<p>&#160; &#160; The Moon is sometimes also called the "eighth continent" of the Earth. Determining how to utilize cis-lunar orbital infrastructures and lunar resources to carry out new economic activities extended to the space of the Earth-Moon system is one of the long-term goals of lunar exploration activities around the world. Future long-term human deep-space exploration missions to the Moon, on the Moon surface or using the Moon to serve farther destinations will require the utilization of lunar surface or asteroid resources to produce water, oxygen and other consumables needed to maintain human survival and to produce liquid propellant for the supply of spacecraft on the lunar surface. In complement to exploration activities, Moon tourism in cis-lunar orbit and on the lunar surface will become more and more attractive with the increase of &#160;human spaceflight capacity and the development of commercial space activities. However, the development of a sustainable Earth-Moon ecosystem requires that we solve the following five problems:</p><p>(1)How to design alow-cost cis-lunar space transportation capacity?&#160;To find an optimal solution, one must compare&#160;direct Earth-Moon flight modes with flights&#160;based on&#160;the utilization of&#160;space stations, and identify the&#160;most economical spacecraft architectures.</p><p>(2)How to design an efficient set ofcis-lunar&#160;orbital&#160;infrastructures combining LEO space stations, Earth-Moon L1/L2 point space stations and&#160;Moon&#160;bases&#160;for commercial tourism, taking into account key issues such as energy,&#160;communications and others?</p><p>(3)Significant amounts ofliquid oxygen, water,&#160;liquid propellant&#160;and structural material will be needed&#160;for human bases, crew environmental control and life support systems, spacecraft propulsion systems, Moon surface storage and transportation&#160;systems. How to &#160;design in-situ resources utilization (ISRU) of the Moon, including its soil, rocks and polar&#160;water ice reservoirs, to produce&#160;the needed amounts?</p><p>(4) How to simulate on the Earth surface the different components and key technologies that will enable a future long-term human residence on the Moon surface?</p><p>(5). How to accommodate the co-development of&#160;public and commercial&#160;space&#160;and foster international cooperation?&#160;How can space policies and international space law help this co-development?</p><p>&#160; &#160; China has made rapid progress in robotic lunar exploration activities in the last 20 years, as illustrated by the recent discoveries provided by the Chang'e-4 lander on the far side of the Moon. By 2061, China will have gone into manned lunar exploration and built Moon bases. In preparation for this new phase of its contribution to space exploration, lunar surface simulation instruments have been built in Beijing, Shenzhen and other places in China. A series of achievements have been made in the field of space life sciences . An ambitious project to establish a large Moon base simulation test field, the Lunar Base Yulin (LBY) project, currently in its design phase in Yulin, Shaanxi Province in China, will allow the verification of key relevant technologies.</p><p>&#160; &#160; By the 2061 Horizon, we believe that international cooperation and public-private partnership will be key elements to enable this vision of a new, sustainable cis-lunar space economy.</p>