Twin Models
1970 ◽
Vol 19
(1-2)
◽
pp. 141-141
Keyword(s):
The theoretical relationship between the distribution of a given trait in a population of twin pairs and several genetic parameters has been examined. In particular, a series of mathematical models has been worked out, that, when applied to a twin population, nonselected for the occurrence of a given trait and nondiagnosed as to zygosity, leads to an estimate of:1) The MZ: DZ ratio in the population;2) The frequency of the genotype responsible for a given trait;3) The probability of manifestation of the trait;4) The value of epistatic factors.A further mathematical model affords the estimate of linkage in the hypothesis of simultaneous recording of more than one trait.