Adolescent chronic restraint stress (aCRS) elicits robust depressive-like behavior in freely cycling, adult female rats without increasing anxiety-like behaviors.

2017 ◽  
Vol 25 (2) ◽  
pp. 74-83 ◽  
Author(s):  
Meghan Hibicke ◽  
Martha A. Graham ◽  
Renée L. Hayslett
Keyword(s):  
Adult Female ◽  
Restraint Stress ◽  
Female Rats ◽  
Chronic Restraint Stress

Restraint stress enhances alcohol intake in adolescent female rats but reduces alcohol intake in adolescent male and adult female rats

2017 ◽  
Vol 332 ◽  
pp. 269-279 ◽  
Author(s):  
Aranza Wille-Bille ◽  
Ana Ferreyra ◽  
Martina Sciangula ◽  
Florencia Chiner ◽  
Michael E. Nizhnikov ◽  
...  
Keyword(s):  
Adult Female ◽  
Restraint Stress ◽  
Alcohol Intake ◽  
Female Rats ◽  
Adolescent Male ◽  
Adolescent Female

Chronic restraint stress enhances radial arm maze performance in female rats

2001 ◽  
Vol 904 (2) ◽  
pp. 279-289 ◽  
Author(s):  
Rachel E. Bowman ◽  
Mark C. Zrull ◽  
Victoria N. Luine
Keyword(s):  
Restraint Stress ◽  
Female Rats ◽  
Radial Arm Maze ◽  
Maze Performance ◽  
Chronic Restraint Stress

Effects of Chronic Restraint Stress and Estradiol Replacement on Glutamate Release and Uptake in the Spinal Cord from Ovariectomized Female Rats

2008 ◽  
Vol 34 (3) ◽  
pp. 499-507 ◽  
Author(s):  
Leonardo Machado Crema ◽  
Deusa Vendite ◽  
Ana Paula Horn ◽  
Luisa Amalia Diehl ◽  
Ana Paula Aguiar ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Restraint Stress ◽  
Glutamate Release ◽  
Female Rats ◽  
Chronic Restraint Stress

Effects of Chronic Restraint Stress and 17-β-Estradiol Replacement on Oxidative Stress in the Spinal Cord of Ovariectomized Female Rats

2010 ◽  
Vol 35 (11) ◽  
pp. 1700-1707 ◽  
Author(s):  
Leonardo M. Crema ◽  
Luisa A. Diehl ◽  
Ana P. Aguiar ◽  
Lúcia Almeida ◽  
Fernanda U. Fontella ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Spinal Cord ◽  
Restraint Stress ◽  
Female Rats ◽  
Chronic Restraint Stress

The involvement of Notch1 signaling pathway in mid-aged female rats under chronic restraint stress

2020 ◽  
Vol 738 ◽  
pp. 135313
Author(s):  
Jianying Shen ◽  
Ling Lin ◽  
Linghong Liao ◽  
Wenna Liang ◽  
Xiaoting Yang ◽  
...  
Keyword(s):  
Signaling Pathway ◽  
Restraint Stress ◽  
Female Rats ◽  
Chronic Restraint Stress ◽  
Notch1 Signaling ◽  
Notch1 Signaling Pathway

CORTICOSTEROID-UMSATZ UND CORTICOSTEROID-PRODUKTION BEI RATTEN UNTER DER BEHANDLUNG MIT ANABOLEN STEROIDEN

1965 ◽  
Vol 48 (2) ◽  
pp. 263-271 ◽  
Author(s):  
Herbert Schriefers ◽  
Gerlinde Scharlau ◽  
Franzis Pohl
Keyword(s):  
Production Rate ◽  
Adult Female ◽  
Anabolic Steroids ◽  
Reduction Rate ◽  
Female Rats ◽  
Adrenal Weight ◽  
Hydrogenase Activity ◽  
Anabolic Effect ◽  
Liver Slices

ABSTRACT After the administration of anabolic steroids to adult female rats in daily doses of 1 mg per animal for 14 days, the following parameters were investigated: the rate of the Δ4-5α-hydrogenase-catalyzed cortisone reduction in liver slices and microsomal fractions, the adrenal weight and the in vitro corticosterone production rate. Among the steroids tested, only 17α-methyl-testosterone and 17α-ethyl-19-nor-testosterone were effective in lowering significantly cortisone reduction rate by liver slices with concomitant decreases in microsomal Δ4-5α-hydrogenase-activity. Testosterone, 19-nor-testosterone, 17α-ethinyl-19-nor-testosterone, 17α-methyl-17β-hydroxy-androsta-1,4-dien-3-one and 1-methyl-17β-hydroxy-androst-1-en-3-one were ineffective or only slightly effective. Adrenal weight and absolute corticosterone production rate (μg/60 min per animal) were decreased after treatment with 17α-methyl-testosterone, 17α-ethyl-19-nor-testosterone and 1-methyl-17β-hydroxy-androst-1-en-3-one. Corticosterone production was decreased with 17α-ethinyl-19-nor-testosterone in spite of an unchanged adrenal weight. The relative corticosterone production rate (μg/60 min · 100 mg adrenal) was in any cases unaffected. According to these results there exists – with the exception of 17α-ethinyl-19-nor-testosterone – a strict parallelism between corticosteroid turnover and corticosterone production rate: unchanged turnover is correlated with unchanged corticosterone production rate, while a decreased turnover is correlated with decreased adrenal activity. The protein-anabolic effect of certain anabolic steroids may be partly due to an anti-catabolic action of these compounds resulting from a decreased corticosteroid inactivation and production rate. Possible mechanisms by which anabolic steroids may affect corticosteroid-balance are discussed.

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