Venom Peptide Repertoire of the European Myrmicine Ant Manica rubida: Identification of Insecticidal Toxins

2020 ◽  
Vol 19 (4) ◽  
pp. 1800-1811 ◽  
Author(s):  
Axel Touchard ◽  
Samira R. Aili ◽  
Nathan Téné ◽  
Valentine Barassé ◽  
Christophe Klopp ◽  
...  
Keyword(s):  
Venom Peptide ◽  
Insecticidal Toxins ◽  
Manica Rubida

Autocrine‐Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries

2016 ◽  
Vol 55 (32) ◽  
pp. 9306-9310 ◽  
Author(s):  
Hongkai Zhang ◽  
Mingjuan Du ◽  
Jia Xie ◽  
Xiao Liu ◽  
Jingying Sun ◽  
...  
Keyword(s):  
Ion Channels ◽  
Peptide Libraries ◽  
Venom Peptide ◽  
Selection Of

scholarly journals Precursor of a Novel Scorpion Venom Peptide (BmKn1) with no Disulfide Bridge from Buthus martensii Karsch

IUBMB Life ◽  
2001 ◽  
Vol 51 (2) ◽  
pp. 117-120
Author(s):  
Xian-Chun Zeng, Wen-Xin Li, San-Xia Wang, Shu
Keyword(s):  
Disulfide Bridge ◽  
Scorpion Venom ◽  
Venom Peptide

scholarly journals Apoptotic Effects of Mount Bulgar Viper (Montivipera bulgardaghica) PLA2 and SVMPs Venom Peptide fractions on HeLa and A549 Cancer Cells

Proceedings ◽  
2017 ◽  
Vol 1 (10) ◽  
pp. 1049 ◽  
Author(s):  
Yalcin Erzurumlu ◽  
Daniel Petras ◽  
Bayram Goçmen ◽  
Benjamin-Florian Hempel ◽  
Paul Heiss ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Venom Peptide ◽  
Apoptotic Effects ◽  
Peptide Fractions

Autocrine‐Based Selection of Drugs That Target Ion Channels from Combinatorial Venom Peptide Libraries

2016 ◽  
Vol 128 (32) ◽  
pp. 9452-9456
Author(s):  
Hongkai Zhang ◽  
Mingjuan Du ◽  
Jia Xie ◽  
Xiao Liu ◽  
Jingying Sun ◽  
...  
Keyword(s):  
Ion Channels ◽  
Peptide Libraries ◽  
Venom Peptide ◽  
Selection Of

scholarly journals Plant Insecticidal Toxins in Ecological Networks

Toxins ◽  
2012 ◽  
Vol 4 (4) ◽  
pp. 228-243 ◽  
Author(s):  
Sébastien Ibanez ◽  
Christiane Gallet ◽  
Laurence Després
Keyword(s):  
Ecological Networks ◽  
Insecticidal Toxins

scholarly journals Display of Biologically Functional Insecticidal Toxin on the Surface of λ Phage

2004 ◽  
Vol 70 (11) ◽  
pp. 6587-6594 ◽  
Author(s):  
Susana V�lchez ◽  
Juliette Jacoby ◽  
David J. Ellar
Keyword(s):  
Selection Pressure ◽  
Diamondback Moth ◽  
Combinatorial Libraries ◽  
Amino Terminus ◽  
Display System ◽  
Agricultural Pests ◽  
Binding Properties ◽  
Insecticidal Toxin ◽  
Cry Toxins ◽  
Insecticidal Toxins

ABSTRACT The successful use of Bacillus thuringiensis insecticidal toxins to control agricultural pests could be undermined by the evolution of insect resistance. Under selection pressure in the laboratory, a number of insects have gained resistance to the toxins, and several cases of resistance in the diamondback moth have been reported from the field. The use of protein engineering to develop novel toxins active against resistant insects could offer a solution to this problem. The display of proteins on the surface of phages has been shown to be a powerful technology to search for proteins with new characteristics from combinatorial libraries. However, this potential of phage display to develop Cry toxins with new binding properties and new target specificities has hitherto not been realized because of the failure of displayed Cry toxins to bind their natural receptors. In this work we describe the construction of a display system in which the Cry1Ac toxin is fused to the amino terminus of the capsid protein D of bacteriophage lambda. The resultant phage was viable and infectious, and the displayed toxin interacted successfully with its natural receptor.

scholarly journals Transcriptional Analysis of the Toxin-Coding Plasmid pBtoxis from Bacillus thuringiensis subsp. israelensis

2006 ◽  
Vol 72 (3) ◽  
pp. 1771-1776 ◽  
Author(s):  
Claudia Stein ◽  
Gareth W. Jones ◽  
Tanya Chalmers ◽  
Colin Berry
Keyword(s):  
Gene Regulation ◽  
Bacillus Thuringiensis ◽  
Transcriptional Regulators ◽  
Transcriptional Analysis ◽  
Host Bacterium ◽  
Large Plasmid ◽  
Coding Sequences ◽  
Physiological Processes ◽  
Insecticidal Toxins

ABSTRACT In Bacillus thuringiensis subsp. israelensis all of the insecticidal toxins are encoded on a single, large plasmid, pBtoxis. Sequencing of this plasmid revealed 125 potential coding sequences, many of which have predicted functions in gene regulation and physiological processes, such as germination. As a first step in understanding the possible role of pBtoxis in its host bacterium, a survey of the transcription of genes with predicted functions was carried out. Whereas many coding sequences, including those previously identified as probable pseudogenes, were not transcribed, mRNA was detected for 29 of the 40 sequences surveyed. Several of these sequences, including eight with similarities to the sequences of known transcriptional regulators, may influence wider gene regulation and thus may alter the phenotype of the host bacterium.

scholarly journals A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles

2018 ◽  
Vol 294 (1) ◽  
pp. 182-194 ◽  
Author(s):  
Fangfang Li ◽  
Yange Lang ◽  
Zhenglin Ji ◽  
Zhiqiang Xia ◽  
Yuewen Han ◽  
...  
Keyword(s):  
Scorpion Venom ◽  
Late Entry ◽  
Venom Peptide ◽  
Acidic Organelles
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