Silk Fibroin/Collagen Blended Membrane Fabricated via a Green Papermaking Method for Potential Guided Bone Regeneration Application: In Vitro and In Vivo Evaluation

2021 ◽  
Author(s):  
Dandan Luo ◽  
Chenxue Yao ◽  
Rui Zhang ◽  
Ruibo Zhao ◽  
M. Zubair Iqbal ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Silk Fibroin ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation ◽  
Blended Membrane

In Vitro and In Vivo Evaluation of a nHA/PA66 Composite Membrane for Guided Bone Regeneration

2011 ◽  
Vol 22 (1-3) ◽  
pp. 263-275 ◽  
Author(s):  
Jidong Li ◽  
Yi Man ◽  
Yi Zuo ◽  
Li Zhang ◽  
Cui Huang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Composite Membrane ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation

scholarly journals In Vitro Physico-Chemical Characterization and Standardized In Vivo Evaluation of Biocompatibility of a New Synthetic Membrane for Guided Bone Regeneration

Materials ◽  
2019 ◽  
Vol 12 (7) ◽  
pp. 1186
Author(s):  
Lívia da Costa Pereira ◽  
Carlos Fernando de Almeida Barros Mourão ◽  
Adriana Terezinha Neves Novellino Alves ◽  
Rodrigo Figueiredo de Brito Resende ◽  
Marcelo José Pinheiro Guedes de Uzeda ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Chemical Properties ◽  
Chemical Characterization ◽  
Guided Bone Regeneration ◽  
Tissue Reaction ◽  
In Vivo Evaluation ◽  
Physico Chemical ◽  
Tissue Reactions

This study’s aim was to evaluate the biocompatibility and bioabsorption of a new membrane for guided bone regeneration (polylactic-co-glycolic acid associated with hydroxyapatite and β-tricalcium phosphate) with three thicknesses (200, 500, and 700 µm) implanted in mice subcutaneously. Scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and the quantification of carbon, hydrogen and nitrogen were used to characterize the physico-chemical properties. One hundred Balb-C mice were divided into 5 experimental groups: Group 1—Sham (without implantation); Group 2—200 μm; Group 3—500 μm; Group 4—700 μm; and Group 5—Pratix®. Each group was subdivided into four experimental periods (7, 30, 60 and 90 days). Samples were collected and processed for histological and histomorphometrical evaluation. The membranes showed no moderate or severe tissue reactions during the experimental periods studied. The 500-μm membrane showed no tissue reaction during any experimental period. The 200-μm membrane began to exhibit fragmentation after 30 days, while the 500-μm and 700-µm membranes began fragmentation at 90 days. All membranes studied were biocompatible and the 500 µm membrane showed the best results for absorption and tissue reaction, indicating its potential for clinical guided bone regeneration.

In vitro and in vivo evaluation of e-PTFE and alkali-cellulose membranes for guided bone regeneration

2001 ◽  
Vol 12 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Luiz A. Salata ◽  
Paul V. Hatton ◽  
A. Jane Devlin ◽  
Geoffrey T. Craig ◽  
Ian M. Brook
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation ◽  
Alkali Cellulose ◽  
Cellulose Membranes

scholarly journals In vitro and in vivo evaluation of synthetic resorbable membrane for guided bone regeneration

2019 ◽  
Author(s):  
Yusuke Sakaguchi ◽  
Kyohei Toyonaga ◽  
Yuuhiro Sakai ◽  
Emiko Arima ◽  
Shinichi Kato ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation

scholarly journals In vitro and in vivo evaluation of synthetic resorbable membrane for guided bone regeneration

2019 ◽  
Vol 30 (S19) ◽  
pp. 57-57
Author(s):  
Yusuke Sakaguchi ◽  
Toyonaga Kyohei ◽  
Sakai Yuuhiro ◽  
Kato Shinichi ◽  
Arima Emiko ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation

scholarly journals Zn-Containing Membranes for Guided Bone Regeneration in Dentistry

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1797
Author(s):  
Manuel Toledano ◽  
Marta Vallecillo-Rivas ◽  
María T. Osorio ◽  
Esther Muñoz-Soto ◽  
Manuel Toledano-Osorio ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Regeneration ◽  
Bone Healing ◽  
Bone Repair ◽  
Complex Modulus ◽  
Bacterial Colonization ◽  
Guided Bone Regeneration ◽  
M2 Macrophage

Barrier membranes are employed in guided bone regeneration (GBR) to facilitate bone in-growth. A bioactive and biomimetic Zn-doped membrane with the ability to participate in bone healing and regeneration is necessary. The aim of the present study is to state the effect of doping the membranes for GBR with zinc compounds in the improvement of bone regeneration. A literature search was conducted using electronic databases, such as PubMed, MEDLINE, DIMDI, Embase, Scopus and Web of Science. A narrative exploratory review was undertaken, focusing on the antibacterial effects, physicochemical and biological properties of Zn-loaded membranes. Bioactivity, bone formation and cytotoxicity were analyzed. Microstructure and mechanical properties of these membranes were also determined. Zn-doped membranes have inhibited in vivo and in vitro bacterial colonization. Zn-alloy and Zn-doped membranes attained good biocompatibility and were found to be non-toxic to cells. The Zn-doped matrices showed feasible mechanical properties, such as flexibility, strength, complex modulus and tan delta. Zn incorporation in polymeric membranes provided the highest regenerative efficiency for bone healing in experimental animals, potentiating osteogenesis, angiogenesis, biological activity and a balanced remodeling. Zn-loaded membranes doped with SiO2 nanoparticles have performed as bioactive modulators provoking an M2 macrophage increase and are a potential biomaterial for promoting bone repair. Zn-doped membranes have promoted pro-healing phenotypes.

scholarly journals In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration

Nanomaterials ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 46 ◽  
Author(s):  
Manabu Tanaka ◽  
Yoshinori Sato ◽  
Mei Zhang ◽  
Hisao Haniu ◽  
Masanori Okamoto ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Bone Regeneration ◽  
Three Dimensional ◽  
In Vivo Evaluation ◽  
Multi Walled Carbon Nanotube

Dual growth factor loaded nonmulberry silk fibroin/carbon nanofiber composite 3D scaffolds for in vitro and in vivo bone regeneration

Biomaterials ◽  
2017 ◽  
Vol 136 ◽  
pp. 67-85 ◽  
Author(s):  
Deboki Naskar ◽  
Ananta K. Ghosh ◽  
Mahitosh Mandal ◽  
Piyali Das ◽  
Samit K. Nandi ◽  
...  
Keyword(s):  
Growth Factor ◽  
Bone Regeneration ◽  
Silk Fibroin ◽  
Carbon Nanofiber ◽  
Nanofiber Composite ◽  
3D Scaffolds
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