Single Pass Albumin Dialysis

2019 ◽  
Vol 25 ◽  
pp. 322-323
Author(s):  
Tanvi Parikh
Keyword(s):  
Thyroid Storm ◽  
Albumin Dialysis ◽  
Single Pass

scholarly journals SUN-559 Refractory Thyroid Storm: Role of Single Pass Albumin Dialysis (SPAD)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Tanvi Parikh ◽  
Meeta Sharma ◽  
Aroti Hegde
Keyword(s):  
Thyroid Storm ◽  
Albumin Dialysis ◽  
Single Pass

Albumin dialysis: single pass vs. recirculation (MARS)

2002 ◽  
Vol 22 ◽  
pp. 40-42 ◽  
Author(s):  
P Peszynski ◽  
S Klammt ◽  
E Peters ◽  
S Mitzner ◽  
J Stange ◽  
...  
Keyword(s):  
Albumin Dialysis ◽  
Single Pass

scholarly journals Single-pass albumin dialysis in a child aged six months with phenobarbital poisoning

2016 ◽  
Vol 51 (4) ◽  
pp. 228-230 ◽  
Author(s):  
Hasan Serdar Kihtir ◽  
Hamdi Murat Yildirim ◽  
Osman Yesilbas ◽  
Burcu Bursal Duramaz ◽  
Esra Sevketoglu
Keyword(s):  
Albumin Dialysis ◽  
Single Pass

Diagnoses in Opposition: Thyroid Storm and Myxedema Coma

1992 ◽  
Vol 3 (2) ◽  
pp. 300-308 ◽  
Author(s):  
Loretta Spittle
Keyword(s):  
Patient Outcomes ◽  
Signs And Symptoms ◽  
Management Team ◽  
Thyroid Storm ◽  
Normal Thyroid ◽  
Myxedema Coma ◽  
Normal Thyroid Function ◽  
Life Threatening ◽  
Nursing Diagnoses

An overview of normal thyroid function is presented to facilitate the understanding of the pathophysiology of two life-threatening thyroid disorders: thyroid storm and myxedema coma. Signs and symptoms, medical management, nursing diagnoses and interventions, and expected patient outcomes are discussed, as is the important role of the nurse as an integral member of the management team

scholarly journals Single Pass Albumin Dialysis and Plasma Exchange for Copper Toxicity in Acute Wilson Disease

2019 ◽  
Vol 9 (2) ◽  
pp. 55-63
Author(s):  
Shireen Bakhsh ◽  
Chia Wei Teoh ◽  
Elizabeth A. Harvey ◽  
Damien G. Noone
Keyword(s):  
Liver Transplantation ◽  
Plasma Exchange ◽  
Hemolytic Anemia ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Wilson Disease ◽  
Serum Copper ◽  
Albumin Dialysis ◽  
Single Pass ◽  
Rebound Increase

Background: Wilson disease (WD) is a disorder of copper metabolism that results in accumulation of copper in tissues. In acute WD, patients present with fulminant hepatic failure, encephalopathy, and hemolytic anemia due to copper release from necrotic hepatocytes. Many will require life-saving liver transplantation. Extracorporeal liver support systems can provide a bridge to transplantation for critically ill patients. We report our experience with 2 patients for whom we used a combination of plasma exchange (PLEX) and single pass albumin dialysis (SPAD), or SPAD alone as a bridge to liver transplantation. Case Reports: A 17-year-old girl (patient 1) and a 12-year-old boy (patient 2) presented with fulminant hepatic failure, hemolytic anemia, and acute kidney injury. Patient 1 received SPAD on days 2 and 3 (total 32 h). Serum copper decreased from 22.3 to 15.9 µmol/L (28.7% decrease), measured after 28 h of continuous SPAD. She underwent successful liver transplantation on day 4 after presentation. Patient 2 was treated with PLEX on days 1, 3, 4, and 5 and with SPAD on days 3–6. Serum copper decreased from 48.7 to 25.8 µmol/L (47% decrease) after the first session of PLEX and from 35.5 to 21.5 µmol/L (39.4% decrease) after the second session. The serum copper level was 16.2 µmol/L after 4 sessions of PLEX (and ongoing SPAD), with an overall 66.7% reduction in copper levels over 5 days combining both therapies. He underwent successful liver transplantation on day 6. Conclusion: We conclude that SPAD, with or without PLEX, is effective in reducing serum copper levels as a bridge to liver transplantation in WD. PLEX may be more efficient at removing copper but is associated with a rebound increase in copper levels between sessions.

scholarly journals Single-Pass Albumin Dialysis in the Treatment of Children with Liver Failure

2019 ◽  
Vol 49 (1-2) ◽  
pp. 55-62
Author(s):  
Johannes Holle ◽  
Alexander Gratopp ◽  
Sophie Balmer ◽  
Verena Varnholt ◽  
Stephan Henning ◽  
...  
Keyword(s):  
Liver Failure ◽  
Pediatric Patients ◽  
Serum Levels ◽  
Albumin Dialysis ◽  
Liver Support ◽  
Single Pass ◽  
Medical Chart Review ◽  
Extracorporeal Liver Support ◽  
Life Threatening ◽  
Catecholamine Therapy

Background and Aims: Acute and acute on chronic liver failure are life-threatening conditions, and bridging to transplantation is complicated by a paucity of suitable organs for children. While different modalities of extracorporeal liver support exist, their use in children is complicated by a large extracorporeal volume, and data on their use in children is limited. The aim of this analysis was to investigate the efficacy and safety of single-pass albumin dialysis (SPAD) in children with liver failure. Methods: Retrospective medical chart review of pediatric patients with liver failure treated with SPAD. The decrease in hepatic encephalopathy (HE) and the serum levels of bilirubin and ammonia were measured to determine efficacy. Adverse events were documented to assess safety. Results: Nineteen pediatric patients with a median age of 25.5 months and a median body weight of 11.9 kg were treated with SPAD between January 2011 and March 2018. Total bilirubin (p < 0.001) and ammonia (p = 0.02) significantly decreased after treatment with SPAD. As clinical outcome parameter, HE significantly improved (p = 0.001). Twelve patients were bridged successfully to liver transplantation. In all patients, 71 SPAD sessions were run. Clotting in the dialysis circuit was observed in 49% of all sessions. Heparin and citrate were used for anticoagulation and were significantly superior to dialysis without any anticoagulation (p= 0.03). Transfusion of packed blood cells (57%) and catecholamine therapy (49%) were frequently necessary. Conclusions: Treatment with SPAD was effective in detoxification, as measured by significant improvement of HE and clearance from surrogate laboratory parameters.

Effective Bilirubin Reduction by Single-Pass Albumin Dialysis in Liver Failure

2009 ◽  
Vol 33 (8) ◽  
pp. 648-653 ◽  
Author(s):  
Ussanee Boonsrirat ◽  
Khajohn Tiranathanagul ◽  
Nattachai Srisawat ◽  
Paweena Susantitaphong ◽  
Piyawat Komolmit ◽  
...  
Keyword(s):  
Liver Failure ◽  
Albumin Dialysis ◽  
Single Pass

scholarly journals Successful Management of Sickle Cell Intrahepatic Cholestasis with Combined Use of Exchange Transfusion and Single-Pass Albumin Dialysis: A Case Report

2013 ◽  
Vol 03 (01) ◽  
pp. 36-42 ◽  
Author(s):  
Vassilios Papadopoulos ◽  
Anna Karagianni ◽  
Vaia Papageorgiou ◽  
Maria Topalidou ◽  
Aristea-Lia Mpellou ◽  
...  
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Intrahepatic Cholestasis ◽  
Exchange Transfusion ◽  
Successful Management ◽  
Albumin Dialysis ◽  
Single Pass ◽  
Combined Use
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