Personality, bioelectric profile and platelet monoamine oxidase activity in psychophysiological disorders: headaches, insomnia and loss of consciousness due to neurocirculatory dystonia

1988 ◽  
Vol 3 (4) ◽  
pp. 263-267
Author(s):  
J.M. Arqué Bertran ◽  
R. Torrubia Beltri
Keyword(s):  
Monoamine Oxidase ◽  
Sensation Seeking ◽  
Minnesota Multiphasic Personality Inventory ◽  
Control Group ◽  
Loss Of Consciousness ◽  
Mao B ◽  
Platelet Monoamine Oxidase ◽  
Psychophysiological Disorders ◽  
Sensation Seeking Scale ◽  
Patient Subgroups

SummaryA comparative study was carried out between a control group and different patient subgroups suffering from psychosonratic disorders: headache, insomnia and loss of consciousness due to neurocirculatory dystonia.Different personality questionnaires (Minnesota Multiphasic Personality Inventory, Sensation Seeking Scale, Susceptibility to Punishment Scale), neurobioelectric parameters (Hjörth descriptors, alpha percentage, P100, N120 P200 of visual evoked responses) and platelet monoamine oxidase B (using phenylethylamine as substrate) were evaluated.The results show a significant increase in anxiety indicators (at a psychometric and bioelectric level) in the headache and insomnia groups. MAO B activity was higher in patients, especially in the insomniac group; but no significant differences were found in any of the groups studied.

Low Platelet Monoamine Oxidase Activity in Sensation-Seeking Bullfighters

CNS Spectrums ◽  
1999 ◽  
Vol 4 (12) ◽  
pp. 21-24 ◽  
Author(s):  
José Luis Carrasco ◽  
Jerónimo Sáiz-Ruiz ◽  
Marina Díaz-Marsá ◽  
Jesús César ◽  
Juan José López-Ibor
Keyword(s):  
Monoamine Oxidase ◽  
Sensation Seeking ◽  
Behavioral Pattern ◽  
Control Group ◽  
Platelet Mao ◽  
Isotopic Methods ◽  
Healthy Control ◽  
Mao Activity ◽  
Platelet Mao Activity ◽  
Platelet Monoamine Oxidase

AbstractIn this study, we attempt to demonstrate an association between low platelet monoamine oxidase (MAO) activity, as assessed by isotopic methods, and the stable behavioral pattern of sensation- and risk-seeking of professional bull-fighters. Sixteen professional bullfighters were studied and compared with a control group of 46 healthy control subjects who did not engage in risky jobs or activities. The group of bullfighters had significantly reduced platelet MAO activity compared with the control group (P<0.05). Bullfighters were shown to be significantly more extroverted and sensation-seeking than controls on various temperament scales. A predisposition to engage in risky activities (eg, bullfighting) and sensation-seeking could be partly conditioned by the presence of biological components of personality manifested by a significantly decreased platelet MAO activity.

scholarly journals Platelet Monoamine Oxidase B Activity in “de novo” and L-Dopa Treated Parkinsonian Patients and Controls

1998 ◽  
Vol 25 (3) ◽  
pp. 249-251 ◽  
Author(s):  
Wilfried Kuhn ◽  
Thomas Müller ◽  
Anja Gerstner ◽  
Regina Winkel ◽  
Mario E. Goetz
Keyword(s):  
Monoamine Oxidase ◽  
De Novo ◽  
Enzymatic Assay ◽  
Monoamine Oxidase B ◽  
Mao B ◽  
Levodopa Treatment ◽  
Platelet Mao ◽  
Platelet Monoamine Oxidase ◽  
Age And Sex

ABSTRACT:Objective:Previous studies demonstrated controversial results regarding monoamine oxidase B (MAO-B) activity in platelets in the periphery in parkinsonian patients (PD).Subjects and Methods:Therefore we determined platelet MAO-B activity in three age- and sex-matched groups of 17 untreated, so called “de novo” patients with Parkinson's disease (PD), 17 parkinsonian patients, receiving levodopa, and 17 controls by a radio enzymatic assay.Results:No significant differences of MAO-B activity appeared.Conclusion:This result suggests that phenotypic determination of MAO-B activity in platelets may not be used as peripheral marker in PD and that levodopa treatment does not alter MAO-B activity in the periphery.

Kinetics and Thermolability of Platelet Monoamine Oxidase in Cluster Headache and Migraine

Cephalalgia ◽  
1984 ◽  
Vol 4 (2) ◽  
pp. 125-134 ◽  
Author(s):  
Elisabet Waldenlind ◽  
Jan Sääf ◽  
Karl Ekbom ◽  
Svante Ross ◽  
Lars-Olof Wahlund ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Cluster Headache ◽  
Control Group ◽  
Enzyme Properties ◽  
Headache Disorders ◽  
Platelet Mao ◽  
Mao Activity ◽  
Platelet Mao Activity ◽  
Platelet Monoamine Oxidase ◽  
C 30

Platelet monoamine oxidase activity (MAO) from 33 cluster headache patients (17 males, 16 females) and 34 migraine patients (16 males, 18 females) was assayed. The kinetic constants (apparent V max and apparent K m ) and the thermolability, measured as the ratio of the platelet MAO activity after and before heat treatment (+52°C, 30 min), were determined. The MAO activity and V max values were significantly lower in cluster headache than in migraine and in both headache disorders compared to a control group (62 males, 66 females). When comparing all groups, K m was not significantly different except for migraine females, who had lower K m values compared to control females. Thermolability was significantly higher in cluster headache than in migraine and in both headache disorders compared to the control group. Smokers of five cigarettes or more per day had significantly lower Vmax values but similar K m and thermolability values compared to those smoking less or nothing. The findings of low maximal velocities and high thermolability of platelet MAO in cluster headache and migraine are suggested to represent constitutionally different enzyme properties.

Sensation Seeking in a French Population of Pathological Gamblers: Comparison with Regular and Nongamblers

2004 ◽  
Vol 94 (3_suppl) ◽  
pp. 1361-1371 ◽  
Author(s):  
Céline Bonnaire ◽  
Michel Lejoyeux ◽  
Roland Dardennes
Keyword(s):  
General Population ◽  
Sensation Seeking ◽  
Control Group ◽  
French Population ◽  
Multiple Forms ◽  
Pathological Gamblers ◽  
Sensation Seeking Scale

To test the hypothesis that pathological gamblers in the French general population who play games available in cafés score lower on sensation seeking than regular and nongamblers, the Zuckerman's Sensation Seeking Scale was administered to 57 diagnosed pathological gamblers, 40 regular gamblers, and a control group of 97 nongamblers. Whereas pathological gamblers did not obtain a significantly lower Sensation Seeking mean than the regular and nongamblers groups, analysis indicated that those pathological gamblers seek different and multiple forms of games to reduce boredom, but they do not necessarily seek excitement-generating activities. One possible interpretation is that the types of games investigated in this study are “passive” forms of games that required low involvement from the gamblers.

Low platelet monoamine oxidase and sensation seeking in males: an established relationship?

1987 ◽  
Vol 75 (1) ◽  
pp. 86-90 ◽  
Author(s):  
P. B. Ward ◽  
S. V. Catts ◽  
T. R. Norman ◽  
G. D. Burrows ◽  
N. McConaghy
Keyword(s):  
Monoamine Oxidase ◽  
Sensation Seeking ◽  
Established Relationship ◽  
Platelet Monoamine Oxidase

scholarly journals Detention in Juvenile Correctional Facilities Is Associated with Higher Platelet Monoamine Oxidase B Activity in Males

Biomolecules ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1555
Author(s):  
Josip Podobnik ◽  
Matea Nikolac Perkovic ◽  
Gordana Nedic Erjavec ◽  
Katarina Dodig Curkovic ◽  
Mario Curkovic ◽  
...  
Keyword(s):  
Juvenile Delinquency ◽  
Monoamine Oxidase ◽  
Correctional Facility ◽  
Delinquent Behavior ◽  
Monoamine Oxidase B ◽  
Male Adolescents ◽  
Mao B ◽  
Platelet Mao ◽  
Platelet Monoamine Oxidase ◽  
Enzyme Monoamine Oxidase

Juvenile delinquency is related to several biological factors, yet very few vulnerability biomarkers have been identified. Previous data suggest that the enzyme monoamine oxidase B (MAO-B) influences several personality traits linked to the propensity to engage in delinquent behavior. Building on this evidence, we assessed whether conduct disorder (CD), juvenile delinquency adjudications, or detention in a correctional facility were associated with either platelet MAO-B activity or the MAOB rs1799836 polymorphism. The study enrolled 289 medication-free male youths, including 182 individuals detained in a correctional facility (with or without a diagnosis of CD). Of the remaining 107 participants, 26 subjects had a diagnosis of CD, and 81 were mentally healthy controls. Platelet MAO-B activity was determined by spectrophotofluorometry, while MAOB rs1799836 was genotyped using qPCR. Platelet MAO-B activity, corrected for age and smoking, was significantly higher in juvenile detainees (p < 0.001), irrespective of CD diagnosis. MAOB rs1799836 was not associated with platelet MAO-B activity or with detention in a correctional facility, CD diagnosis, or delinquent behavior. These data suggest that detention in a juvenile correctional facility increases platelet MAO-B activity in male adolescents. Future studies are needed to determine the mechanisms and functional significance of MAO-B peripheral elevation in juvenile male detainees.

scholarly journals Application of Assay of Platelet Monoamine Oxidase Type-B (MAO-B) Activity to the Discrimination of Selegiline Use from Methamphetamine Abuse

2003 ◽  
Vol 49 (3) ◽  
pp. 189-194 ◽  
Author(s):  
Munehiro Katagi ◽  
Hiroe Tsutsumi ◽  
Michiaki Tatsuno ◽  
Tohru Kamata ◽  
Hiroshi Nishioka ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Type B ◽  
Methamphetamine Abuse ◽  
Mao B ◽  
Platelet Monoamine Oxidase ◽  
Monoamine Oxidase Type B

Relationship between platelet monoamine oxidase-B (MAO-B) activity and mercury exposure in fish consumers from the Lake St. Pierre region of Que., Canada

2006 ◽  
Vol 27 (3) ◽  
pp. 429-436 ◽  
Author(s):  
Christopher John Stamler ◽  
Nadia Abdelouahab ◽  
Claire Vanier ◽  
Donna Mergler ◽  
Hing Man Chan
Keyword(s):  
Monoamine Oxidase ◽  
Mercury Exposure ◽  
Monoamine Oxidase B ◽  
Mao B ◽  
Platelet Monoamine Oxidase

Construct Validity of Sensation Seeking: A Psychometric Investigation

1999 ◽  
Vol 20 (3) ◽  
pp. 155-171 ◽  
Author(s):  
André Beauducel ◽  
Burkhard Brocke ◽  
Alexander Strobel ◽  
Anja Strobel
Keyword(s):  
Substance Use ◽  
Construct Validity ◽  
Psychometric Properties ◽  
Factor Structure ◽  
Sensation Seeking ◽  
German Version ◽  
Trait Theory ◽  
Multilevel Theory ◽  
Sensation Seeking Scale ◽  
Psychometric Investigation

Abstract: Zuckerman postulated a biopsychological multilevel theory of Sensation Seeking, which is part of a more complex multi-trait theory, the Alternative Five. The Sensation Seeking Scale Form V (SSS V) was developed for the measurement of Sensation Seeking. The process of validation of Sensation Seeking as part of a multilevel theory includes analyses of relations within and between several levels of measurement. The present study investigates validity and basic psychometric properties of a German version of the SSS V in a broader context of psychometric traits. - The 120 participants were mainly students. They completed the SSS V, the Venturesomeness- and Impulsiveness-Scales of the IVE, the BIS/BAS-Scales, the ZKPQ and the NEO-FFI. - The results reveal acceptable psychometric properties for the SSS V but with limitations with regard to factor structure. Indications for criterion validity were obtained by prediction of substance use by the subscales Dis and BS. The results of a MTMM analysis, especially the convergent validities of the SSS V were quite satisfying. On the whole, the results yielded sufficient support for the validity of the Sensation Seeking construct or the instrument respectively. They also point to desirable modifications.

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