Simultaneous determination of atorvastatin and its metabolites in human plasma by UPLC-MS/MS

2017 ◽  
Vol 9 (6) ◽  
pp. 1038-1045 ◽  
Author(s):  
Liyun Cai ◽  
Zhijie Zheng ◽  
Xipei Wang ◽  
Lan Tang ◽  
Liping Mai ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Simultaneous Determination ◽  
Human Plasma ◽  
Ultra Performance Liquid Chromatography ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry

A rapid, sensitive and selective ultra-performance liquid chromatography mass spectrometry (UPLC-MS/MS) method was developed and validated for the quantification of atorvastatin and all its as-yet-identified metabolites in human plasma.

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