scholarly journals Revealing Donor Substrate-Dependent Mechanistic Control on DXPS, an Enzyme in Bacterial Central Metabolism

Biochemistry ◽  
2021 ◽  
Author(s):  
Melanie L. Johnston ◽  
Caren L. Freel Meyers
Keyword(s):  
Central Metabolism ◽  
Donor Substrate

Development of Experimental and Theoretical Methodology for Determination of Characteristics of central Metabolism Regulation in Cancer Cells

2012 ◽  
Vol 120 (10) ◽  
Author(s):  
D Shaumarova ◽  
A Benito ◽  
J Centelles ◽  
S Marin Martinez ◽  
V Selivanov ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Central Metabolism ◽  
Metabolism Regulation

scholarly journals Dynamic Labeling Reveals Temporal Changes in Carbon Re-Allocation within the Central Metabolism of Developing Apple Fruit

2017 ◽  
Vol 8 ◽  
Author(s):  
Wasiye F. Beshir ◽  
Victor B. M. Mbong ◽  
Maarten L. A. T. M. Hertog ◽  
Annemie H. Geeraerd ◽  
Wim Van den Ende ◽  
...  
Keyword(s):  
Apple Fruit ◽  
Temporal Changes ◽  
Central Metabolism

scholarly journals Oxidative Stress-Induced Alteration of Plant Central Metabolism

Life ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 304
Author(s):  
Tatyana Savchenko ◽  
Konstantin Tikhonov
Keyword(s):  
Oxidative Stress ◽  
Stress Responses ◽  
Tricarboxylic Acid Cycle ◽  
Strong Dependence ◽  
Plant Stress ◽  
Metabolite Profile ◽  
Agricultural Practice ◽  
Central Metabolism ◽  
Metabolic Markers ◽  
Sugar Derivatives

Oxidative stress is an integral component of various stress conditions in plants, and this fact largely determines the substantial overlap in physiological and molecular responses to biotic and abiotic environmental challenges. In this review, we discuss the alterations in central metabolism occurring in plants experiencing oxidative stress. To focus on the changes in metabolite profile associated with oxidative stress per se, we primarily analyzed the information generated in the studies based on the exogenous application of agents, inducing oxidative stress, and the analysis of mutants displaying altered oxidative stress response. Despite of the significant variation in oxidative stress responses among different plant species and tissues, the dynamic and transient character of stress-induced changes in metabolites, and the strong dependence of metabolic responses on the intensity of stress, specific characteristic changes in sugars, sugar derivatives, tricarboxylic acid cycle metabolites, and amino acids, associated with adaptation to oxidative stress have been detected. The presented analysis of the available data demonstrates the oxidative stress-induced redistribution of metabolic fluxes targeted at the enhancement of plant stress tolerance through the prevention of ROS accumulation, maintenance of the biosynthesis of indispensable metabolites, and production of protective compounds. This analysis provides a theoretical basis for the selection/generation of plants with improved tolerance to oxidative stress and the development of metabolic markers applicable in research and routine agricultural practice.

scholarly journals Oil Pollution Affects the Central Metabolism of Keystone Vachellia (Acacia) Trees

2021 ◽  
Vol 13 (12) ◽  
pp. 6660
Author(s):  
Marco Ferrante ◽  
Anuma Dangol ◽  
Shoshana Didi-Cohen ◽  
Gidon Winters ◽  
Vered Tzin ◽  
...  
Keyword(s):  
Oil Spills ◽  
Oil Pollution ◽  
Keystone Species ◽  
Desert Ecosystem ◽  
Arid Environments ◽  
Central Metabolism ◽  
Adult Trees ◽  
Metabolite Profiles ◽  
One Year

Vachellia (formerly Acacia) trees are native to arid environments in Africa and the Arabian Peninsula, where they often support the local animal and plant communities acting as keystone species. The aim of this study was to examine whether oil pollution affected the central metabolism of the native keystone trees Vachellia tortilis (Forssk.) and V. raddiana (Savi), as either adults or seedlings. The study was conducted in the Evrona Nature Reserve, a desert ecosystem in southern Israel where two major oil spills occurred in 1975 and in 2014. Leaf samples were collected to analyze the central metabolite profiles from oil-polluted and unpolluted adult trees and from Vachellia seedlings growing in oil-polluted and unpolluted soils in an outdoor setup. We found that oil pollution had a stronger effect on one-year-old seedlings than on adult trees, reducing the levels of amino acids, sugars, and organic acids. While adult trees are mildly affected by oil pollution, the effects on young seedlings can cause a long-term reduction in the population of these keystone desert trees, ultimately threatening this entire ecosystem.

Sign in / Sign up

Export Citation Format

Share Document