Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I

2008 ◽  
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Annamaria Martorana ◽  
Paola Barraja ◽  
Alessandra Montalbano ◽  
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Topoisomerase I ◽  
Antitumor Agents ◽  
Tubulin Polymerization ◽  
Quinoxaline Derivatives ◽  
Dual Inhibition

Benzothienoquinazolinones as new multi-target scaffolds: Dual inhibition of human Topoisomerase I and tubulin polymerization

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Anna Caruso ◽  
Maria Antonietta Occhiuzzi ◽  
Domenico Iacopetta ◽  
Alexia Barbarossa ◽  
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Keyword(s):  
Topoisomerase I ◽  
Tubulin Polymerization ◽  
Dual Inhibition

Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent

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pp. 2009-2019 ◽  
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Jang-Yang Chang ◽  
Hsing-Pang Hsieh ◽  
Wen-Yu Pan ◽  
Jing-Ping Liou ◽  
Shian-Jy Bey ◽  
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Keyword(s):  
Topoisomerase I ◽  
Cytotoxic Agent ◽  
Tubulin Polymerization ◽  
Dual Inhibition

Novel securinine derivatives as topoisomerase I based antitumor agents

2016 ◽  
Vol 122 ◽  
pp. 149-163 ◽  
Author(s):  
Wen Hou ◽  
Zhen-Ya Wang ◽  
Cheng-Kang Peng ◽  
Jing Lin ◽  
Xin Liu ◽  
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Keyword(s):  
Topoisomerase I ◽  
Antitumor Agents

Methylenedioxy- and Ethylenedioxy-Fused Indolocarbazoles: Potent Human Topoisomerase I Inhibitors and Antitumor Agents

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Author(s):  
David E. Zembower ◽  
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Ali Koohang ◽  
Mary J. Kuffel ◽  
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Keyword(s):  
Topoisomerase I ◽  
Antitumor Agents ◽  
Topoisomerase I Inhibitors

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Virtual Screening ◽  
Topoisomerase I ◽  
Antitumor Agents ◽  
Topoisomerase I Inhibitor ◽  
Selection Of
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