Introduction to the themed issue ‘The health benefits of UV radiation exposure through vitamin D production or non-vitamin D pathways’

2017 ◽  
Vol 16 (3) ◽  
pp. 281-282 ◽  
Author(s):  
Prue H. Hart ◽  
Mary Norval ◽  
Vivienne E. Reeve

Sun exposure stimulates vitamin D production in addition to several immunomodulatory pathways. Fifteen perspectives in this themed issue aim to distinguish the contribution of vitamin D-dependent and independent pathways, initiated by UV radiation exposure, to beneficial health outcomes.

2017 ◽  
Vol 16 (3) ◽  
pp. 374-380 ◽  
Author(s):  
Richard B. Weller

UV photoreduces nitrogen oxides sequestered in the skin. The resulting NO moves to the systemic circulation where it vasodilates and lowers BP.


2008 ◽  
Vol 105 (2) ◽  
pp. 668-673 ◽  
Author(s):  
J. Moan ◽  
A. C. Porojnicu ◽  
A. Dahlback ◽  
R. B. Setlow

2021 ◽  
pp. 30-35
Author(s):  
Suzanne J. Dobbinson ◽  
Afaf Girgis ◽  
Bruce K. Armstrong ◽  
Anne E. Cust

This chapter covers epidemiologic evidence for the association of ultraviolet (UV) radiation with cancer, psychosocial and behavioral research on sun exposure and sun protection, and mixed messages regarding the role of vitamin D in influencing cancer risk. The focus is primarily on sun exposure, but indoor tanning is also covered. The evidence is convincing for a causal relationship between UV radiation and skin cancer, but there appears to be a protective association of UV radiation with some internal cancers, namely colorectal, prostate, and breast cancers and non-Hodgkin lymphoma. This association may or may not be mediated by cutaneous vitamin D production. Predictors of sun exposure and sun protection behaviors and recommendations for UV protection are reviewed. A summary of psychosocial and behavioral skin cancer prevention interventions and approaches for different target groups is presented and linked to theoretical models that help to explain behavior change.


2015 ◽  
Vol 85 (1-2) ◽  
pp. 23-30 ◽  
Author(s):  
Aneta Aleksova ◽  
Rita Belfiore ◽  
Cosimo Carriere ◽  
Salam Kassem ◽  
Salvatore La Carrubba ◽  
...  

Abstract. Background: Hypovitaminosis D is a vitamin deficiency that has been increasing in developed countries; it was also suggested as an emerging risk factor for developing of atherosclerosis and acute myocardial infarction. The primary source of vitamin D is its cutaneous synthesis under exposure to sunlight. It has been suggested that 30 min of sun exposure twice weekly leads to sufficient vitamin D synthesis. The residents of Trieste (Italy) are well-known for their high exposure to sunlight in all seasons. We aimed to investigate the vitamin D status in subjects with acute myocardial infarction living in this area. Methods: Vitamin D status was identified in 478 subjects diagnosed with acute myocardial infarction. Results: The median serum 25-hydroxyvitamin D concentration was 14.5 [7.8 - 22.7] ng/mL. Vitamin D deficiency and insufficiency were present in 324 (68 %) and 107 (22 %) subjects, respectively. Vitamin D deficiency was less frequent among subjects enrolled in the period from July to the end of September (p < 0.001). In a multivariate analysis vitamin D deficiency was predicted by older age (p = 0.02), female gender (p = 0.002), higher body mass index (p = 0.05), autumn/winter sampling (p < 0.001), increased parathyroid hormone (p = 0.03) and alkaline phosphatase (p = 0.003). Conclusions: We observed very high prevalence of vitamin D deficiency among subjects with myocardial infarction in all seasons of enrollment. However, it was lower in the summer when sun exposure is higher. The exposure to sunlight may be a cost-saving therapeutic strategy for the management of vitamin D deficiency.


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