scholarly journals 1-Aryl-3-(1-acylpiperidin-4-yl)urea Inhibitors of Human and Murine Soluble Epoxide Hydrolase: Structure−Activity Relationships, Pharmacokinetics, and Reduction of Inflammatory Pain

2010 ◽  
Vol 53 (19) ◽  
pp. 7067-7075 ◽  
Author(s):  
Tristan E. Rose ◽  
Christophe Morisseau ◽  
Jun-Yan Liu ◽  
Bora Inceoglu ◽  
Paul D. Jones ◽  
...  
Keyword(s):  
Inflammatory Pain ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Structure–activity relationships of substituted oxyoxalamides as inhibitors of the human soluble epoxide hydrolase

2014 ◽  
Vol 22 (3) ◽  
pp. 1163-1175 ◽  
Author(s):  
In-Hae Kim ◽  
In-Hee Lee ◽  
Hisashi Nishiwaki ◽  
Bruce D. Hammock ◽  
Kosuke Nishi
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure–activity relationships of amide–phosphonate derivatives as inhibitors of the human soluble epoxide hydrolase

2015 ◽  
Vol 23 (22) ◽  
pp. 7199-7210 ◽  
Author(s):  
In-Hae Kim ◽  
Yong-Kyu Park ◽  
Hisashi Nishiwaki ◽  
Bruce D. Hammock ◽  
Kosuke Nishi
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Structure–activity relationships of the plasminogen modulator SMTP with respect to the inhibition of soluble epoxide hydrolase

2015 ◽  
Vol 68 (11) ◽  
pp. 685-690 ◽  
Author(s):  
Naoki Matsumoto ◽  
Eriko Suzuki ◽  
Kota Tsujihara ◽  
Yuuichi Nishimura ◽  
Keiji Hasumi
Keyword(s):  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain

Life Sciences ◽  
2006 ◽  
Vol 79 (24) ◽  
pp. 2311-2319 ◽  
Author(s):  
Bora Inceoglu ◽  
Steven L. Jinks ◽  
Kara R. Schmelzer ◽  
Troy Waite ◽  
In Hae Kim ◽  
...  
Keyword(s):  
Rat Model ◽  
Inflammatory Pain ◽  
Mechanical Allodynia ◽  
Epoxide Hydrolase ◽  
Thermal Hyperalgesia ◽  
Soluble Epoxide Hydrolase

scholarly journals Orally Available Soluble Epoxide Hydrolase/Phosphodiesterase 4 Dual Inhibitor Treats Inflammatory Pain

2018 ◽  
Vol 61 (8) ◽  
pp. 3541-3550 ◽  
Author(s):  
René Blöcher ◽  
Karen M. Wagner ◽  
Raghavender R. Gopireddy ◽  
Todd R. Harris ◽  
Hao Wu ◽  
...  
Keyword(s):  
Inflammatory Pain ◽  
Epoxide Hydrolase ◽  
Soluble Epoxide Hydrolase ◽  
Dual Inhibitor ◽  
Phosphodiesterase 4
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