Selective and Efficient Photoinactivation of Intracellular Staphylococcus aureus and MRSA with Little Accumulation of Drug Resistance: Application of a Ru(II) Complex with Photolabile Ligands

2021 ◽  
Author(s):  
Weize Sun ◽  
Yao Jian ◽  
Mengxue Zhou ◽  
Yishan Yao ◽  
Na Tian ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Drug Resistance

Reversal of Multi-Drug Resistance in Staphylococcus aureus by Natural Product-Way Forward

2016 ◽  
Vol 13 (7) ◽  
pp. 668-675
Author(s):  
Saba Farooq ◽  
. Atia-tul-Wahab ◽  
Ali Azarpira ◽  
. Atta-ur-Rahman ◽  
M. Iqbal Choudhary
Keyword(s):  
Staphylococcus Aureus ◽  
Drug Resistance ◽  
Natural Product ◽  
Multi Drug Resistance

scholarly journals Modulation of drug resistance and biofilm formation of Staphylococcus aureus isolated from the oral cavity of Tunisian children

2017 ◽  
Vol 21 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Tarek Zmantar ◽  
Rihab Ben Slama ◽  
Kais Fdhila ◽  
Bochra Kouidhi ◽  
Amina Bakhrouf ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Drug Resistance ◽  
Oral Cavity ◽  
Biofilm Formation

MRSA REMAINS A GREAT PRIORITY DUE TO THE TREMENDOUS MORTALITY --- A BIRD'S EYE VIEW

2021 ◽  
pp. 114-118
Author(s):  
Raghavendra Rao M. V ◽  
Mubasheer Ali ◽  
Yogendra Kumar Verma ◽  
Dilip Mathai ◽  
Tina Priscilla ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Drug Resistance ◽  
Chronic Infection ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Multiple Drug Resistance ◽  
Multiple Drug ◽  
High Dose ◽  
Benzyl Penicillin ◽  
Methicillin Resistant ◽  
Antimicrobial Sensitivity

Methicillin-resistant Staphylococcus aureus (MRSA) is difcult to treat with methicillin, amoxicillin, penicillin, oxacillin, and other commonly used antibiotics because of its resistance. Staphylococcus organisms rapidly develop drug resistance as many as 50% of the domiciliary and 80% of the hospital strains are now penicillin resistant. Staphylococcus aureus also show multiple drug resistance. Therefore, Staphylococcal isolates should always be tested for antimicrobial sensitivity and chronic infection should be treated by more than one drug. Before 1960,when methicillin, is the rst penicillin's-resistant penicillin's, was brought into use, about 1%of the strains of the Staphylococcus aureus were "methicillin resistant" and by 1970 in Britain their proportion has risen to about 5%.These strains are tolerant of, low therapeutic concentrations of methicillin, cloxacillin, benzyl penicillin and ampicillin.They do not destroy methicillin and cloxacillin, but most of them are penicillinase-producing as well as being "methicillin resistant" and therefore inactivate benzyl penicillin and ampicillin. Its resistance is uncertain since infections may be cured with a high dose of methicillin.

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