Safety and feasibility of 1 month of daily rifapentine plus isoniazid to prevent tuberculosis in children and adolescents: a prospective cohort study

2021 ◽  
Vol 5 (5) ◽  
pp. 350-356 ◽  
Author(s):  
Amyn A Malik ◽  
Saira Farooq ◽  
Maria Jaswal ◽  
Hiba Khan ◽  
Kumail Nasir ◽  
...  
Keyword(s):  
Cohort Study ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Tuberculosis In Children

scholarly journals Risk Factors for the Occurrence and Protraction of Anterior Knee Pain in Children and Adolescents: a Prospective Cohort Study of 3 Years

2021 ◽  
Author(s):  
Manato Horii ◽  
Ryuichiro Akagi ◽  
Sho Takahashi ◽  
Shotaro Watanabe ◽  
Yuya Ogawa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cohort Study ◽  
Children And Adolescents ◽  
Knee Pain ◽  
Prospective Cohort Study ◽  
Anterior Knee Pain ◽  
Prospective Cohort ◽  
Activity Level ◽  
Anterior Knee

Abstract Background: Anterior knee pain (AKP) is a common limitation to children’s participation in social and physical activities. Therefore, to prevent the occurrence and protraction of AKP, it is crucial to identify risk factors. The purpose of this study was to clarify the factors associated with the occurrence and protraction of AKP in children and adolescents. Method: A three-year prospective cohort study was conducted with children and adolescents aged 8–14 in Japan. We recorded the occurrence of AKP, heel buttock distance, straight leg raising angle (SLRA), dorsiflexion angle of the ankle joint, and the Hospital for Special Surgery Pediatric Functional Activity Brief Scale (HSS Pedi-FABS). Logistic regression analysis was performed to calculate the odds ratio (OR) for each predicted risk factor for the occurrence and protraction of AKP among subjects without AKP at baseline. Results: We recruited 1,254 children and adolescents for the present study, and 1,133 children and adolescents who did not have AKP at baseline were included in the analysis. Six to nine percent of the subjects developed AKP annually. A high HSS Pedi-FABS score significantly predicted AKP occurrence (in 2017, OR 1.07, 95% CI 1.02−1.12, p = 0.003; in 2018, OR 1.05, 95% CI 1.01−1.10, p = 0.025). Of the participants, 32.9% developed chronic AKP during the follow-up period. When 8-year-old was used as a reference age, 13-year-old subjects (right side, OR 2.37, 95% CI, 1.00−5.61, p = 0.05) and 14-year-old subjects (right side, OR 2.57, 95% CI, 1.00−6.60, p = 0.049; left side, OR 6.32; 95% CI 1.33−30.00, p = 0.020) were at a significantly higher risk of AKP protraction. Conclusions: This study showed that a greater physical activity level was a risk factor for the onset of anterior knee pain in childhood. In addition, one-third of the children and adolescents developed chronic knee pain, and elderly adolescents were at a higher risk of protraction.

scholarly journals Nutritional status of children and adolescents with cancer in Scotland: A prospective cohort study

2019 ◽  
Vol 32 ◽  
pp. 96-106 ◽  
Author(s):  
Raquel Revuelta Iniesta ◽  
Ilenia Paciarotti ◽  
Isobel Davidson ◽  
Jane M. McKenzie ◽  
Mark F.H. Brougham ◽  
...  
Keyword(s):  
Cohort Study ◽  
Nutritional Status ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Nutritional Status Of Children

scholarly journals Safety of Intranasal Quadrivalent Live Attenuated Influenza Vaccine (QLAIV) in Children and Adolescents: A Pilot Prospective Cohort Study in England

Drug Safety ◽  
2016 ◽  
Vol 39 (4) ◽  
pp. 323-333 ◽  
Author(s):  
Rhian McNaughton ◽  
Elizabeth Lynn ◽  
Vicki Osborne ◽  
Abigail Coughtrie ◽  
Deborah Layton ◽  
...  
Keyword(s):  
Cohort Study ◽  
Influenza Vaccine ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Live Attenuated Influenza Vaccine

Falls in paediatric Charcot-Marie-Tooth disease: a 6-month prospective cohort study

2018 ◽  
Vol 104 (6) ◽  
pp. 535-540 ◽  
Author(s):  
Rachel A Kennedy ◽  
Kate Carroll ◽  
Graham Hepworth ◽  
Kade L Paterson ◽  
Monique M Ryan ◽  
...  
Keyword(s):  
Cohort Study ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Common Mechanism ◽  
Charcot Marie Tooth ◽  
Paediatric Hospital ◽  
Charcot Marie Tooth Disease ◽  
Injurious Falls ◽  
Tooth Disease

ObjectiveTo prospectively study falls in children and adolescents with Charcot-Marie-Tooth disease (CMT).DesignProspective cohort study.SettingNeuromuscular outpatient clinic of a tertiary paediatric hospital.PatientsSixty children and adolescents (‘children’) aged 4–18 years, 30 with CMT and 30 typically developing (TD).Main outcome measuresFalls rate over 6 months and falls characteristics questionnaire.ResultsTwenty-two children with CMT reported falling at least once in 6 months compared with eight TD children (CMT 2819 (0–1915), TD 31 (0–6) total falls (range)). Detailed falls characteristics were collected from 242 individual falls (CMT 216, TD 26). Injurious falls were reported by 19 children with CMT (74 falls) compared with 2 TD children (3 falls), with cuts, grazes and bruising most common. No fractures were sustained and no child required hospitalisation. However, 12 injuries from falls in children with CMT required management by a healthcare provider, versus none in TD children. Tripping was the most common mechanism of falls in both groups. Age was the strongest predictor of falls (ρ=−0.53, p=0.006) with all children (CMT and TD) aged <7 years falling. Balance was the strongest impairment-related predictor of falls (ρ=−0.47, p=0.02). The conservative estimate of risk of falls in children and adolescents with CMT was 33 times higher than their TD peers (incidence rate ratio=32.8, 95% CI 10.2 to 106.0).ConclusionsChildren and adolescents with CMT fall more often than TD peers and sustain more injuries when they fall.

scholarly journals Adiposity trajectory and its associations with plasma adipokine levels in children and adolescents-A prospective cohort study

Obesity ◽  
2015 ◽  
Vol 24 (2) ◽  
pp. 408-416 ◽  
Author(s):  
Shenghui Li ◽  
Rong Liu ◽  
Lester Arguelles ◽  
Guoying Wang ◽  
Jun Zhang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Prospective Cohort

scholarly journals Validation of Continuous Glucose Monitoring in Children and Adolescents With Cystic Fibrosis: A prospective cohort study

Diabetes Care ◽  
2009 ◽  
Vol 32 (6) ◽  
pp. 1020-1022 ◽  
Author(s):  
S. M.P. O'Riordan ◽  
P. Hindmarsh ◽  
N. R. Hill ◽  
D. R. Matthews ◽  
S. George ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Cohort Study ◽  
Children And Adolescents ◽  
Prospective Cohort Study ◽  
Continuous Glucose Monitoring ◽  
Prospective Cohort ◽  
Glucose Monitoring
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