The Cyanobacterial Cyclic Lipopeptides Puwainaphycins F/G Are Inducing Necrosis via Cell Membrane Permeabilization and Subsequent Unusual Actin Relocalization

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PvD1 was able to inhibit the proliferation of Leishmania amazonensis promastigotes; PvD1 caused cell membrane permeabilization and alterations in the cytoplasmic contents of these cells; PvD1 was internalized in these cells, what suggests a possible intracellular target.


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