A rare cause for discomfort of the legs

Phlebologie ◽  
2009 ◽  
Vol 38 (06) ◽  
pp. 267-269 ◽  
Author(s):  
T. Hofer

SummaryThis paper presents two women who visited the phlebology surgery in the opinion that varices would be responsible for their symptoms. Patient 1 complained of nocturnal pain that radiated from the posterior surface of the left thigh to the anterior and lateral surfaces of the knee and lateral aspect of the calf. This pain occurred whenever she changed position. Patient 2 felt numbness in her right foot and an annoying burning sensation in her right heel. She was known to have lumbar discopathy and stenosis of the spinal canal which however, according to neurological diagnosis, could not explain the symptoms. On clinical examination neither had visible nor palpable varices, nor any recognisable dermal signs of venous hypertension. However, it was conspicuous that the left foot of patient 1 barely reached the floor when she was sitting down. In patient 2 the circumference of the right calf was increased by 2 cm.In both cases a coarse, circumscribed thickening was palpable deep in the posterior surface of the thigh (patient 1) and the proximal calf (patient 2). This was responsible for the asymmetrical posture in sitting of patient 1. Doppler/duplex sonography did not reveal any pathological findings in either patient. Thanks to MRI scans the cause in both cases was found to be a subfascial tumour that was displacing the musculature, thus compressing nervous structures; once in the thigh (patient 1: 600 g), once in the calf (patient 2: 200 g). In both women the symptoms disappeared after surgical extirpation of the clinically and histologically verified lipomas.

Author(s):  
Shaughnelene Smith

The goal of this project was to investigate the genetic heritability of hippocampal volume using twin pairs and assess the neuroanatomical structures of the hippocampus and how these properties relate to memory in humans. Data for this project was obtained from the Human Connectome Project: a data bank established to provide neural images to the public. MRI scans were used to obtain brain images of each of the participants and basic cognitive tasks were used to obtain memory ability. To date, 506 subjects have been analyzed: 66 monozygotic twin pairs, 44 dizygotic twin pairs, and 47 sibling pairs. The data collection for of this project was three-fold. First, segmentations were performed to calculate the volume of the anterior and posterior regions of the hippocampus. Secondly, the magnitudes of hippocampus dentations were recorded within the three segments – the head, body, and tail – of the hippocampus. Lastly, visual inspection was used to asses incomplete inversions, which was defined as an atypical anatomical pattern in the hippocampus. The results of this project showed a strong heritability observed on the right anterior hippocampus (hb2=1.365) and right amygdala (hb2=1.315), moderate heritability observed on the left posterior hippocampus (hb2=0.765), and weak heritability observed on the right posterior hippocampus (hb2=0.2654). This indicates that hippocampal volumetric heritability showed strong genetic control for the right hemisphere and strong environmental control for the left hemisphere. The project is still in the process of correlating the anatomical structures to the memory capabilities of the participants. 


1926 ◽  
Vol 22 (5-6) ◽  
pp. 511-513
Author(s):  
V. N. Ternovsky ◽  
M. Sadykova

Dissecting the muscles of the right lower limb of an unknown corpse, we found an accessory muscle on the posterior surface of the lower leg. This muscle (see Fig.) Was bordered behind in. soleus and with the tendon m. plantaris, in front - with in. flexor hallucis longus, medially - c m. flexor digitorum longus and laterally - c m. peroneus brevis.


2014 ◽  
Vol 7 (1) ◽  
pp. 56-58
Author(s):  
Savelina L. Popovska ◽  
Tatyana M. Betova ◽  
Кrasimir T. Petrov

Abstract Fibromatoses are a group of benign proliferations of fibrous tissue with clinical behaviour ranging from that of truly malignant tumours to that of benign reactive fibrous proliferations. Some of the superficial fibromatoses are fairly common but deep ones, also known as desmoid tumours or musculoaponeurotic fibromatoses, are rare. We describe a case of extra-abdominal musculo- aponeurotic fibromatosis in a 22-years old male. He underwent 14 operations for a period of 9 years for fibromatosis of the posterior surface of the right lower limb. The histological findings of the lesions were similar consistent across surgeries and consistent with a diagnosis of aggressive extra-abdominal fibromatosis.


2019 ◽  
Vol 47 ◽  
Author(s):  
Gabriela De Carvalho Cid ◽  
Luciano Da Silva Alonso ◽  
Ana Paula De Castro Pires ◽  
Mariana Siqueira d'Avila Taïna Gonçalves ◽  
Taïna Gonçalves ◽  
...  

Background: Congenital cardiac diseases are a common cause of death in puppies. Tricuspid valve dysplasia is characterized by thickening and displacement of the leaflets of the tricuspid valve, agenesis of the valves, and incomplete separation of valve components. Papillary muscles may fuse and display shortened or absent chordae tendineae that contribute to tricuspid regurgitation. Diagnostic features of tricuspid valve dysplasia include cardiomegaly with massive right atrium enlargement on thoracic radiography and tricuspid insufficiency on an ultrasound. We aimed to describe clinicopathological findings in a dog (Canis familiaris) with tricuspid dysplasia.Case: We aimed to describe tricuspid valve dysplasia in a dog referred for necropsy at the Anatomical Pathology Sector of The Rural Federal University of Rio de Janeiro, Brazil, with a clinical history of abdominal swelling, dyspnea, cyanosis, ascites, and prostration. Echocardiography and abdominal ultrasound revealed right ventricular enlargement, hepatomegaly, and splenomegaly. Examination of the heart showed prominent enlargement, thickening and dilation of the right chambers, thickening of the tricuspid leaflets, and moderately shortened chordae tendineae. The liver was enlarged, with a nutmeg pattern, and foci of clotting and fibrin adhesions in the lateral right lobule.Discussion: Epidemiological, clinical, and pathological findings were consistent with tricuspid valve dysplasia. Although structural abnormalities of the tricuspid and mitral valves are well known in fetuses and neonates, congenital and secondary tricuspid malformations are rare in dogs. The survival rate is associated with the severity of heart lesions. Tricuspid valve dysplasia is mostly observed in large-breed dogs (>20 kg), particularly in Labrador Retrievers, Boxers, and German Shepherds. Regardless, most dogs with tricuspid valve dysplasia are of a pure-breed, which differs from our findings because our dog was a mongrel. Our dog displayed signs of dyspnea, cyanosis, abdominal swelling, prostration, and enlarged liver and spleen on ultrasound examination. Tricuspid valve dysplasia led to heart enlargement and right congestive heart failure, with consequent ascites, abdominal swelling, weakness, lethargy, jugular venous distension, and hepatomegaly. Overall, the heart showed prominent enlargement, thickening and dilation of the right chambers, thickening of the tricuspid leaflets, and moderately shortened chordae tendineae. The liver had a nutmeg pattern. Tricuspid valve dysplasia is characterized by malformation of the tricuspid valve leaflets, chord tendineae, or papillary muscles. Malformed tricuspid valves are known to result in variable degrees of regurgitation, leading to right atrial overflow and ventricular eccentric hypertrophy. Differential diagnosis includes myocarditis, tricuspid valve endocarditis, tricuspid endocardiosis, tricuspid valve prolapse and right ventricular dysplasia, right ventricular enlargement with tricuspidal regurgitation due to pulmonary insufficiency, and arrhythmogenic right ventricular cardiomyopathy. Signs of heart murmurs (irregular sounds of the heart) on clinical examination may indicate an irregular blood flow pattern, and imaging tests may be necessary for assessing the presence and severity of any lesions. The epidemiologic, clinical, and pathological findings were consistent with those of tricuspid valve dysplasia. 


Author(s):  
Gilbert C. Bourne

The following description of the reproductive organs of the oyster cannot well be understood without some acquaintance with the general anatomy of the animal. With the help of Pl. XXII, fig. 1, the most important features of its anatomy may readily be understood. It must be remembered that the valves of the oyster's shell lie right and left of the animal; that the concave valve which lies undermost in the natural position of the animal is the left valve, and the flat upper valve is the right valve. The hinge marks the dorsal border of the animal, and the opposite border is the ventral border. That side which is on the observer's right in fig. 1 is the anterior surface, and that on the left hand is the posterior surface. As the animal is compressed from side to side the anterior and posterior surfaces are very narrow. The great adductor muscle, by which the valves of the shell are closed, is seen lying in the centre of the animal in fig. 1.


1987 ◽  
Vol 2 (3) ◽  
pp. 173-179 ◽  
Author(s):  
Syde A. Taheri ◽  
Paul Nowakowski ◽  
David Pendergast ◽  
Julie Cullen ◽  
Steve Pisano ◽  
...  

The iliocaval compression syndrome is a disorder, frequently found in young women, in which extrinsic compression of the left iliocaval junction produces signs and symptoms of lower extremity venous insufficiency. The anatomic variant which gives rise to this syndrome consists of compression of the left common iliac vein by the overlying right common iliac artery, near its junction with the vena cava. Additional reduction of outflow results from intraluminal venous webs and tight adhesions between the iliac artery and vein. Pain, swelling, pigmentation, and venous claudication characterize this syndrome, which affects predominantly the left leg. The syndrome may progress to iliofemoral thrombosis, phlegmasia cerulea dolens, and venous gangrene. Longstanding iliocaval stenosis may produce valvular incompetence. Exercise plethysmography is a non-invasive test useful in screening patients for iliocaval compression. The definitive diagnosis is made by venography, both ascending and descending, to determine the degree of outflow stenosis. Iliocaval patch angioplasty with retrocaval positioning of the right iliac artery, decreases venous hypertension and leads to improvement in the clinical condition. To date, we have performed iliocaval angioplasty, with retrocaval repositioning of the right common iliac artery, on 18 patients. Of these, 83% have had good results as determined by hemodynamic and clinical assessment.


The author, while dissecting a gravid uterus of seven months, on the 8th of April, 1838, observed the trunk of a large nerve proceeding upwards from the cervix to the body of that organ along with the right uterine vein, and sending off branches to the posterior surface of the uterus; some of which accompanied the vein, and others appeared to be inserted into the peritoneum. A broad band, resembling a plexus of nerves, was seen extending across the posterior surface of the uterus, and covering the nerve about midway from the fundus to the cervix. On the left side, a large plexus of nerves was seen, surrounding the uterine veins at the place where they were about to enter the hypogastric vein. From this plexus three large trunks of nerves were seen accompanying the uterine vein, which increased in size as they ascended to the fundus uteri. From the nerve situated on the posterior surface of the vein, numerous filaments passed off towards the mesial line, as on the right side; some following the smaller veins on the posterior surface of the uterus, and others becoming intimately adherent to the peritoneum. The largest of the nerves which accompanied the uterine vein was traced as high as the part where the Fallopian tube enters the uterus; and there it divided into numerous filaments, which plunged deep into the muscular coat of the uterus along with the vein. A large fasciculated band, like a plexus of nerves, was also seen on the left side under the peritoneum, crossing the body of the uterus; and several branches, apparently nervous, proceeding from this band, were distinctly continuous with some of the smaller branches of nerves accompanying the uterine veins. The preparation of the parts was placed in the Museum of St. George’s Hospital, on the 1st of October, 1838; and several anatomists who examined it were of opinion that they were absorbents accompanying the uterine veins, and tendinous fibres spread across the posterior surface. Dr. Lee availed himself of another opportunity which presented itself, on the 18th of December of the same year, of examining a gravid uterus in the sixth month of pregnancy, which had the spermatic, hypogastric and sacral nerves remaining connected with it; and during the last ten months, he has been diligently occupied in tracing the nerves of this uterus. He believes that he has ascertained that the principal trunks of the hypogastric nerves accompany, not the arteries of the uterus, as all anatomists have represented, but the veins; that these nerves become greatly enlarged during pregnancy; and that their branches are actually incorporated, or coalesce with the branches of the four great fasciculated bands on the anterior and posterior surface of the uterus, bearing a striking resemblance to ganglionic plexuses of nerves, and sending numerous branches to the muscular coat of the uterus.


2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
T. B. Neuschwander ◽  
B. R. Macias ◽  
A. R. Hargens ◽  
Q. Zhang

We studied the effect of mild external leg compression on both skin and muscle microvascular flow, and muscle oxygenation in the leg of healthy subjects during simulated venous hypertension. Skin and muscle microvascular blood flows were measured using photoplethysmography (PPG), and muscle oxygenation was measured using near-infrared spectroscopy (NIRS). Both PPG and NIRS probes were placed over the anterior compartment of the right leg in 8 healthy subjects. Measurements were taken under three experimental conditions: external leg compression (40 mmHg); simulated venous hypertension (65 mmHg thigh cuff); external leg compression during simulated venous hypertension. Muscle oxygenation was measured only under external leg compression during simulated venous hypertension. Simulated venous hypertension decreased skin and muscle microvascular blood flows from 100% (baseline) to 35.8±2.9% and 31.9±1.3% (P<0.001), respectively. External leg compression during simulated venous hypertension caused 2-fold increases in both skin and muscle microvascular blood flows compared to simulated venous hypertension (P<0.001). Similarly, external leg compression during simulated venous hypertension significantly restored muscle oxygenation by 23±7% compared to its baseline (P<0.05). Our results demonstrate that mild external leg compression counteracts the decreases in skin microvascular flow, muscle microvascular flow, and muscle oxygenation induced by simulated venous hypertension in the leg.


2014 ◽  
Vol 26 (5) ◽  
pp. 1118-1130 ◽  
Author(s):  
Nandita Vijayakumar ◽  
Sarah Whittle ◽  
Murat Yücel ◽  
Meg Dennison ◽  
Julian Simmons ◽  
...  

Maturation of cognitive control abilities has been attributed to the protracted structural maturation of underlying neural correlates during adolescence. This study examined the relationship between development of two forms of cognitive control (proactive and reactive control) and structural maturation of the ACC, dorsolateral pFC, and ventrolateral pFC (vlPFC) between early and mid adolescence using a longitudinal design. Adolescents (n = 92) underwent baseline assessments when they were 12 years old and follow-up assessments approximately 4 years later. At each assessment, structural MRI scans were acquired, and a modified Stroop task was performed. Results showed longitudinal improvements in reactive control between early and mid adolescence. Furthermore, magnitude of the improvement in proactive control was associated with reduced thinning of the right vlPFC across the sample, whereas the magnitude of the improvements in reactive control was associated with reduced thinning of the left ACC in men alone. These findings suggest that individual differences in the maturation of ACC and vlPFC underlie the development of two distinct forms of cognitive control between early and mid adolescence as well as highlight sex differences in this relationship.


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