Pre-pregnancy maternal overweight and obesity increase the risk for affective disorders in offspring

2012 ◽  
Vol 4 (1) ◽  
pp. 42-48 ◽  
Author(s):  
M. Robinson ◽  
S. R. Zubrick ◽  
C. E. Pennell ◽  
R. J. Van Lieshout ◽  
P. Jacoby ◽  
...  
Keyword(s):  
Child Behavior Checklist ◽  
Overweight And Obesity ◽  
Dysthymic Disorder ◽  
Childhood And Adolescence ◽  
Longitudinal Models ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Increased Risk ◽  
Pregnancy Weight ◽  
Maternal Overweight

Maternal pre-pregnancy obesity has been linked with an increased risk for negative emotionality and inattentiveness in offspring in early childhood. The aim of this study was to examine the association between maternal pre-pregnancy body mass index (BMI) and the development of affective problems (dysthymic disorder, major depressive disorder) throughout childhood and adolescence. In the Western Australian Pregnancy Cohort (Raine) Study, 2900 women provided data on their pre-pregnancy weight, and height measurements were taken at 18 weeks of gestation. BMI was calculated and categorized using standardized methods. Live-born children (n= 2868) were followed up at ages 5, 8, 10, 14 and 17 years using the Diagnostic and Statistical Manual of Mental Disorders-oriented scales of the Child Behavior Checklist (CBCL/4–18). Longitudinal models were applied to assess the relationships between maternal pre-pregnancy BMI and affective problems from age 5 through 17. There was a higher risk of affective problems between the ages of 5 and 17 years among children of women who were overweight and obese compared with the offspring of women in the healthy pre-pregnancy weight range (BMI 18.5–24.99) after adjustment for confounders, including paternal BMI. Maternal pre-pregnancy overweight and obesity may be implicated in the development of affective problems, including depression, in their offspring later in life.

scholarly journals Incidence of Delirium in Hospitalized Children with Cancer

2019 ◽  
Vol 4 (2) ◽  
Keyword(s):  
Cognitive Deficits ◽  
Pediatric Intensive Care ◽  
Limited Data ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm V ◽  
Increased Risk ◽  
Short Period ◽  
Fluctuating Course

Delirium is defined in the Diagnostic and Statistical Manual of Mental Disorders: Fifth edition (DSM-V) as a “disturbance and change in attention and awareness from baseline that develops over a short period of time, with fluctuating course” [1]. Delirium occurs as a result of factors related to primary illness, the treatment of that illness, and stressful and disorientating environment of the hospital [2]. There are limited data to describe the incidence of delirium in children hospitalized with cancer [3]. Delirium occurs frequently in adults and is an independent predictor of mortality, increased length of stay, and increased risk for long-term cognitive deficits [3]. The prevalence of delirium in hospitalized adults ages 18-56 with cancer ranges from 18%-44% [4]. Most pediatric studies on delirium focus on the critically ill child in the pediatric intensive care unit (PICU). It is estimated that the incidence of delirium in this population is as high as 29% [5].

Externalizing and internalizing symptoms in childhood and adolescence and the risk of alcohol use disorders in young adulthood: A meta-analysis of longitudinal studies

2019 ◽  
Vol 53 (10) ◽  
pp. 965-975 ◽  
Author(s):  
Ivete Meque ◽  
Berihun Assefa Dachew ◽  
Joemer C Maravilla ◽  
Caroline Salom ◽  
Rosa Alati
Keyword(s):  
Alcohol Use ◽  
Young Adulthood ◽  
Odds Ratio ◽  
Internalizing Symptoms ◽  
Meta Analysis ◽  
Alcohol Use Disorders ◽  
Childhood And Adolescence ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Externalizing And Internalizing Symptoms

Background: Evidence suggests that externalizing and internalizing symptoms are expressed early in life and are associated with problematic drinking in young adulthood. However, few studies have examined their role during childhood and adolescence in predicting alcohol problems later in life. Objectives: To examine the role of childhood and adolescent externalizing and internalizing symptoms in predicting alcohol use disorders in young adulthood. Methods: We searched five electronic databases (PubMed, Scopus, PsycINFO, Web of Sciences and Embase) for studies which diagnosed alcohol use disorders through either the International Classification of Diseases or American Psychiatric Association – Diagnostic and Statistical Manual of Mental Disorders criteria and followed up children or adolescents into the transition to young adulthood. We performed a meta-analysis and obtained pooled odds ratio estimates with 95% confidence intervals using random-effects models. Results: A total of 12 longitudinal studies met eligibility criteria and were included in the meta-analysis. All measured the outcome using Diagnostic and Statistical Manual of Mental Disorders criteria. The majority were of good quality and were conducted in the United States. A total of 19,407 participants (50% female) were included in this meta-analysis. Of these, n = 2337 (12%) had diagnoses of alcohol use disorders/alcohol dependence. Participant ages ranged from birth to 36 years. Internalizing symptoms increased the risk of young adult alcohol use disorders by 21% (odds ratio = 1.21; 95% confidence interval = [1.05, 1.39]), with no strong evidence of publication bias. Subgroup analysis suggested significantly lower heterogeneity than for externalizing studies. Externalizing symptoms increased the risk of alcohol use disorders by 62% (odds ratio = 1.62, 95% confidence interval = [1.39, 1.90]). We found some evidence of publication bias and significant heterogeneity in the studies. Conclusion: Our findings highlight the contribution of early behavioural problems to the development of alcohol use disorders in young adulthood and the need for timely scrutiny of and intervention on early behavioural problems.

Long-term outcome and psychiatric comorbidity of adolescent-onset anorexia nervosa

2019 ◽  
Vol 25 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Susana Andrés-Pepiñá ◽  
Maria Teresa Plana ◽  
Itziar Flamarique ◽  
Sonia Romero ◽  
Roger Borràs ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Control Group ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Increased Risk ◽  
A Current

Objective: To assess the outcome of adolescents with anorexia nervosa (AN) about 20 years after first treatment. Methods: Sixty-two women diagnosed with AN during adolescence were invited to participate. Of these 62 patients, 38 agreed to participate and were assessed with a battery of questionnaires and interviews. A control group of 30 women of similar age was also assessed. Results: Of the patients who completed the full assessment, 13 (34%) presented some degree of eating disorder (ED) at follow-up (10 (26%) met full Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for an ED and 3 (8%) showed partial remission of an ED). The remaining 25 (66%) patients had fully recovered from AN. The duration of untreated illness before admission was significantly associated with an increased risk of a current ED (odds ratio (OR) = 3.334 (1.3–8.7); p = .014). Of the patients who had recovered totally from their ED, 24% showed another psychiatric disorder. This percentage rose to 70% in patients with a current ED. Conclusion: Sixty-six percent of adolescents who completed the assessment achieved remission of their AN. Comorbidity was more common in the current ED group. The variable that best predicted complete remission was the number of years without treatment, showing the importance of detection and early intervention.

scholarly journals Is maternal weight gain between pregnancies associated with risk of large-for-gestational age birth? Analysis of a UK population-based cohort

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e026220 ◽  
Author(s):  
Nida Ziauddeen ◽  
Sam Wilding ◽  
Paul J Roderick ◽  
Nicholas S Macklon ◽  
Nisreen A Alwan
Keyword(s):  
Weight Gain ◽  
Gestational Age ◽  
Population Based ◽  
Overweight And Obesity ◽  
Large For Gestational Age ◽  
Adjusted Relative Risk ◽  
Maternal Weight ◽  
Overweight Women ◽  
Increased Risk ◽  
Maternal Overweight

ObjectiveMaternal overweight and obesity during pregnancy increases the risk of large-for-gestational age (LGA) birth and childhood obesity. We aimed to investigate the association between maternal weight change between subsequent pregnancies and risk of having a LGA birth.DesignPopulation-based cohort.SettingRoutinely collected antenatal healthcare data between January 2003 and September 2017 at University Hospital Southampton, England.ParticipantsHealth records of women with their first two consecutive singleton live-birth pregnancies were analysed (n=15 940).Primary outcome measureRisk of LGA, recurrent LGA and new LGA births in the second pregnancy.ResultsOf the 15 940 women, 16.0% lost and 47.7% gained weight (≥1 kg/m2) between pregnancies. A lower proportion of babies born to women who lost ≥1 kg/m2(12.4%) and remained weight stable between −1 and 1 kg/m2(11.9%) between pregnancies were LGA compared with 13.5% and 15.9% in women who gained 1–3 and ≥3 kg/m2, respectively. The highest proportion was in obese women who gained ≥3 kg/m2(21.2%). Overweight women had a reduced risk of recurrent LGA in the second pregnancy if they lost ≥1 kg/m2(adjusted relative risk (aRR) 0.69, 95% CI 0.48 to 0.97) whereas overweight women who gained ≥3 kg/m2were at increased risk of new LGA after having a non-LGA birth in their first pregnancy (aRR 1.35, 95% CI 1.05 to 1.75). Normal-weight women who gained weight were also at increased risk of new LGA in the second pregnancy (aRR 1.26, 95% CI 1.06 to 1.50 with gain of 1–3 kg/m2and aRR 1.34, 95% CI 1.09 to 1.65 with gain of ≥3 kg/m2).ConclusionsLosing weight after an LGA birth was associated with a reduced LGA risk in the next pregnancy in overweight women, while interpregnancy weight gain was associated with an increased new LGA risk. Preventing weight gain between pregnancies is an important measure to achieve better maternal and offspring outcomes.

Structure, longitudinal invariance, and stability of the Child Behavior Checklist 1½–5’s Diagnostic and Statistical Manual of Mental Disorders–Autism Spectrum Disorder scale: Findings from Generation R (Rotterdam)

Autism ◽  
2017 ◽  
Vol 23 (1) ◽  
pp. 223-235 ◽  
Author(s):  
Leslie A Rescorla ◽  
Akhgar Ghassabian ◽  
Masha Y Ivanova ◽  
Vincent WV Jaddoe ◽  
Frank C Verhulst ◽  
...  
Keyword(s):  
Autism Spectrum Disorder ◽  
Mental Disorders ◽  
Child Behavior ◽  
Child Behavior Checklist ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Base Rates ◽  
Over Time

Although the Child Behavior Checklist 1½–5’s 12-item Diagnostic and Statistical Manual of Mental Disorders-Autism Spectrum Problems Scale (formerly called Pervasive Developmental Problems scale) has been used in several studies as an autism spectrum disorder screener, the base rate and stability of its items and its measurement model have not been previously studied. We therefore examined the structure, longitudinal invariance, and stability of the Child Behavior Checklist 1½–5’s Diagnostic and Statistical Manual of Mental Disorders-Autism Spectrum Problems Scale in the diverse Generation R (Rotterdam) sample based on mothers’ ratings at 18 months ( n = 4695), 3 years ( n = 4571), and 5 years ( n = 5752). Five items that seemed especially characteristic of autism spectrum disorder had low base rates at all three ages. The rank order of base rates for the 12 items was highly correlated over time ( Qs ⩾ 0.86), but the longitudinal stability of individual items was modest (phi coefficients = 0.15–0.34). Confirmatory factor analyses indicated that the autism spectrum disorder scale model manifested configural, metric, and scalar longitudinal invariance over the time period from 18 months to 5 years, with large factor loadings. Correlations over time for observed autism spectrum disorder scale scores (0.25–0.50) were generally lower than the correlations across time of the latent factors (0.45–0.68). Results indicated significant associations of the autism spectrum disorder scale with later autism spectrum disorder diagnoses.

scholarly journals Association of pre-pregnancy body mass index with adverse pregnancy outcome among first-time mothers

PeerJ ◽  
2020 ◽  
Vol 8 ◽  
pp. e10123
Author(s):  
Li Li ◽  
Yanhong Chen ◽  
Zhifeng Lin ◽  
Weiyan Lin ◽  
Yangqi Liu ◽  
...  
Keyword(s):  
Gestational Age ◽  
Caesarean Delivery ◽  
Gestational Hypertension ◽  
Chinese Women ◽  
Adverse Pregnancy Outcome ◽  
Overweight And Obesity ◽  
Southern Chinese ◽  
Increased Risk ◽  
Adverse Pregnancy ◽  
Maternal Overweight

Background Studies have reported an increased risk of adverse pregnancy outcome associated with pre-pregnancy body mass index (BMI). However, the data on such associations in urban areas of southern Chinese women is limited, which drive us to clarify the associations of pre-pregnancy BMI and the risks of adverse pregnancy outcomes (preterm birth (PTB) and low birth weight (LBW)) and maternal health outcomes (gestational hypertension and cesarean delivery). Methods We performed a hospital-based case-control study including 3,864 Southern Chinese women who gave first birth to a live singleton infant from January 2015 to December 2015. PTB was stratified into three subgroups according to gestational age (extremely PTB, very PTB and moderate PTB). Besides, we combined birth weight and gestational age to dichotomise as being small for gestational age (SGA, less than the tenth percentile of weight for gestation) and non-small for gestational age (NSGA, large than the tenth percentile of weight for gestation), gestational week was also classified into categories of term, 34-36 week and below 34 week.. We then divided newborns into six groups: (1) term and NSGA; (2) 34–36 week gestation and NSGA; (3) below 34 week gestation and NSGA; (4) term and SAG; (5) 34–36 week gestation and SAG; (6) below 34 week gestation and SAG. Adjusted logistic regression models was used to estimate the odds ratios of adverse outcomes. Results Underweight women were more likely to give LBW (AOR = 1.44, 95% CI [1.11–1.89]), the similar result was seen in term and SAG as compared with term and NSAG (AOR = 1.78, 95% CI [1.45–2.17]), whereas underweight was significantly associated with a lower risk of gestational hypertension (AOR = 0.45, 95% CI [0.25–0.82) and caesarean delivery (AOR = 0.74, 95% CI [0.62–0.90]). The risk of extremely PTB is relatively higher among overweight and obese mothers in a subgroup analysis of PTB (AOR = 8.12, 95% CI [1.11–59.44]; AOR = 15.06, 95% CI [1.32–172.13], respectively). Both maternal overweight and obesity were associated with a greater risk of gestational hypertension (AOR = 1.71, 95% CI [1.06–2.77]; AOR = 5.54, 95% CI [3.02–10.17], respectively) and caesarean delivery (AOR = 1.91, 95% CI [1.53–2.38]; AOR = 1.85, 95% CI [1.21–2.82], respectively). Conclusions Our study suggested that maternal overweight and obesity were associated with a significantly higher risk of gestational hypertension, caesarean delivery and extremely PTB. Underweight was correlated with an increased risk of LBW and conferred a protective effect regarding the risk for gestational hypertension and caesarean delivery for the first-time mothers among Southern Chinese.

scholarly journals Perilaku Abnormal Tokoh dalam Antologi Cerpen Bingung Karya Mahasiswa Psikologi UIN Maulana Malik Ibrahim Malang

2021 ◽  
Vol 1 (5) ◽  
pp. 673-682
Author(s):  
Rofiad Darojad Diyaningsih ◽  
Yuni Pratiwi
Keyword(s):  
Short Stories ◽  
Mental Disorders ◽  
Anxiety Disorders ◽  
American Psychiatric Association ◽  
Dissociative Disorders ◽  
Abnormal Behavior ◽  
Childhood And Adolescence ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Dsm Iv

Abstract: This study aims to describe the forms of abnormal behavior, causes, and treatment of abnormal behavior in the anthology of Bingung short stories. This is qualitative research using a literary psychology approach with the object of the study being the anthology of Bingung short stories written by the student of UIN Maulana Malik Ibrahim Malang. There are 22 short stories in the anthology, 17 of which meet the criteria. The criteria for analysis are stories presenting a character with abnormal behavior. The behaviors being observed are those in accordance with the DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) classification published by the APA (American Psychiatric Association). The results of this study indicate, first, that there are four types of abnormal behavior in the anthology, namely (1) anxiety disorders, (2) schizophrenia disorders, (3) dissociative disorders, and (4) abnormal behavior in childhood and adolescence. Second, the causes and treatment of abnormal behavior include (1) causes and treatment of anxiety disorders, (2) causes and treatment of schizophrenia, (3) causes and treatment of abnormal behavior in childhood and adolescence. Keywords: abnormal behavior; characters; the anthology of Bingung short stories Abstrak: Penelitian ini bertujuan untuk mendeskripsikan bentuk-bentuk perilaku abnormal, penyebab, dan penanganan perilaku abnormal dalam antologi cerpen Bingung. Penelitian ini menggunakan jenis penelitian kualitatif, sedangkan pendekatan yang digunakan adalah pendekatan psikologi sastra dengan objek kajian antologi cerpen Bingung karya mahasiswa UIN Maulana Malik Ibrahim Malang. Terdapat 22 cerpen dalam antologi cerpen Bingung, 17 diantaranya merupakan cerpen yang memenuhi kriteria untuk diteliti. Kriteria cerpen yang diteliti adalah cerpen yang di dalamnya menceritakan seorang tokoh berperilaku abnormal dengan bentuk-bentuk perilaku abnormal yang sesuai dengan pedoman penggolongan perilaku abnormal DSM-IV (Diagnostic and Statistical Manual of Mental Disorders) yang diterbitkan oleh APA (American Psychiatric Association). Hasil penelitian ini menunjukkan, pertama, adanya empat tipe perilaku abnormal dalam antologi cerpen Bingung, yaitu (1) gangguan kecemasan, (2) gangguan skizofrenia, (3) gangguan disosiatif, (4) perilaku abnormal pada masa kanak-kanak dan remaja. Kedua, Penyebab dan penanganan perilaku abnormal meliputi (1) penyebab dan penanganan gangguan kecemasan, (2) penyebab dan penanganan pada gangguan skizofrenia, (3) penyebab dan penanganan pada perilaku abnormal pada masa kanak-kanak dan remaja. Kata kunci: perilaku abnormal; tokoh; antologi cerpen bingung

Review of the importance of nutrition during the first 1000 days: maternal nutritional status and its associations with fetal growth and birth, neonatal and infant outcomes among African women

2015 ◽  
Vol 7 (2) ◽  
pp. 144-162 ◽  
Author(s):  
S. V. Wrottesley ◽  
C. Lamper ◽  
P. T. Pisa
Keyword(s):  
Birth Weight ◽  
Nutritional Status ◽  
Fetal Growth ◽  
Overweight And Obesity ◽  
Cochrane Library ◽  
Maternal Body Mass Index ◽  
Infant Outcomes ◽  
Maternal Nutritional Status ◽  
Increased Risk ◽  
Maternal Overweight

Maternal nutritional status (MNS) is a strong predictor of growth and development in the first 1000 days of life and may influence susceptibility to non-communicable diseases in adulthood. However, the role of nutrition during this window of developmental plasticity in Africa is unclear. This paper reviews published data to address whether maternal nutrition during the first 1000 days is important for Africa, with a focus on MNS and its associations with fetal growth and birth, neonatal and infant outcomes. A systematic approach was used to search the following databases: Medline, EMBASE, Web of Science, Google Scholar, ScienceDirect, SciSearch and Cochrane Library. In all, 26 studies met the inclusion criteria for the specific objectives. MNS in Africa showed features typical of the epidemiological transition: higher prevalences of maternal overweight and obesity and lower underweight, poor diet quality 1 and high anaemia prevalence. Maternal body mass index and greater gestational weight gain (GWG) were positively associated with birth weight; however, maternal overweight and obesity were associated with increased risk of macrosomia and intrauterine growth restriction. Maternal anaemia was associated with lower birth weight. Macro- and micronutrient supplementation during pregnancy were associated with improvements in GWG, birth weight and mortality risk. Data suggest poor MNS in Africa and confirms the importance of the first 1000 days as a critical period for nutritional intervention to improve growth, birth outcomes and potential future health risk. However, there is a lack of data beyond birth and a need for longitudinal data through infancy to 2 years of age.

scholarly journals A comparative study of the effect of body mass index on pregnancy outcomes in normal and overweight women

2017 ◽  
Vol 6 (4) ◽  
pp. 1550
Author(s):  
Seeniammal P. ◽  
Chellamma V. K. ◽  
Umadevi N.
Keyword(s):  
Comparative Study ◽  
Maternal Obesity ◽  
Gestational Hypertension ◽  
Fetal Outcome ◽  
Overweight And Obesity ◽  
Health Concern ◽  
Accurate Information ◽  
Obese Women ◽  
Increased Risk ◽  
Maternal Overweight

Background: Maternal obesity has been reported as a risk factor for various antepartum, intrapartum, postpartum and neonatal complications. Increasing rates of overweight among pregnant women are a significant public health concern with various implications for prenatal care and supervision of delivery. Therefore, the present study is to determine the adverse materno-fetal outcome in primigravid overweight and obese women delivering singleton babies.Methods: A prospective comparative study was conducted for a year at IMCH, Medical College, Calicut. Primigravid women with a singleton uncomplicated pregnancy with cephalic presentation at ≥37 weeks of gestation with accurate information regarding height and weight recorded at the booking visit were included in the study. Comparisons were made between 100 women with BMI >25 and 200 women with BMI 18.5-24.9. Statistical analysis was done using SPSS version 16.0. Data was analysed by Pearson Chi square test and Fisher’s exact test.Results: Overweight mothers are at increased risk quoted as relative risk (RR) and 95% confidence intervals (CI) of adverse materno-fetal outcomes. Gestational hypertension RR 2.39 (CI 1.65-3.47), Gestational diabetes RR 2.67(CI 0.95-7.48), induction of labour RR 2.35 (CI 1.4-3.95), Cesarean section RR 5.73 (CI 3.76-8.73), macrosomia RR 14 (CI 1.75-112.23), NICU admissions RR 4.51(CI 2.61-7.84),perineal lacerations RR 4.72 (CI 1.15-20.4), wound infection RR 2.97 (CI 1.06-8.41), and prolonged hospital stay.Conclusions: It is clearly evident from the study that maternal overweight and obesity is associated with adverse materno-fetal outcome.

scholarly journals Four cases of Dysthymic Disorder and General Malaise Successfully Treated with Traditional Herbal (Kampo) Medicines: Kamiuntanto

2010 ◽  
Vol 5 ◽  
pp. IMI.S4586 ◽  
Author(s):  
Toshiaki Kogure ◽  
Takeshi Tatsumi ◽  
Yuko Oku
Keyword(s):  
Mental Disorders ◽  
Present Report ◽  
Dysthymic Disorder ◽  
Major Depressive ◽  
Statistical Manual ◽  
Diagnostic And Statistical Manual ◽  
Ancient Times ◽  
Dsm Iv ◽  
Disorder Treatment

Traditional herbal (Kampo) medicines have been used since ancient times to treat patients with mental disorders. In the present report, we describe four patients with dysthymia successfully treated with Kampo medicines: Kamiuntanto (KUT). These four patients fulfilled the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) criteria for dysthymic disorder with easy fatigability and sleeplessness, but did not fulfill the criteria for major depressive disorder. Treatment with KUT relieved depressive status, fatigue and sleeplessness in these patients. As a result, their QOL (quality of life) was considerably improved. KUT may be useful as an additional or alternative treatment for dysthymia, especially in the field of primary health care.

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