scholarly journals Discovery and optimization of enantioselective catalysts through chemoinformatics

Author(s):  
Scott Eric Denmark
2020 ◽  
Vol 24 (7) ◽  
pp. 746-773
Author(s):  
Péter Bakó ◽  
Tamás Nemcsok ◽  
Zsolt Rapi ◽  
György Keglevich

: Many catalysts were tested in asymmetric Michael additions in order to synthesize enantioenriched products. One of the most common reaction types among the Michael reactions is the conjugated addition of malonates to enones making it possible to investigate the structure–activity relationship of the catalysts. The most commonly used Michael acceptors are chalcone, substituted chalcones, chalcone derivatives, cyclic enones, while typical donors may be dimethyl, diethyl, dipropyl, diisopropyl, dibutyl, di-tert-butyl and dibenzyl malonates. This review summarizes the most important enantioselective catalysts applied in these types of reactions.


Polymer ◽  
2008 ◽  
Vol 49 (6) ◽  
pp. 1512-1519 ◽  
Author(s):  
Chien-An Chen ◽  
Kuo-Hui Wu ◽  
Han-Mou Gau

ChemInform ◽  
2008 ◽  
Vol 39 (42) ◽  
Author(s):  
Hiroshi Naka ◽  
Nobuhiko Kanase ◽  
Masahiro Ueno ◽  
Yoshinori Kondo

Author(s):  
Frédéric Taran ◽  
Cécile Gauchet ◽  
Barbara Mohar ◽  
Stéphane Meunier ◽  
Alain Valleix ◽  
...  

2001 ◽  
Vol 67 (4) ◽  
pp. 389-396 ◽  
Author(s):  
Manfred T. Reetz ◽  
Klaus M. Kühling ◽  
Stephanie Wilensek ◽  
Heribert Husmann ◽  
Ulrich W. Häusig ◽  
...  

2021 ◽  
pp. 591-603
Author(s):  
Anton Vidal‐Ferran

RSC Advances ◽  
2018 ◽  
Vol 8 (59) ◽  
pp. 34004-34011 ◽  
Author(s):  
Begum Sharifa Zaithun ◽  
AbdulMalek Emilia ◽  
Tahir Mohamed Ibrahim Mohamed ◽  
Crouse Karen Anne ◽  
Abdul Rahman Mohd Basyaruddin

P5 with the sequence H2N-PGHD-CONH.


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