Copper-catalyzed regioselective synthesis of furan via tandem cycloaddition of ketone with an unsaturated carboxylic acid under air

2015 ◽  
Vol 13 (1) ◽  
pp. 309-314 ◽  
Author(s):  
Monoranjan Ghosh ◽  
Subhajit Mishra ◽  
Kamarul Monir ◽  
Alakananda Hajra
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Ambient Air ◽  
Regioselective Synthesis ◽  
Unsaturated Carboxylic Acid ◽  
Unsaturated Carboxylic Acids

A catalytic decarboxylative annulation has been developed for the regioselective synthesis of furans by the cycloaddition of ketones with α,β-unsaturated carboxylic acids in ambient air.

N-Heterocyclic carbene-catalyzed [4 + 2] annulation of α,β-unsaturated carboxylic acids: enantioselective synthesis of dihydropyridinones and spirocyclic oxindolodihydropyridinones

2016 ◽  
Vol 3 (1) ◽  
pp. 77-81 ◽  
Author(s):  
Wen-Qiang Jia ◽  
Han-Ming Zhang ◽  
Chun-Lin Zhang ◽  
Zhong-Hua Gao ◽  
Song Ye
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Enantioselective Synthesis ◽  
Unsaturated Carboxylic Acid ◽  
Unsaturated Carboxylic Acids

The N-heterocyclic carbene-catalyzed [4 + 2] annulation of α,β-unsaturated carboxylic acid with hydrazones and isatin-derived imines was developed, affording the corresponding dihydropyridinones, respectively, in good yields with high enantioselectivities.

Stable carboxylic acid derivatized alkoxy silanes

2015 ◽  
Vol 51 (12) ◽  
pp. 2339-2341 ◽  
Author(s):  
A. Feinle ◽  
S. Flaig ◽  
M. Puchberger ◽  
U. Schubert ◽  
N. Hüsing
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
One Pot ◽  
Hydrosilylation Reaction ◽  
Unsaturated Carboxylic Acids ◽  
Organofunctional Silanes ◽  
Alkoxy Groups

A convenient and straightforward one-pot hydrosilylation reaction of different unsaturated carboxylic acids with trialkoxysilanes in the presence of catalytic amounts of platinum(iv) dioxide resulted in excellent yields in organofunctional silanes combining carboxy- and alkoxy groups within one molecule.

scholarly journals Biocatalytic reduction of α,β-unsaturated carboxylic acids to allylic alcohols

2020 ◽  
Vol 22 (12) ◽  
pp. 3927-3939
Author(s):  
Godwin A. Aleku ◽  
George W. Roberts ◽  
David Leys
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Allylic Alcohols ◽  
Unsaturated Carboxylic Acids

Robust in vitro and in vivo carboxylic acid reductase (CAR)-based biocatalytic systems have been developed that enable hydrogenation of α,β-unsaturated carboxylic acids to allylic alcohols and their saturated analogues.

Regioselective Synthesis of Quinolone Antibacterials via Borate Complex of Quinolone Carboxylic Acid

2005 ◽  
Vol 2005 (9) ◽  
pp. 578-579 ◽  
Author(s):  
Majid M. Heravi ◽  
Zeinab S. Jaddi ◽  
Hossein A. Oskooie ◽  
Shahnaz Khaleghi ◽  
Mitra Ghassemzadeh
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Regioselective Synthesis ◽  
Borate Complex ◽  
Borate Complexes ◽  
High Yields

1-substituted 7-chloro-6-fluoro-4-oxo-1,2-dihydroquinoline-3-carboxylic acids were converted to borate complexes. These compounds were treated with piperazine in presence of triethylamine to afford ciprofloxacin and norfloxacin in high yields.

Studies on Chloroplast Membranes. I. 13C Chemical Shifts and Longitudinal Relaxation Times of Carboxylic Acids

1977 ◽  
Vol 30 (4) ◽  
pp. 813 ◽  
Author(s):  
S Johns ◽  
D Leslie ◽  
R Willing ◽  
D Bishop
Keyword(s):  
Carboxylic Acid ◽  
Chemical Shift ◽  
Carboxylic Acids ◽  
Chemical Shifts ◽  
Relaxation Times ◽  
Segmental Motion ◽  
Unsaturated Carboxylic Acids ◽  
Longitudinal Relaxation ◽  
13C Chemical Shift ◽  
The Individual

The 13C chemical shift and longitudinal relaxation time (T1) of the individual carbon atoms in a series of carboxylic acids in CDCl3 solution have been determined. Substituent shift parameters have been derived from the chemical shift data. The relaxation times have been interpreted in terms of increasing segmental motion along the methylene chains of the carboxylic acid molecules which are associated at the carboxylic acid groups in the form of inverted micelles. Differences in the segmental motion between saturated and unsaturated carboxylic acids are rationalized on the grounds of intermolecular interactions between adjacent molecules in the inverted micelle structures.

Synthesis of 3-(Cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8- carboxylic Acids Via an Efficient Three-component Condensation Reaction between Cyclohexylisocyanide and 2-Aminopyridine-3-carboxylic Acid in the Presence of Aromatic Aldehyde

2018 ◽  
Vol 21 (4) ◽  
pp. 298-301 ◽  
Author(s):  
Ghasem Marandi
Keyword(s):  
Biological Sciences ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
High Performance ◽  
Condensation Reaction ◽  
Aromatic Aldehydes ◽  
New Materials ◽  
One Pot ◽  
High Yields ◽  
Benzaldehyde Derivatives

Aim and Objective: The reaction of cyclohexylisocyanide and 2-aminopyridine-3- carboxylic acid in the presence of benzaldehyde derivatives in ethanol led to 3-(cyclohexylamino)-2- arylimidazo[1,2-a]pyridine-8-carboxylic acids in high yields. In a three component condensation reaction, isocyanide reacts with 2-aminopyridine-3-carboxylic acid and aromatic aldehydes without any prior activation. Material and Methods: The synthesized products have stable structures which have been characterized by IR, 1H, 13C and Mass spectroscopy as well as CHN-O analysis. Results: In continuation of our attempts to develop simple one-pot routes for the synthesis of 3- (cyclohexylamino)-2-arylimidazo[1,2-a]pyridine-8-carboxylic acids, aromatic aldehydes with divers substituted show a high performance. Conclusion: In conclusion, this study introduces the art of combinatorial chemistry using a simple one-pot procedure for the synthesis of new materials which are interesting compounds in medicinal and biological sciences.

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