Psychomotor development and minor anomolies in children exposed to antiepileptic drugs in utero: a population-based study

2000 ◽  
Vol 42 (5) ◽  
pp. 356-356
Author(s):  
Katarina Wide ◽  
Birger Winbladh ◽  
Torbjörn Tomson ◽  
Kerstin Sars-Zimmer ◽  
Eva Berggren
Epilepsia ◽  
2013 ◽  
Vol 54 (8) ◽  
pp. 1462-1472 ◽  
Author(s):  
Gyri Veiby ◽  
Anne K. Daltveit ◽  
Synnve Schjølberg ◽  
Camilla Stoltenberg ◽  
Anne-Siri Øyen ◽  
...  

2015 ◽  
Vol 46 (4) ◽  
pp. 855-863 ◽  
Author(s):  
S. Z. Levine ◽  
I. Levav ◽  
Y. Goldberg ◽  
I. Pugachova ◽  
Y. Becher ◽  
...  

BackgroundNo evidence exists on the association between genocide and the incidence of schizophrenia. This study aims to identify critical periods of exposure to genocide on the risk of schizophrenia.MethodThis population-based study comprised of all subjects born in European nations where the Holocaust occurred from 1928 to 1945, who immigrated to Israel by 1965 and were indexed in the Population Register (N = 113 932). Subjects were followed for schizophrenia disorder in the National Psychiatric Case Registry from 1950 to 2014. The population was disaggregated to compare groups that immigrated before (indirect exposure: n = 8886, 7.8%) or after (direct exposure: n = 105 046, 92.2%) the Nazi or fascist era of persecutions began. The latter group was further disaggregated to examine likely initial prenatal or postnatal genocide exposures. Cox regression modelling was computed to compare the risk of schizophrenia between the groups, adjusting for confounders.ResultsThe likely direct group was at a statistically (p < 0.05) greater risk of schizophrenia (hazard ratio = 1.27, 95% confidence interval 1.06–1.51) than the indirect group. Also, the likely combined in utero and postnatal, and late postnatal (over age 2 years) exposure subgroups were statistically at greater risk of schizophrenia than the indirect group (p < 0.05). The likely in utero only and early postnatal (up to age 2 years) exposure subgroups compared with the indirect exposure group did not significantly differ. These results were replicated across three sensitivity analyses.ConclusionsThis study showed that genocide exposure elevated the risk of schizophrenia, and identified in utero and postnatal (combined) and late postnatal (age over 2 years) exposures as critical periods of risk.


2015 ◽  
Vol 70 (8) ◽  
pp. 830-834 ◽  
Author(s):  
A.C. Nordenskjöld ◽  
M. Palme ◽  
M. Kaijser

Epilepsia ◽  
2014 ◽  
Vol 55 (11) ◽  
pp. 1714-1721 ◽  
Author(s):  
Demet Kilic ◽  
Henrik Pedersen ◽  
Maiken Ina Siegismund Kjaersgaard ◽  
Erik Thorlund Parner ◽  
Mogens Vestergaard ◽  
...  

2014 ◽  
Vol 16 (3) ◽  
pp. 333-342 ◽  
Author(s):  
Fang-Jen Wu ◽  
Shiow-Yunn Sheu ◽  
Herng-Ching Lin

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