scholarly journals Impact of Warhead Modulations on the Covalent Inhibition of SARS-CoV-2 Mpro Explored by QM/MM Simulations

ACS Catalysis ◽  
2021 ◽  
pp. 698-708
Author(s):  
Sergio Martí ◽  
Kemel Arafet ◽  
Alessio Lodola ◽  
Adrian J. Mulholland ◽  
Katarzyna Świderek ◽  
...  
Keyword(s):  
Covalent Inhibition

Covalent inhibition of botulinum neurotoxin A – Exploration of warhead reactivity and function using a bifunctional approach

Toxicon ◽  
2021 ◽  
Vol 190 ◽  
pp. S72-S73
Author(s):  
Lewis D. Turner ◽  
Alexander L. Nielsen ◽  
Lucy Lin ◽  
Sabine Pellett ◽  
Takashi Sugane ◽  
...  
Keyword(s):  
Botulinum Neurotoxin ◽  
Botulinum Neurotoxin A ◽  
Covalent Inhibition ◽  
And Function

Discovery of 4,4′-Dipyridylsulfide Analogs as “Switchable Electrophiles” for Covalent Inhibition

2021 ◽  
Vol 16 (2) ◽  
pp. 264-269
Author(s):  
Yeong-Chan Ahn ◽  
Valerie K. May ◽  
Guy C. Bedford ◽  
Alfred A. Tuley ◽  
Walter Fast
Keyword(s):  
Covalent Inhibition

scholarly journals Determining Cysteines Available for Covalent Inhibition Across the Human Kinome

2017 ◽  
Vol 60 (7) ◽  
pp. 2879-2889 ◽  
Author(s):  
Zheng Zhao ◽  
Qingsong Liu ◽  
Spencer Bliven ◽  
Lei Xie ◽  
Philip E. Bourne
Keyword(s):  
Covalent Inhibition ◽  
Human Kinome

scholarly journals Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Weiwu Ren ◽  
Robert Pengelly ◽  
Marco Farren-Dai ◽  
Saeideh Shamsi Kazem Abadi ◽  
Verena Oehler ◽  
...  
Keyword(s):  
Atomic Level ◽  
Glycoside Hydrolases ◽  
Covalent Inhibition

Covalent Inhibition of New Delhi Metallo-β-Lactamase-1 (NDM-1) by Cefaclor

ChemBioChem ◽  
2014 ◽  
Vol 15 (17) ◽  
pp. 2541-2548 ◽  
Author(s):  
Pei W. Thomas ◽  
Michael Cammarata ◽  
Jennifer S. Brodbelt ◽  
Walter Fast
Keyword(s):  
New Delhi ◽  
Covalent Inhibition

scholarly journals Inside Cover: Covalent Inhibition of New Delhi Metallo-β-Lactamase-1 (NDM-1) by Cefaclor (ChemBioChem 17/2014)

ChemBioChem ◽  
2014 ◽  
Vol 15 (17) ◽  
pp. 2474-2474
Author(s):  
Pei W. Thomas ◽  
Michael Cammarata ◽  
Jennifer S. Brodbelt ◽  
Walter Fast
Keyword(s):  
New Delhi ◽  
Covalent Inhibition

Targeted Covalent Inhibition of Grb2–Sos1 Interaction through Proximity-Induced Conjugation in Breast Cancer Cells

2017 ◽  
Vol 14 (5) ◽  
pp. 1548-1557 ◽  
Author(s):  
Yongsheng Yu ◽  
Yunyu Nie ◽  
Qian Feng ◽  
Jiale Qu ◽  
Rui Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Covalent Inhibition

scholarly journals Reversible Covalent Inhibition of eEF-2K by Carbonitriles

ChemBioChem ◽  
2014 ◽  
Vol 15 (16) ◽  
pp. 2435-2442 ◽  
Author(s):  
Ashwini K. Devkota ◽  
Ramakrishna Edupuganti ◽  
Chunli Yan ◽  
Yue Shi ◽  
Jiney Jose ◽  
...  
Keyword(s):  
Covalent Inhibition ◽  
Reversible Covalent
Sign in / Sign up

Export Citation Format

Share Document