Radiation-Induced Meningioma of the Orbit: Natural History, Potential for Malignant Transformation, and Surgical Management

2013 ◽  
Vol 74 (S 01) ◽  
Author(s):  
Dustin Hayward ◽  
Tarik Ibrahim ◽  
David Yoo ◽  
Darl Vandevender ◽  
Vikram Prabhu
Keyword(s):  
Natural History ◽  
Malignant Transformation ◽  
Surgical Management ◽  
Radiation Induced

Occurrence of seromucinous borderline tumours in the peritoneal lesions after bilateral salpingo-oophorectomy

2020 ◽  
Vol 13 (12) ◽  
pp. e234692
Author(s):  
Taihei Yamada ◽  
Satoko Eguchi ◽  
Ikuko Yokoo ◽  
Takahide Arimoto
Keyword(s):  
Malignant Transformation ◽  
Surgical Management ◽  
Previous History ◽  
Cancer Antigen ◽  
History Of

A 65-year-old woman with a previous history of bilateral salpingo-oophorectomy had peritoneal cysts, increasing in size over 15 years and an increasing cancer antigen 19–9 (CA 19–9) level. The size of the cysts eventually reached 86 mm and 70 mm. As malignant transformation of endometriosis was suspected, we performed peritoneal cystectomy and hysterectomy. Histopathology revealed seromucinous borderline tumours (SMBTs) derived from endometriosis. One month after surgery, her CA 19-9 level had decreased. It is rare for SMBT to occur after bilateral salpingo-oophorectomy; surgical management is the best treatment at present.

scholarly journals Natural history and treatment options of radiation-induced brain cavernomas: a systematic review

2021 ◽  
Author(s):  
Gildas Patet ◽  
Andrea Bartoli ◽  
Torstein R. Meling
Keyword(s):  
Systematic Review ◽  
Natural History ◽  
Radiation Treatment ◽  
Neurological Deficits ◽  
Cochrane Library ◽  
Average Dose ◽  
Cavernous Malformations ◽  
Radiation Induced ◽  
The Mean

AbstractRadiation-induced cavernous malformations (RICMs) are delayed complications of brain irradiation during childhood. Its natural history is largely unknown and its incidence may be underestimated as RCIMS tend to develop several years following radiation. No clear consensus exists regarding the long-term follow-up or treatment. A systematic review of Embase, Cochrane Library, PubMed, Google Scholar, and Web of Science databases, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, was performed. Based on our inclusion/exclusion criteria, 12 articles were included, totaling 113 children with RICMs, 86 were treated conservatively, and 27 with microsurgery. We were unable to precisely define the incidence and natural history from this data. The mean age at radiation treatment was 7.3 years, with a slight male predominance (54%) and an average dose of 50.0 Gy. The mean time to detection of RICM was 9.2 years after radiation. RICM often developed at distance from the primary lesion, more specifically frontal (35%) and temporal lobe (34%). On average, 2.6 RICMs were discovered per child. Sixty-seven percent were asymptomatic. Twenty-one percent presented signs of hemorrhage. Clinical outcome was favorable in all children except in 2. Follow-up data were lacking in most of the studies. RICM is most often asymptomatic but probably an underestimated complication of cerebral irradiation in the pediatric population. Based on the radiological development of RICMs, many authors suggest a follow-up of at least 15 years. Studies suggest observation for asymptomatic lesions, while surgery is reserved for symptomatic growth, hemorrhage, or focal neurological deficits.

scholarly journals Proton beam therapy for malignant transformation of intracranial epidermoid cyst

2019 ◽  
Vol 12 (7) ◽  
pp. e229388
Author(s):  
Zhe Chen ◽  
Masayuki Araya ◽  
Hiroshi Onishi
Keyword(s):  
Proton Beam ◽  
Malignant Transformation ◽  
Epidermoid Cyst ◽  
Clinical Case ◽  
Proton Beam Therapy ◽  
Facial Paresis ◽  
Surgical Interventions ◽  
Radiation Induced ◽  
Intracranial Epidermoid

We report the first clinical case on the successful use of proton beam therapy in the management of malignant transformation of intracranial epidermoid cyst. A 43-year-old man was initially diagnosed as this disease with left facial paresis, hypesthesia and hypoalgesia in the territories of the trigeminal nerve. After failure of surgical interventions, he was referred to our radiation centre. We performed a postoperative proton beam therapy for treatment. We delivered a total dose of 57 GyE in 31 fractions. He tolerated the treatment well with mild acute toxicities and remained healthy and functional by 2-year follow-up postradiotherapy. No evidence of delayed radiation-induced neurotoxicity was observed.

Surgical management of radiation-induced temporal lobe necrosis in patients with nasopharyngeal carcinoma: Report of 14 cases

Head & Neck ◽  
2010 ◽  
Vol 33 (10) ◽  
pp. 1493-1500 ◽  
Author(s):  
Yong-gao Mou ◽  
Ke Sai ◽  
Zhen-ning Wang ◽  
Xiang-heng Zhang ◽  
Yan-chun Lu ◽  
...  
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Surgical Management ◽  
Temporal Lobe ◽  
Temporal Lobe Necrosis ◽  
Radiation Induced
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