MRI Guided Magneto-chemotherapy with High-Magnetic-Moment Iron Oxide Nanoparticles for Cancer Theranostics

2020 ◽  
Vol 3 (4) ◽  
pp. 2305-2313 ◽  
Author(s):  
Ashwini Salunkhe ◽  
Vishwajeet Khot ◽  
S. I. Patil ◽  
Syed A.M. Tofail ◽  
Joanna Bauer ◽  
...  
2020 ◽  
Vol 2 (10) ◽  
pp. 4510-4521 ◽  
Author(s):  
Regina Bleul ◽  
Abdulkader Baki ◽  
Christian Freese ◽  
Hendrik Paysen ◽  
Olaf Kosch ◽  
...  

A micromixer platform for continuously manufactured single-core iron oxide nanoparticles for diagnostic and therapeutic applications contributing to translational research.


RSC Advances ◽  
2016 ◽  
Vol 6 (102) ◽  
pp. 99948-99959 ◽  
Author(s):  
Ganeshlenin Kandasamy ◽  
Sreeraj Surendran ◽  
Anindita Chakrabarty ◽  
S. N. Kale ◽  
Dipak Maity

We report a one-step facile synthesis of novel water-soluble and functionalized SPIONs, which could be promising candidates for cancer theranostics.


Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2178
Author(s):  
Theodora Krasia-Christoforou ◽  
Vlad Socoliuc ◽  
Kenneth D. Knudsen ◽  
Etelka Tombácz ◽  
Rodica Turcu ◽  
...  

Iron oxide nanoparticles are the basic components of the most promising magnetoresponsive nanoparticle systems for medical (diagnosis and therapy) and bio-related applications. Multi-core iron oxide nanoparticles with a high magnetic moment and well-defined size, shape, and functional coating are designed to fulfill the specific requirements of various biomedical applications, such as contrast agents, heating mediators, drug targeting, or magnetic bioseparation. This review article summarizes recent results in manufacturing multi-core magnetic nanoparticle (MNP) systems emphasizing the synthesis procedures, starting from ferrofluids (with single-core MNPs) as primary materials in various assembly methods to obtain multi-core magnetic particles. The synthesis and functionalization will be followed by the results of advanced physicochemical, structural, and magnetic characterization of multi-core particles, as well as single- and multi-core particle size distribution, morphology, internal structure, agglomerate formation processes, and constant and variable field magnetic properties. The review provides a comprehensive insight into the controlled synthesis and advanced structural and magnetic characterization of multi-core magnetic composites envisaged for nanomedicine and biotechnology.


2018 ◽  
Vol 2 (1) ◽  

Superparamagnetic iron oxide nanoparticles (SPIONs) have found extensive applications in both cancer therapy and diagnosis (theranostics) due to their intrinsic magnetic properties. SPIONs can be applied as contrast agents in magnetic resonance imaging while they are considered as efficacious drug carriers for targeted therapeutic systems as well as hyperthermia therapy. In this article, recent advances in application of SPIONs in the realm of cancer theranostics are reviewed. Moreover, biosafety issues arising from SPION application are briefly mentioned.


2017 ◽  
Vol 5 (21) ◽  
pp. 3927-3939 ◽  
Author(s):  
Ramesh Nandi ◽  
Snehasis Mishra ◽  
Tuhin Kumar Maji ◽  
Krishnendu Manna ◽  
Prasenjit Kar ◽  
...  

Folic acid functionalized iron oxide nanoparticles for colorectal cancer theranostics application.


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