scholarly journals Placental Teratoma, Omphalomesenteric Duct Remnant, or Intestinal Organoid (Enteroid) Differentiation: A Diagnostic Dilemma

2017 ◽  
Vol 06 (04) ◽  
pp. 252-257
Author(s):  
Tarek Jazaerly ◽  
Stefan Kostadinov ◽  
Salwa Khedr

AbstractWe report an unusual case of fully developed fetal intestinal segment(s) within a nodule on the chorionic plate of the placenta of a 27-year-old female patient at 37 weeks gestation with spontaneous vaginal delivery. Gross examination of the placenta revealed a chorionic plate nodule near the insertion of the umbilical cord, which, upon microscopic evaluation, raised the differential diagnostic possibilities of placental teratoma, vitelline/omphalomesenteric duct anomaly, and intestinal organoid differentiation. We discuss the distinguishing features, morphogenesis, and clinical significance of the aforementioned entities and review the pertinent medical literature.

Author(s):  
Sachin Goel ◽  
Neha Jain ◽  
Ekta Narang ◽  
Suparna Roy

<p class="abstract">Sternocleidomastoid tumor of infancy (STOI) is a common cause of neck mass in the neonatal period. However, STOIs presenting bilaterally is a rare finding in medical literature. We herein report an unusual case of a bilateral STOI in a five-week infant. The child was given physical therapy which consisted of active and passive physical exercises, warm compresses and massage. Within 10 weeks the swellings reduced considerably in size. Bilateral, firm masses are often confused with lymphadenopathy and are inadvertently treated with antibiotics. Hence, STOI should be kept as an important differential diagnosis for neck mass in the neonatal period.</p>


2015 ◽  
Vol 33 (1) ◽  
pp. 179
Author(s):  
S Mohapatra ◽  
AM Kumar ◽  
M Deb ◽  
B Sharma

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Alison Finall

Surgical histopathologists are currently working in a context of high demand and requirement for fast turnaround times to report small diagnostic biopsies. Use of automated rapid cycle processing could improve turnaround times for reporting small biopsies. There are few papers in the medical literature describing detailed assessment of staining quality in verification of automated rapid cycle processing methods. This study assessed quality of immunohistochemical and haematoxylin and eosin staining of 62 paired endometrial biopsy samples processed using standard overnight cycles compared with rapid cycles of either 2, 3 or 4 hours duration. We found that small biopsies adequately fixed in 10% neutral buffered formalin were of sufficient staining quality for use in diagnostic reporting if they were processed for 3 or 4 hours. Five samples in our 2-hour group were of insufficient staining quality for full microscopic evaluation and histopathological diagnosis. As such, the 2-hour method was rejected. Rapid cycles of three hours duration will be adopted in our laboratory for processing small samples. Prospective monitoring of report turnaround times will be needed to assess impact on future outcomes for patients.


2018 ◽  
Vol 8 (5) ◽  
Author(s):  
Srikant S Chakravarthi ◽  
Srivathsa Veeraraghavan ◽  
Melanie Fukui ◽  
Jonathan Jennings ◽  
Richard A Rovin ◽  
...  

2020 ◽  
Vol 4 (5) ◽  
pp. 446-448
Author(s):  
Ghassan Niaz ◽  
Ellen H De Moll ◽  
Lauren Zinns ◽  
Bryan Tassavor ◽  
Robert G Phelps

Mucoceles are one of the most common benign mucosal growth in the oral cavity. They may be under-recognized in children. Mucoceles infrequently present in groups. We present an unusual case of eruptive superficial mucoceles in a 6-day old male that served as a diagnostic dilemma.


2006 ◽  
Vol 120 (7) ◽  
pp. 594-596
Author(s):  
N P Shine ◽  
K Lew

Keloid scarring is a benign hyperproliferation of fibrous tissue occurring at a wound healing site. Keloid formation related to the ear is generally the result of ear-piercing, mainly causing cosmetic disfigurement. We present an unusual case of keloid formation at a previous meatoplasty incision scar in a 10-year-old Caucasian with a modified radical mastoid cavity. This lesion prevented the cavity from self-cleaning and obstructed microscopic evaluation of the cavity. Treatment was successfully performed by surgical excision, with closure of the defect using supra-keloid skin flaps, followed by serial steroid injection therapy.


2005 ◽  
Vol 8 (5) ◽  
pp. 533-540 ◽  
Author(s):  
Kadria Sayed ◽  
Van H. Savell ◽  
Robert E. Hutchison ◽  
James Kepner ◽  
Michael P Link ◽  
...  

Financial considerations have led to suggestions that routine microscopic evaluation of tonsils and adenoids is neither cost effective nor clinically indicated. However, the possibility of tonsillar lymphoma must be carefully weighed when making institutional policy decisions. One way to find an appropriate algorithm for pathologic examination is to examine the characteristics of biopsy-proved tonsillar lymphomas. To investigate the clinicopathologic characteristics of tonsillar lymphoma, we performed a retrospective analysis of patients who had non-Hodgkin lymphoma (NHL) and large-cell or Burkitt lymphoma involving the tonsils and adenoids and were registered on Pediatric Oncology Group (POG) protocols. Seventy-seven (9%) of 832 POG cases of NHL involved the tonsils and adenoids. Review of the pathology reports available from 29 of these cases revealed that NHL was incidentally discovered by pathologic examination in only 5 cases, all of which had clinical evidence of unilateral tonsillar enlargement or size discrepancy by gross examination. The other 24 cases indicated a clinical suspicion of tonsillar cancer, as judged by a preoperative diagnosis or by a request for frozen-section examination. We conclude that in most cases there is a clinical suspicion of tonsillar NHL at the time of gross examination. With routine cases, we predict that the use of comparative organ weights, a clinical impression of tonsillar asymmetry, and review of clinical history will increase the recognition of tonsillar lymphoma when “gross-only” protocols are employed for specimen handling.


2013 ◽  
Vol 127 (S2) ◽  
pp. S48-S50 ◽  
Author(s):  
C Y Tan ◽  
S Chong ◽  
C-K L Shaw

AbstractObjective:To report an unusual case of a primary mastoid cyst (congenital or developmental) in a patient without otological symptoms.Method:Case report and review of the English language literature.Results:Primary mastoid cyst is a newly reported and very rare pathological entity. Mastoid cysts usually occur secondary to chronic infection, inflammation or trauma. Review of the medical literature highlights the rarity of this condition.Conclusion:This report describes the experience gained by the diagnosis and management of this patient. It emphasises the importance of clinical vigilance so that proper treatment may be instituted in a timely manner.


2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Ahmad Al-Mousa ◽  
Mohammad Nour Shashaa ◽  
Mohamad Shadi Alkarrash ◽  
Mohamad Alkhamis ◽  
Lina Ghabreau ◽  
...  

Abstract Background Seminoma is the most common subtype of testicular cancer and occurs most commonly in patients aged 30–49 years, but decreases to a very low level in men in their 60s or older. Case presentation A 90-year-old Syrian man with a 6-year history of an increase in size of his right scrotum, presented to the urological clinic and, on clinical examination, the findings suggested testicular tumor. After orchiectomy and histology results based on microscopic and immunohistochemical examinations, a pure seminoma was diagnosed, so we describe in this case report the second-oldest patient with classical seminoma in the medical literature. Conclusion This case report has been written to focus on the probability of any type of testicular tumor occurring at any age or decade; urologists should consider seminoma as a differential diagnosis with any testicular swelling even in elderly patients.


HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S433
Author(s):  
Gunjan Desai ◽  
Prasad Pande ◽  
Rajiv Shah ◽  
Palepu Jagannath

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